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This book is intended to help analytical chemists feel comfortable with more commonly used statistical operations and help them make effective use of the results. Emphasis is put upon computer-based methods that are applied in relation to measurement and the quality of the resulting data. The book is intended for analytical chemists working in industry but is also appropriate for students taking first degrees or an MSc in analytical chemistry.

The choice of treatment for PSA-detected, localized prostate cancer is influenced by effects of the interventions on quality of life. In the ProtecT trial, patterns of side-effect severity, improvement, and decline in urinary, sexual, and bowel function differed among the treatments. As reported in a companion article in the Journal, the U.K. National Institute for Health Research–supported Prostate Testing for Cancer and Treatment (ProtecT) trial has shown no significant difference in prostate-cancer–specific mortality or all-cause mortality among men with prostate cancer detected by prostate-specific antigen (PSA) testing who were randomly assigned to radical prostatectomy, active monitoring (a surveillance strategy), or radical conformal radiotherapy with neoadjuvant hormonal therapy, at a median of 10 years of follow-up; however, the ProtecT trial has shown higher rates of metastases and disease progression among men in the active-monitoring group than among men in the radical-treatment groups. . . .

Background Over the past decade genome-wide association studies (GWAS) have been applied to aid in the understanding of the biology of traits. The success of this approach is governed by the underlying effect sizes carried by the true risk variants and the corresponding statistical power to observe such effects given the study design and sample size under investigation. Previous ASD GWAS have identified genome-wide significant (GWS) risk loci; however, these studies were of only of low statistical power to identify GWS loci at the lower effect sizes (odds ratio (OR) <1.15). Methods We conducted a large-scale coordinated international collaboration to combine independent genotyping data to improve the statistical power and aid in robust discovery of GWS loci. This study uses genome-wide genotyping data from a discovery sample (7387 ASD cases and 8567 controls) followed by meta-analysis of summary statistics from two replication sets (7783 ASD cases and 11359 controls; and 1369 ASD cases and 137308 controls). Results We observe a GWS locus at 10q24.32 that overlaps several genes including PITX3 , which encodes a transcription factor identified as playing a role in neuronal differentiation and CUEDC2 previously reported to be associated with social skills in an independent population cohort. We also observe overlap with regions previously implicated in schizophrenia which was further supported by a strong genetic correlation between these disorders (Rg = 0.23; P  = 9 × 10 −6 ). We further combined these Psychiatric Genomics Consortium (PGC) ASD GWAS data with the recent PGC schizophrenia GWAS to identify additional regions which may be important in a common neurodevelopmental phenotype and identified 12 novel GWS loci. These include loci previously implicated in ASD such as FOXP1 at 3p13, ATP2B2 at 3p25.3, and a ‘neurodevelopmental hub’ on chromosome 8p11.23. Conclusions This study is an important step in the ongoing endeavour to identify the loci which underpin the common variant signal in ASD. In addition to novel GWS loci, we have identified a significant genetic correlation with schizophrenia and association of ASD with several neurodevelopmental-related genes such as EXT1 , ASTN2 , MACROD2 , and HDAC4.

By early October, 2009, there had been more than 340 000 reported cases of H1N1 infection in 191 countries, with more than 4100 deaths.1 WHO initially projected that up to 2 billion people could become infected with the virus over the next 2 years.2 Although vaccination programmes and other factors should reduce this number, plausible estimates of the number of infected individuals who might benefit from admission to intensive care range from 200 000 to 10 million. Beyond antiviral agents, anecdotal reports and data from animal studies suggest that illness severity can be attenuated by readily available agents, such as corticosteroids and statins, that can modulate the host's inflammatory response.9 None of these drugs has been adequately studied for efficacy.

