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Background Stunting is one of the most serious and challenging public health problems in Ethiopia, which constitute a significant obstacle to achieving better child health outcomes. This study aimed to assess the prevalence and factors associated with stunting among 6–12 years old children in Humbo district, Southern Ethiopia. Methods This was a cross-sectional study conducted among 633 children 6–12 years old living in Humbo district, Southern Ethiopia, from March to April, 2015. A multistage cluster sampling technique was used to select participants from households in eight Villages in the study area. Height was measured using standard methods and height for age Z-score was computed to assess stunting. EPI info version 3.5.4 was used for data entry, whereas Anthroplus software and SPSS version 20.0 were used for computation of height for age Z-scores and statistical analyses respectively. Simple and multiple logistic regression analyses were used to examine factors associated with stunting in the study sample, using 95% confidence limits (statistical significance set at p  < 0.050). Results Prevalence of stunting was 57%, about, 3.5% were severely stunted, 27.3% moderately stunted and 26.4% mildly stunted, and the mean (SD) was − 1.1 (±1.2). About 7 (1.1%) boys and 15 (2.4%) girls were severely stunted. Age groups 10–12 years had significantly higher rate of stunting than others. Age (AOR = 1.7, 95% CI = 1.1–2.6), big family size (AOR = 4.6, 95% CI = 2.2–9.5) and field disposal of wastes (AOR = 2.7, 95% CI = 1.2–5.8) were factors significantly associated with stunting. Conclusion This study exposed high rate of stunting among school age children. Stunting remains a noticeable attribute of rural school age children. Findings suggest the need to implement evidence-based school-aged rural children nutrition policy and strategies as well as need for intervention to improve domestic waste management system in the rural community.

Background Medicinal plants have wide medicament application used to prevent and management of many ailments. These plants are used for primary health care in pastoralist communities who are deprived of modern medical care. They possess extensive therapeutics bioactive coupled with varied chemical structures. However, scientific validation of efficacy and safety of plants used to treat the urinary tract infections haven’t been fully exploited. The aim of this study was to evaluate antimicrobial activity and screening phytochemicals of medicinal plants used to treat urinary tract infections. Methods In-vitro experimental study was carried out to evaluate the antimicrobial effect and screening phytochemical of Rumex abyssinicus, Cucumis pustulatus, Discopodium penninervium, Lippia adoensis, Euphorbia depauperata, and Cirsium englerianum. Against drug resistance microbes. 80% methanol was used for extraction of the plant parts. The susceptibility tests were investigated using disc diffusion and broth micro-dilution methods. Results The majority of tested extracts showed antimicrobial activity on two or more drug-resistant bacteria with MIC value (1.0–128.0 μg/ml) and 9–27 mm inhibition zone in diameter. Extracts obtained from C.englerianum and E. depauperate showed more potent antibacterial activity on MRSA and Enterococcus faecalis with IZ 25 and 27 mm respectively . E. coli and K. pneumoniae were inhibited by those extracts with IZ ranging 9–25 mm and 11–27 mm respectively. E.faecalis and K. pneumoniae were more susceptible bacteria to the respective extracts. R. abyssinicus showed promising antifungal effect with had 21 mm IZ and MIC range 16-32 μg/ml on C.albicans . Alkaloids, flavonoids, phenolic and terpenoid were common phytochemical characterized in majority of screened plants. Conclusion Tested extracts exhibited significant antibacterial and antifungal activity. Hence, further structural elucidation of bioactive that inhibited the growth of microbes aforementioned plants may be used as precursors for the synthesis of new antibiotics in the future.

