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"Smithies, Andrew"
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NICETAS PAPHLAGO'S \LIFE OF IGNATIUS\: A CRITICAL EDITION WITH TRANSLATION. (ANCIENT GREEK AND ENGLISH TEXT) (BYZANTINE, SCHISM)
Nicetas Paphlago's Life of Ignatius is closely linked with the so-called anti-Photian collection, a body of material compiled about 900 A.D. in support of the Ignatian side and in condemnation of the part played by Photius in the first major schism between the Greek and Roman Churches. Since is was written soon after the events described, the Life of Ignatius, despite its obvious bias, provides important source material for the history of the period. Eleven manuscripts containing the Greek text of the Life of Ignatius survive in various European libraries, and working from microfilm copies, I intend to examine and collate all these versions with a view to establishing the text that most closely approaches the lost original. Important variant readings will be recorded separately in a critical apparatus and allusions to Biblical passages will be identified and cross-referenced. I shall also translate the work into English and provide a name-index for persons mentioned in the text. In the introduction I intend to give background information on the author and his work and to discuss the most likely date of composition. I shall also describe how the individual manuscripts are related to one another on historical as well as linguistic grounds. Hence, wherever possible I shall provide information or speculation on the circumstances of their copying as well as giving the technical detail of which manuscript was copied from which. I shall also explain the editorial conventions I have followed in setting up the text.
Dissertation
Mobile device and app use in paediatric emergency care: a survey of departmental practice in the UK and Ireland
IntroductionMobile devices and medical apps are used by healthcare professionals in adult and paediatric emergency departments worldwide. Recently, there has been a drive toward increased digitalisation especially in the UK. This point prevalence survey aims to describe hardware and software provision and their use in paediatric emergency care in the UK and Ireland.MethodsA web-based self-report questionnaire of member sites of an international paediatric emergency research collaborative was performed. A lead site investigator completed the survey on behalf of each site.ResultsOf the 54 sites, 46 (85%) responded. At 10 (21.7%) sites, the use of a personal mobile device at the bedside was not allowed; however, this was only enforced at 4 (8.7%) of these sites. Apple iOS devices accounted for the majority (70%) of institutional mobile devices. Most sites provided between 1 and 5 medical apps on the institutional mobile device. The British National Formulary (BNF/BNFc) app was the app which was most frequently provided and recommended. No site reported any harm from medical app use.ConclusionThe breadth of app use was relatively low. There was variability in trust guidance on app use and challenges in accessibility of Wi-Fi and devices.
Journal Article
Correction of Factor IX Deficiency in Mice by Embryonic Stem Cells Differentiated in vitro
Murine embryonic stem (ES) cells are pluripotent, but significant functional engraftment does not occur when they are introduced into the liver. However, here we demonstrate that functional liver engraftment does occur if the ES cells (from strain 129 mice) are first differentiated in vitro for 7 days in the presence of FGF. Strikingly, when these differentiated cells, termed putative endodermal precursors (PEPs), were injected into their livers, two of six C57BL/6 and four of eight BALB/c factor IX (F-IX)-deficient mice survived for >7 days, even though the recipients were of a different strain and, in the case of the BALB/c recipients, had a complete MHC mismatch. F-IX was detected in all six of the PEP-injected survivors. Two mice subsequently died of causes unrelated to F-IX; the others survived until death at 38 or 115 days after the transplantation. No uninjected control F-IX-deficient mice survived for >7 days. Large confluent regions of sinusoidal PEP engraftment were demonstrated by immunofluorescence in the long-term BALB/c survivors. The PEP engraftment was not associated with detectable cell fusion, and the transplantation was accompanied with only a low incidence of teratoma formation.
Journal Article
Correction of factor IX deficiency in mice by embryonic stem cells differentiated in vitro
Murine embryonic stem (ES) cells are pluripotent, but significant functional engraftment does not occur when they are introduced into the liver. However, here we demonstrate that functional liver engraftment does occur if the ES cells (from strain 129 mice) are first differentiated in vitro for 7 days in the presence of FGF. Strikingly, when these differentiated cells, termed putative endodermal precursors (PEPs), were injected into their livers, two of six C57BL/6 and four of eight BALB/c factor IX (F-IX)-deficient mice survived for >7 days, even though the recipients were of a different strain and, in the case of the BALB/c recipients, had a complete MHC mismatch. F-IX was detected in all six of the PEP-injected survivors. Two mice subsequently died of causes unrelated to F-IX; the others survived until death at 38 or 115 days after the transplantation. No uninjected control F-IX-deficient mice survived for >7 days. Large confluent regions of sinusoidal PEP engraftment were demonstrated by immunofluorescence in the long-term BALB/c survivors. The PEP engraftment was not associated with detectable cell fusion, and the transplantation was accompanied with only a low incidence of teratoma formation.
Journal Article
Lowy spurns embattled Sepp
A total of 14 administrators and sports marketing chiefs have been indicted in what US officials are calling a \"World Cup of fraud\".
Newspaper Article
He's our only friend in the world --- Qatar 2022
With Qatar accused of buying the World Cup with its generous bid, Walker said Australia was just too honest and called for FIFA president Sepp Blatter to reform his organisation in the same way as IOC president Juan Antonio Samaranch reformed the corruption-ridden Olympic committee.
Newspaper Article