Book Reviews in This Article: H. P. R. F inberg and V. H. T. S kipp . Local History: Objective and Pursuit. J. S. C ockburn , H. P. F. K ing , and K. G. T. M c D onnell (Eds). A History of the County of Middlesex, vol. i. Victoria History of the Counties of England. A. T. G aydon (Ed.). A History of the County of Shropshire, vol. VIII. Victoria History of the Counties of England. G. R. E lvey (Ed.). Luffield Priory Charters. Part 1. J. Z. T itow . English Rural Society, 1200‐1350. J oyce Y ouings . Tuckers Hall, Exeter: the History of a Provincial City Company through Five Centuries. J ames E. O xley . The Fletchers and Longbowstringmakers of London. G. G. C ruickshank. Army Royal: an Account of Henry VIII's Invasion of France, 1513. R. B. O uthwaite . Inflation in Tudor and Early Stuart England. E dwin W elch (Ed.). The Admiralty Court Book of Southampton, 1566‐1585. S helagh B ond (Ed.). The First Hall Book of the Borough of Mew Windsor, 1653‐1J25. H. E. S. F isher (Ed.). The South‐West and the Sea. Exeter Papers in Economic History, no. 1. L. M. C ullen . Anglo‐Irish Trade 1660‐1800. P eter M athias . The First Industrial Nation: An Economic History of Britain,1700‐1914 D. F. M c K enzie and J. G. R oss (Eds.). A Ledger of Charles Ackers, Printer of the London Magazine. F rances N orton M ason (Ed.). John Morton & Sons, Merchants of London and Virginia. D. E. V arley . John Heathcoat, 1783‐1861, Founder of the Machine‐Made Lace Industry. W. O. H enderson . Industrial Britain under the Regency 1814‐18: The Diaries of Escher, Bodmer, May andde Gallois. D uncan B ythell . The Handloom Weavers. A Study in the English Cotton Industry during the Industrial Revolution. C harles W ing . The Evils of the Factory System. J ohn R. K ellett . The Impact of Railways on Victorian Cities. D. I. G ordon . A Regional History of the Railways of Great Britain. Vol. v: The Eastern Counties. M. G. R eed (Ed.). Railways in the Victorian Economy. Studies in Finance and Economic Growth. C harles E. R aven . Christian Socialism, 1848‐1854. I an M ac D ougall (Ed.). The Minutes of Edinburgh Trades Council, 1859‐1873. A Century of Agricultural Statistics: Great Britain, i866‐ig66. L. N apolitan . The Centenary of the Agricultural Census. R onald G eorge G arnett . A Century of Co‐operative Insurance: The Co‐operative Insurance Society, i86y‐ig6y: A Business History. H enry P elling . Popular Politics and Society in Late Victorian Britain. S. B. S aul . The Myth of the Great Depression, 1873‐18g6. Studies in Economic History. D erek H. A ldcroft . British Railways in Transition: The Economic Problems of Britain's Railways since 1914. J ohn H ibbs . The History of British Bus Services. J. G ilchrist . The Church and Economic Activity in the Middle Ages. C. G. F. S imkin . The Traditional Trade of Asia. R alph L ee W oodward , J r . Class Privilege and Economic Development. The Consulado de Comercio of Guatemala, 1793‐1871. R. A. H umphreys . Tradition and Revolt in Latin America, and other essays. W. O. H enderson . The Industrialisation of Europe, ij8o‐igi4. E. R.J. O wen . Cotton andthe Egyptian Economy’, 1820‐1914. A Study in Trade and Development. R obert G reenhalgh A lbion . Naval and Maritime History: An Annotated Bibliography. 3rd edn, 2nd suppl. 