Children's consumption of ultra‐processed foods (UPF) is increasing in Ethiopia, but relatively little is known about the specific feeding practices that underlie this pattern. The objective of this study was to explore patterns of consumption of UPF by infants and young children within a broader context of inappropriate complementary feeding practices in extremely poor households in rural Oromia, Eastern Ethiopia. A formative qualitative study was conducted using semistructured interview questionnaires developed drawing on a socioecological model. A total of 16 focus group discussions with mothers (45 respondents), fathers (21 respondents) and grandmothers (23 respondents) of children aged 6–23 months in households that were beneficiaries of the Productive Safety Net Program were conducted, along with four key informant interviews with health workers. Qualitative transcripts were complemented with field notes before qualitative content analysis was applied. The key findings suggest that UPF were widely provided to infants and young children as part of a pattern of suboptimal complementary feeding, including both early and late initiation of complementary foods. In particular, UPF (including juice, biscuits and lipid‐based nutrient supplements) were diluted with or dissolved in water and fed to infants via bottle, often before the recommended age of initiation of 6 months. Mothers and caregivers reported that they perceived the products to be affordably priced and packaged, ready to use and convenient given their time constraints. The level of consumption of UPF and its effects on infant and young child feeding feeding practices and children's nutritional status in rural Ethiopia should be further explored. This qualitative analysis explored patterns of complementary feeding and consumption of ultra‐processed foods by infants and young children in poor rural households that are beneficiaries of the Productive Safety Net Program in Ethiopia. The evidence shows that these foods are often introduced during the period of complementary feeding because mothers and caregivers believe them to be nutritious, convenient (when diluted and provided to infants via bottle) and affordably priced. Key messages A range of inappropriate complementary feeding practices for infants and young children were observed in this sample of extremely poor households in rural Oromia, including both early and late initiation of complementary foods and an overreliance on a liquid diet. The perception that young children should initiate complementary feeding with liquids resulted in the heavy use of ultra‐processed foods (UPF), such as biscuits and packed juice, soft drinks and lipid‐based nutrient supplements; these foods were reported to be dissolved in or diluted with water. Respondents reported that UPF were available for purchase in small and affordable quantities, and also convenient to provide given maternal time constraints. Provision of UPF may increase the risk of gastrointestinal illness due to exposure to unclean water, and may also increase the risk of a nutritionally inadequate diet.

This study aimed to determine the prevalence of malnutrition and its association with wound healing and length of hospitalization among patients undergoing abdominal surgery admitted to hospitals in the Wolaita zone in southern Ethiopia. Methods. An institution-based prospective observational study was conducted in three hospitals in the Wolaita zone from August to October 2016. All eligible individuals aged between 19 and 55 years were recruited in this study. Anthropometric and biochemical analyses, such as serum albumin (Alb) and total lymphocyte count (TLC), were taken for nutritional assessment during the preoperative period. Quantitative variables were compared using Student’s t test. Cox’s regression was employed to determine which variables were possible risk factors for poor wound healing. Results. A total of 105 patients aged 19 to 55 with a mean age (±SD) of 34 ± 9.6 years were included, and the prevalence of preoperative malnutrition was 27.6%, 87%, according to BMI and nutritional risk index, respectively. Poor wound healing was significantly associated with underweight patients (BMI < 18.5 kg/m2) (AHR: 6.5 : 95%CI: 3.312.9), postoperative weight loss (AHR: 4.9; 95%CI: 2.8–8.5), and nutritional risk index (NRI) less than 97.5 (AHR 1.8; 95% CI: 1.09–3.1). Conclusion. The prevalence of malnutrition is high in our study setup; this is associated with an increased risk of adverse postoperative outcomes. Therefore, our results emphasize the need of routine preoperative nutritional assessment, optimizing nutritional status of patients and postoperative nutritional support.

Background In Ethiopia, 12.5% of children below 5 years are wasted, and 9.7% are moderately wasted. The present strategy for the management of moderate acute malnutrition (MAM) is a supplementary feeding program; however, this is only provided to chronically food-insecure areas. This randomized controlled non-inferiority trial examines if Local ingredients-based supplement (LIBS) is as effective as corn-soya blends plus (CSB+) in treating moderate acute malnutrition among children aged 6–59 months. Methods A randomized controlled non-inferiority trial will be conducted with moderately wasted children aged 6 to 59 months in Wolaita, Ethiopia. The calculated sample size is 324 (i.e. with 162 children in each of two arms, to be assigned by randomization). The daily ration will be: 100 g of LIBS plus 25.2 g of sugar with 8 ml oil in the intervention group, and 150 g of CSB+ with 16 ml of oil in the control group. These interventions will be provided for a maximum period of 12 weeks, with follow-up performed on a weekly basis. Data analysis will be done using SPSS and STATA software. Both intention-to-treat and per protocol analyses will be done. Hazard ratio and Kaplan-Meier (log rank) curves of survival analysis will be done to predict the probability of recovery rate. Logistic regression will be used to test for interactions between independent and dependent variables. Analysis of variances, t-tests, fisher’s exact test and chi-square tests will be used to assess baseline characteristics. Conclusions This paper will introduce to the existing research locally available nutritious foods which have the potential to enhance recovery from moderate acute malnutrition and to reduce the burden of malnutrition. The perceptions of mothers on feeding children with local ingredient-based supplementary food to assist recovery from moderate acute malnutrition will be the focus of in a qualitative study to follow; this will provide a further contribution in an evolving area of research. Trial registration Pan-African Clinical Trial Registration number: PACTR201809662822990 , retrospectively registered on 11/09/2018.

Background: The Coronavirus pandemic triggered a worldwide partial lockdown. The lockdown instigated the school’s shutdown making the students follow their courses in the virtual modalities while staying at home.Methods: The data were collected using an online survey using a semi-structured questionnaire. The study involved anonymous as well as voluntary 77 secondary schools (Grades 9th to 12th) and 132 university students (class standing 1st to 5th year).Results: The lockdown introduced excruciating experiences for most of the students; however, it also created unanticipated opportunities to learn new skills and develop insights on how to mitigate unforeseen crises while remaining reasonably productive. The steps taken to reduce exposure to the coronavirus infection showed a gender discrepancy. Accordingly, males were disproportionately taken risks regardless of the curfew imposed, while females were deeply concerned about the lockdown-induced break of social connections. Students who were attending public schools, presumably from low-income families were found to be more productive during the lockdown compared to their private school counterparts. This shows that, in some instances, the Coronavirus pandemic is a blessing in disguise. The lockdown created mixed feelings; accordingly, the students reported significantly varied responses towards it. This also introduced some inconsistencies in the response of the students. Perceptions about the lockdown and its impact in most instances significantly varied among students, which unlocked the opportunities to learn new lessons on how to manage unprecedented crises.Conclusion: Policymakers need to take into account gender and living standard while developing strategies to mitigate unprecedented challenges.

Overweight and obesity has become a major global health challenge that affects virtually all ages. The aim of this study is to assess the prevalence of overweight/obesity and associated factors among adults of Sodo Town, Southern Ethiopia. Community based cross sectional study was conducted from January to February 2016. A total of 370 households were selected from 14,551 household using a simple random sampling technique., Lottery method was used to select an adult individual with age of ≥25 years. Anthropometric measurements (height and weight) was assessed using the World Health Organization) recommended techniques. Data were analyzed using SPSS windows version 20 Software. Both bivariate and multivariable logistic regression analyses were done. Prevalence of overweight was 32.4% and obesity 16.2%. The combined prevalence of overweight/obesity was 48.6%. Factors associated with overweight/obesity were being female (AOR = 4.0; 95% of CI: 1.7−9.4), Age group between 35–44, 45–54 and age >55 were more likely to be overweight/obesity than age group 25–34 (AOR = 28; 95% CI:1.51–5.15), AOR = 2.44; 95%CI:1.12–5.32), AOR = 5; 95%CI:1.94–12-92) respectively. Similarly, having chronic illness (AOR = 2.9;95%CI:1.1–7.2), using Bajaj/car for transportation (AOR = 1.9; 95% of CI:1.1–3.3), spent 3–5 hours in sitting or reclining (AOR = 3.7;95% CI:1.6–8.5), taking one bottle of soft drink per day (AOR = 2.0;95% CI: 1.1–3.7) and those who consumed vegetable ≥3 times per day (AOR = 5.7; 95% of CI1.6–19.7). Prevalence of overweight/obesity among adult population in Sodo Town is high. Therefore, prioritizing counseling dietary modification about the risk of overweight /obesity in community level, provision of early care and treatment of chronic illness, regular physical exercise by avoiding sedentary life style are recommended.