1966‐8. E. H. P helps B rown with M argaret H. B rowne . A Century of Pay. The Course of Pay and Production in France, Germany, Sweden, the United Kingdom and the United States of America, i86a‐196o. H einrich B echtel . Wirtschqfts‐ und Sozialgeschichte Deutschlands: Wirtschaftsstile und Lebensformen von der VorzeitbiszurGegenwart. U lf D irlmeier . Mittelalterliche Hoheitsträgerim wirtschaftlichen Wettbewerb. W ilhelm A bel . Geschichte der deutschen Landwirtschaft vomfruhen Mittelalter bis zum 19. Jahrhundert. 2nd edn. F riedrich L ütge . Geschichte der deutschen Agrarver fassung vom frühen Mittelalter bis zum 19. Jahrhundert. 2nd edn. E va ‐M aria E ngel and B enedykt Z ientara . Feudalstruktur, Lehnbürgertum und Fernhandel im spätmittelalterlichen Brandenburg. Mit einer Einleitung von Eckhard Müller‐Mertens. H artmut S chiele and M anfred R icker . Betriebswirtschaftliche Aufschliisse aus der Fuggerzeit. E dith S chmitz . Leinengewerbe und Leinenhandel in Nordwestdeutschland, 1650‐1850. J ürgen K uczynski . Das Entstehen der Arbeiterklasse. H ermann K ellenbenz . Die Zuckerwirtschqft im Kölner Raum von der napoleonischen Zeit bis zur Reichsgründung. V olkmar G ropp . Der Einfluβ der Agrarreformen des beginnenden 19. Jahrhunderts in Ostpreuβen auf Höhe und usammensetzung der preuβischen Staatseinkünfte. G vrhakv A delmann (ed.).Dergewerblich‐industrielle Zustand der Rheinprovinz im Jahr 1836. Amtliche Übersichten. E dmund S ilberner. Moses Hess. Geschichte seines Lebens. H elmut B öhme. Deutschlands Weg zur Groβmacht. Studien zum Verkältnis von Wirtschaft und Staat währendderReichsgrundungszeit, 1848‐1881. C lemens B ruckner. Zur Wirtschaftsgesckichte des Regierungsbezirks Aachen. F ritz V. G runfeld . Das Leinenhaus Grünfeld. Erirmerungen und Dokumente. Eingeleitet und hrsg. von Stefi Jersch‐Wenzel. M arlies K utz . Zur Geschichte der Moselkanalisierung von den Anfängen bis zur Gegenwart, ein Überblick; G ertrud M ilkereit . Das Projekt der Moselkanalisierung, ein Problem der westdeutschen Eisen‐ und Stahlindustrie. D ieter L indenlaub. Richtungskämpfe im Verein für Sozialpolitik. Wissenschaft und Sozialpolitik im Kaiserreich vornehmlich vom Beginn des “Neuen Runes” bis zum Ausbruch des Ersten Weltkrieges, 1890‐1914. G erhard E rdmann . Die Deutschen Arbeitgeberverbände im sozialgeschichtlichen Wandel der Zeit. C hristiane K lapisch ‐Z uber . Les maǐtres du marbre: Carrare 1300‐1600. D avid B uisseret . Sully and the Growth of Centralized Government in France, 1598‐1610. R ené G andilon . Naissance du Champagne: Dom Pierre Pérignon. J. D upǎquier , M. L achiver , and J. M euvret . Mercuriales dupays de France et du Vexin frančais (1640‐1792). P. G oubert . Cent mille provinciaux au XVIIe Stèele. P. G oubert . Ľ'Ancien Régime. Vol. 1: La Société. Ľ Industrie frangaise au XVIIIe Stèele‐Pindustrie lainière à la fin du règne de Louis XIV et sous la Régence. Economies et Sociétés, Histoire quantitative de ľéconomie frančaise. A rthur H ertzberg. The French Enlightenment and the Jews. G eorge W eulersse. Le Mouvement physiocratique en France de 1756 à. 1770. A nne Z ink . Azereix. La vie ? une communauté rurale à la fin du XVIIIe siècle. J esus I barrola . Structure sociale et fortune mobileère a Grenoble en 1847. M. D aclin . La Crise des Années 30 à Besançon.

Book Reviews in This Article: R. H. H ilton . A Medieval Society: the West Midlands at the End of the Thirteenth Century . R. I. J ack (Ed.). The Grey of Ruthin Valor. The Valor of the English lands of Edmund Grey, Earl of Kent, drawn up from the ministers’ accounts of 1467‐8 . R oger H owell . Newcastle upon Tyne and the Puritan Revolution. A Study of the Civil War in North England . J. D. M arshall (Ed.). The Autobiography of William Stout of Lancaster 1665‐1752 . N aomi R iches . The Agricultural Revolution in Norfolk . F rank B ooker . Industrial Archaeology of the Tamar Valley . F rancis E. H yde with contributions from J. R. H arris and A. M. B ourn . Shipping Enterprise and Management, 1830‐1939: Harrisons of Liverpool . D avid L. S mith . The Dalmellington Iron Company. Its Engines and Men . J. R. V incent . Pollbooks: How Victorians Voted . M aurice C owling . 1867: Disraeli, Gladstone, and Revolution. The Passing of the Second Reform Bill . E. D. M ackerness (Ed.). The Journals of George Sturt, 1890‐1927 . B entley B. G ilbert . The Evolution of National Insurance in Great Britain. The Origins of the Welfare State . A. T. K. G rant . A Study of the Capital Market in Britain from 1919‐36 . W alford J ohnson , J ohn W hyman , G eorge W ykes . A Short Economic and Social History of Twentieth Century Britain . PERIODICAL LITERATURE, 1966 (i) Medieval (ii) 1500‐1700 (iii) 1700‐1800 (iv) Since 1800 P hilip G rierson . Bibliographie Numismatique . A. F errer . The Argentine Economy. An Economic History of Argentina . J. H ovy . Het voorstel van 1751 tot instelling van een bepeskt vrijhavenstelsel in de Republick . T heo P. M. de J ong . De krimpende horizon van de Hollandse kooplieden. Hollands welvaren in het Caribisch zeegebied, 1780‐1830 . G. L. A dhya . Early Indian Economics. Studies in the Economic Life of Northern and Western India 200 B.C. to A.D. 300 . T. H. B eaglehole . Thomas Munro and the Development of Administrative Policy in Madras, 1792‐1818 . K arl P olanyi . Dahomey and the Slave Trade. An Analysis of an Archaic Economy . R. J. H ammond . Portugal and Africa, 1815‐1910 . R oland O liver and A nthony A tmore . Africa since 1800 . C. R. B oxer . Portuguese Society in the Tropics. The Municipal Councils of Goa, Macao, Bahia, and Luanda, 1510‐1800 . GERMANY Beiträge zur Wirtschafts‐ und Stadtgeschichte. Festschrift für Hektor Ammann . Festschrift Hermann Aubin zum 80. Geburtstag . Wirtschaft, Geschichte und Wirtschaftsgeschichte. Festschrift zum 65. Geburtstag von Friedrich Lütge . F riedrich L utge . Die Agrarverfassung des frühen Mittelalters im mitteldeutschen Raum vornehmlich in der Karolingerzeit . P hilippe D ollinger . Die Hanse . K arl ‐F riedrich O lechnowitz . Handel und Seeschiffahrt der späten Hanse . W ilhelm A bel . Agrarkrisen und Agrarkonjunktur. Eine Geschichte der Land‐ und Ernährungs‐wirtschaft Mitteleuropas seit dent hohen Mittelalter . M artin G rosser . Anleitung zu der Landwirtschaft . W alter A chilles . Vermögensverhältnisse braunschweigischer Bauernhöfe im 17. und 18. Jahrhundert . C arl J antke and D ietrich H ilger (Eds.). Die Eigentumslosen. Der deutsche Pauperismus und die Emanzipationskrise in Darstellungen und Deutungen der zeitgenössischen Literatur . A ntje K raus . Die Unterschichten Hamburgs in der ersten Hälfte des 19. Jahrhunderts. Entstehung, Struktur und Lebensverhältnisse . E rnst W olfgang B uchholz . Ländliche Bevölkerung an der Schwelle des Industriezeitalters. Der Raum Braunschweig als Beispiel . I lja M ieck . Preussische Gewerbepolitik in Berlin, 1806‐1844. Staatshilfe