Vitamin A deficiency is a public health problem in Ethiopia. However, there is paucity of evidence in Vitamin A deficiency among pregnant women in Ethiopia. Thus, this study aimed to determine the level of vitamin A deficiency and identify associated factors among pregnant women. A community-based cross-sectional study was conducted in Wolaita Sodo, Southern Ethiopia from May-July 2020. Four hundred twenty two pregnant women were selected by using simple random sampling. Serum retinol concentration was determined by using High-Performance Liquid Chromatography. Data were analyzed in RStudio and binary logistic regression analysis was done. Adjusted Odds Ratio (AOR) with 95% confidence intervals (CI) was reported. The prevalence of vitamin A deficiency among pregnant women was 21.8% and the mean serum retinol level was 0.92 µmol/L. Women Aged 30 years or older (AOR = 7.80, 95% CI: 1.69, 36.01), did not attend ANC follow-up (AOR = 5.38, 95% CI: 1.55, 18.71), and did not consume green leafy vegetables (AOR = 2.70, 95% CI: 1.16, 6.29) were more likely to become vitamin A deficient. On the other hand, women from a household with middle (AOR = 0.03, 95% CI: 0.005, 0.31), richer (AOR = 0.10, 95% CI: 0.03, 0.31), and richest (AOR = 0.02, 95% CI: 0.003, 0.18) wealth index, and have a dietary diversity score of four or more (AOR, 95% CI: 0.02, 0.12) had a lower odds of being vitamin A deficient. The prevalence of vitamin A deficiency among pregnant women in the study area was high. Food-based approaches that focus on dietary diversification like gardening of vegetables and poultry production should be promoted. Health extension workers should recommend pregnant women to attend ANC. We recommend further studies to perform serum alpha-1-acid glycoprotein and C - reactive protein analyses to adjust for inflammation.

Weight-for-height Z-score (WHZ) and mid-upper arm circumference (MUAC) are two independent anthropometric indicators for diagnosing and admitting children with severe acute malnutrition (SAM) for treatment. While severely wasted children are at high risk of mortality, MUAC and WHZ do not always identify the same population of children as having SAM. Understanding how this discrepancy relates to age and sex may provide valuable information for care programmes for children with SAM. Age and sex distribution for differences between children identified as SAM by MUAC and WHZ were examined and the degree of agreement calculated. Children (n = 4297) aged 6–59 months with validated anthropometric measures were recruited from a population-based survey conducted in rural southern Ethiopia. MUAC < 115 mm and WHZ < −3 were used to define severe wasting as per the World Health Organization (WHO) classification. The kappa coefficient (κ) was calculated. There was fair agreement between the MUAC and WHZ definitions of severe wasting in boys (κ = 0.37) and children younger than 24 months (κ = 0.32) but poor agreement in girls (κ = 0.15) and children aged 24 months and above (κ = 0.13). More research is needed on response to treatment and prediction of mortality using different anthropometric measurements in relation to ages and sex of children.

Currently, treatment of uncomplicated severe acute malnutrition is managed in the integrated Community based Outpatient Therapeutic Program (C-OTP) using ready-to-use therapeutic foods (RUTFs). The aim of this study was to determine challenges in implementing the critical steps in C-OTP and caregivers’ perceptions of service provision in southern Ethiopia. A total of 1048 caregivers of children admitted to the OTP and 175 Health Extension Workers (HEWs) from 94 selected health posts were included in the study. Program admission, follow-up and exit information was collected from caregivers during home visits. HEWs were interviewed at their respective health posts. Only 46.6% (481/1032) were given the recommended amount of RUTF and 19.3% (196/1015) were given antibiotics on admission. During C-OTP participation 34.9% (316/905) had uninterrupted provision of the recommended amount of RUTF. Of the children who left the program, 220/554 (39.7%) exited the program in line with the national recommendation. Caregivers (42.9% (394/918) and HEWs (37.1%, 62/167) perceive that RUTFs were being sold as a commodity. Inadequate provision and unintended usage of RUTFs, lack of antibiotics and inappropriate exit from the program were major constraints. For successful saving of lives, adequate resources must be allocated, and providers must be trained regularly, and supervised properly.