und Privatinitiative zwischen Merkantilismus und Liberalismus . J ulius M arx . Die wirtschaftlichen Ursachen der Revolution von 1848 in Österreich . A lfred S chröter and W alter B ecker . Die deutsche Maschinenbauindustrie in der industriellen Revolution . H orst B lumberg . Die deutsche Textilindustrie in der industriellen Revolution . L udwig P uppke . Sozialpolitik und soziale Anschauungen frühindustrieller Unternehmer in Rheinland‐Westfalen . F ranz D ecker . Die betrieblich Sozialordnung der Dürener Industrie im 19. Jahrhundert . W olfram F ischer . Herz des Reviers. 125 Jahre Wirtschaftsgeschichte des Industrie‐ und Handelskammerbezirks Essen‐Mülheim‐Oberhausen . W alther G. H offmann , with the help of F ranz G rumbach and H elmut H esse . Das Wachstum der deutschen Wirtschaft seit der Mitte des 19. Jahrhunderts . R olf E ngelsing . Massenpublikum und Journalistentum im 19. Jahrhundert in Nordwestdeutschland . D ieter S chäfer . Der Deutsche Industrie‐ und Handelstag als politisches Forum der Weimarer Republik. Eine historische Studie zum Verhältnis von Politik und Wirtschaft . J ürgen K uczynski . Die Geschichte der Lage der Arbeiter unter dem Kapitalismus . Problemi delta civiltà e dell’ economia longobarda. Scritti in memoria di Gian Piero Bognetti . Annali dell’ Istituto di Storia Economica e Sociale dell’ Università di Napoli . G iuseppe G alasso . Mezzogiorno medievale e moderno . E lio C onti . La formazione della struttura agraria moderna nel contado fiorentino . A ngelo V entura . Nobiltà e popolo nella società veneta del ‘400 e'500 . M aria B orgherini . L'Arte della lana in Padova duranle il governo della Repubblica di Venezia, 1405‐1797 . M arino B erengo . Nobili e mercanti nella Lucca del Cinquecento . G. B elloni . Scritture inedite e dissertazioni “Del Commercio” . M ario B andini . Incontro con gli scrittori italiani di politica agraria—dalla metà del Settecento alla metà dell’ Ottocento . Insegnamenti di agricoltura parmigiana del XVIII secolo . L uigi D al P ane . La finanza toscana dagli inizi del secolo XVIII alla caduta del Granducato . C arlo V anzetti . Due secoli di storia dell’ agricoltura Veronese . P asquale V illani . La vendita dei beni dello stato nel regno di Napoli (1806‐1815) . D omenico D emarco . Banco, e congiuntura nel Mezzogiorno d'Italia . P iero B arucci . Il pensiero economico di Melchiorre Gioia . L uigi D e R osa . Il Banco di Napoli nella vita economica nazionale, 1863‐1883 . G iorgio P orisini . L'agricoltura ravennate nell’ età giolittiana. Prime ricerche . G iuseppe A re . Il problema dello sviluppo industriale nell’ età della Destra . PERIODICAL LITERATURE, 1966 P hilippe D ollinger and P hilippe W olff . Bibliographie d'histoire des villes de France . P ierre C haunu . La Civilisation de l'Europe Classique . M ichel M orineau . Jauges et méthodes de jauge anciennes et modernes . Annuaire statistique de la France, 1966 . Villages désertés et histoire économique. XI‐XVIII siècle . R obert B outruche (Ed.). Bordeaux de 1453 à 1715 . M ichel M ollat and P aul A dam . Les aspects internationaux de la découverte océanique aux XVe et XVIe siècles . E mmanuel L e R oy L adurie . Les Paysans du Languedoc . F. M auro . Le XVIe siècle européen. Aspects économiques . J. B ertin , S. B onin , P. C haunu . Les Philippines et le Pacifique des Ibériques, XVIe, XVIIe, XVIIIe siècles. Construction graphique . G aston R ambert . Histoire du Commerce de Marseille . P ierre G oubert . Louis XIV et vingt millions de Français . F erreol R ebuffat and M arcel C ourdurie . Marseille et le négoce monétaire international (1785‐1790) . A lbert S ilbert . Le Portugal méditerranéen à la fin de l'Ancien Régime. XVIIIe‐début du XIXe siècle. Contribution à l'histoire agraire comparée . A bel P oitrineau . La vie rurale en Basse‐Auvergne au XVIIIe siècle (1726‐1780) . J ean M eyer . La Noblesse bretonne au XVIIIe siècle . T. J. M arkovitch . L'industrie française de 1789 à 1964. Analyse des faits . J acques T oulemonde . Naissance d'une métropole. Histoire économique et sociale de Roubaix et Tourcoing au XIXe siècle . R oger P riouret . La Caisse des dépǒts. Cent‐cinquante ans d'histoire financière . J ean B ouvier , F rançois F uret , and M arcel G illet . Le mouvement du profit en France au XIXe siècle, Matériaux et Etudes . Modern History since 1500: (a) Rural (b) Non‐rural

Book Reviews in This Article: H. P. R. Finberg and V. H. T. Skipp. Local History: Objective and Pursuit. J. S. Cockburn, H. P. F. King, and K. G. T. McDonnell (Eds). A History of the County of Middlesex, vol. i. Victoria History of the Counties of England. A. T. Gaydon (Ed.). A History of the County of Shropshire, vol. VIII. Victoria History of the Counties of England. G. R. Elvey (Ed.). Luffield Priory Charters. Part 1. J. Z. Titow. English Rural Society, 1200‐1350. Joyce Youings. Tuckers Hall, Exeter: the History of a Provincial City Company through Five Centuries. James E. Oxley. The Fletchers and Longbowstringmakers of London. G. G. Cruickshank. Army Royal: an Account of Henry VIII's Invasion of France, 1513. R. B. Outhwaite. Inflation in Tudor and Early Stuart England. Edwin Welch (Ed.). The Admiralty Court Book of Southampton, 1566‐1585. Shelagh Bond (Ed.). The First Hall Book of the Borough of Mew Windsor, 1653‐1J25. H. E. S. Fisher (Ed.). The South‐West and the Sea. Exeter Papers in Economic History, no. 1. L. M. Cullen. Anglo‐Irish Trade 1660‐1800. Peter Mathias. The First Industrial Nation: An Economic History of Britain,1700‐1914 D. F. McKenzie and J. G. Ross (Eds.). A Ledger of Charles Ackers, Printer of the London Magazine. Frances Norton Mason (Ed.). John Morton & Sons, Merchants of London and Virginia. D. E. Varley. John Heathcoat, 1783‐1861, Founder of the Machine‐Made Lace Industry. W. O. Henderson. Industrial Britain under the Regency 1814‐18: The Diaries of Escher, Bodmer, May andde Gallois. Duncan Bythell. The Handloom Weavers. A Study in the English Cotton Industry during the Industrial Revolution. Charles Wing. The Evils of the Factory System. John R. Kellett. The Impact of Railways on Victorian Cities. D. I. Gordon. A Regional History of the Railways of Great Britain. Vol. v: The Eastern Counties. M. G. Reed (Ed.). Railways in the Victorian Economy. Studies in Finance and Economic Growth. Charles E. Raven. Christian Socialism, 1848‐1854. Ian MacDougall (Ed.). The Minutes of Edinburgh Trades Council, 1859‐1873. A Century of Agricultural Statistics: Great Britain, i866‐ig66. L. Napolitan. The Centenary of the Agricultural Census. Ronald George Garnett. A Century of Co‐operative Insurance: The Co‐operative Insurance Society, i86y‐ig6y: A Business History. Henry Pelling. Popular Politics and Society in Late Victorian Britain. S. B. Saul. The Myth of the Great Depression, 1873‐18g6. Studies in Economic History. Derek H. Aldcroft. British Railways in Transition: The Economic Problems of Britain's Railways since 1914. John Hibbs. The History of British Bus Services. J. Gilchrist. The Church and Economic Activity in the Middle Ages. C. G. F. Simkin. The Traditional Trade of Asia. Ralph Lee Woodward, Jr. Class Privilege and Economic Development. The Consulado de Comercio of Guatemala, 1793‐1871. R. A. Humphreys. Tradition and Revolt in Latin America, and other essays. W. O. Henderson. The Industrialisation of Europe, ij8o‐igi4. E. R.J. Owen. Cotton andthe Egyptian Economy’, 1820‐1914. A Study in Trade and Development. Robert Greenhalgh Albion. Naval and Maritime History: An Annotated Bibliography. 3rd edn, 2nd suppl. 1966‐8. E. H. Phelps Brown with Margaret H. Browne. A Century of Pay. The Course of Pay and Production in France, Germany, Sweden, the United Kingdom and the United States of America, i86a‐196o. Heinrich Bechtel. Wirtschqfts‐ und Sozialgeschichte Deutschlands: Wirtschaftsstile und Lebensformen von der VorzeitbiszurGegenwart. Ulf Dirlmeier. Mittelalterliche Hoheitsträgerim wirtschaftlichen Wettbewerb. Wilhelm Abel. Geschichte der deutschen Landwirtschaft vomfruhen Mittelalter bis zum 19. Jahrhundert. 2nd edn. Friedrich Lütge. Geschichte der deutschen Agrarver fassung vom frühen Mittelalter bis zum 19. Jahrhundert. 2nd edn. Eva‐Maria Engel and Benedykt Zientara. Feudalstruktur, Lehnbürgertum und Fernhandel im spätmittelalterlichen Brandenburg. Mit einer Einleitung von Eckhard Müller‐Mertens. Hartmut Schiele and Manfred Ricker. Betriebswirtschaftliche Aufschliisse aus der Fuggerzeit. Edith Schmitz. Leinengewerbe und Leinenhandel in Nordwestdeutschland, 1650‐1850. Jürgen Kuczynski. Das Entstehen der Arbeiterklasse. Hermann Kellenbenz. Die Zuckerwirtschqft im Kölner Raum von der napoleonischen Zeit bis zur Reichsgründung. Volkmar Gropp. Der Einfluβ der Agrarreformen des beginnenden 19. Jahrhunderts in Ostpreuβen auf Höhe und usammensetzung der preuβischen Staatseinkünfte. Gvrhakv Adelmann (ed.).Dergewerblich‐industrielle Zustand der Rheinprovinz im Jahr 1836. Amtliche Übersichten. Edmund Silberner. Moses Hess. Geschichte seines Lebens. Helmut Böhme. Deutschlands Weg zur Groβmacht. Studien zum Verkältnis von Wirtschaft und Staat währendderReichsgrundungszeit, 1848‐1881. Clemens Bruckner. Zur Wirtschaftsgesckichte des Regierungsbezirks Aachen. Fritz V. Grunfeld. Das Leinenhaus Grünfeld. Erirmerungen und Dokumente. Eingeleitet und hrsg. von Stefi Jersch‐Wenzel. Marlies Kutz. Zur Geschichte der Moselkanalisierung von den Anfängen bis zur Gegenwart, ein Überblick; Gertrud Milkereit. Das Projekt der Moselkanalisierung, ein Problem der westdeutschen Eisen‐ und Stahlindustrie. Dieter Lindenlaub. Richtungskämpfe im Verein für Sozialpolitik. Wissenschaft und Sozialpolitik im Kaiserreich vornehmlich vom Beginn des “Neuen Runes” bis zum Ausbruch des Ersten Weltkrieges, 1890‐1914. Gerhard Erdmann. Die Deutschen Arbeitgeberverbände im sozialgeschichtlichen Wandel der Zeit. Christiane Klapisch‐Zuber. Les maǐtres du marbre: Carrare 1300‐1600. David Buisseret. Sully and the Growth of Centralized Government in France, 1598‐1610. René Gandilon. Naissance du Champagne: Dom Pierre Pérignon. J. Dupǎquier, M. Lachiver, and J. Meuvret. Mercuriales dupays de France et du Vexin frančais (1640‐1792). P. Goubert. Cent mille provinciaux au XVIIe Stèele. P. Goubert. Ľ'Ancien Régime. Vol. 1: La Société. Ľ Industrie frangaise au XVIIIe Stèele‐Pindustrie lainière à la fin du règne de Louis XIV et sous la Régence. Economies et Sociétés, Histoire quantitative de ľéconomie frančaise. Arthur Hertzberg. The French Enlightenment and the Jews. George Weulersse. Le Mouvement physiocratique en France de 1756 à. 1770. Anne Zink. Azereix. La vie ? une communauté rurale à la fin du XVIIIe siècle. Jesus Ibarrola. Structure sociale et fortune mobileère a Grenoble en 1847. M. Daclin. La Crise des Années 30 à Besançon.