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11 result(s) for "Trimble, Will"
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The khmer software package: enabling efficient nucleotide sequence analysis version 1; peer review: 2 approved, 1 approved with reservations
The khmer package is a freely available software library for working efficiently with fixed length DNA words, or k-mers. khmer provides implementations of a probabilistic k-mer counting data structure, a compressible De Bruijn graph representation, De Bruijn graph partitioning, and digital normalization. khmer is implemented in C++ and Python, and is freely available under the BSD license at  https://github.com/dib-lab/khmer/.
Science-Driven Optimization of the LSST Observing Strategy
The Large Synoptic Survey Telescope is designed to provide an unprecedented optical imaging dataset that will support investigations of our Solar System, Galaxy and Universe, across half the sky and over ten years of repeated observation. However, exactly how the LSST observations will be taken (the observing strategy or \"cadence\") is not yet finalized. In this dynamically-evolving community white paper, we explore how the detailed performance of the anticipated science investigations is expected to depend on small changes to the LSST observing strategy. Using realistic simulations of the LSST schedule and observation properties, we design and compute diagnostic metrics and Figures of Merit that provide quantitative evaluations of different observing strategies, analyzing their impact on a wide range of proposed science projects. This is work in progress: we are using this white paper to communicate to each other the relative merits of the observing strategy choices that could be made, in an effort to maximize the scientific value of the survey. The investigation of some science cases leads to suggestions for new strategies that could be simulated and potentially adopted. Notably, we find motivation for exploring departures from a spatially uniform annual tiling of the sky: focusing instead on different parts of the survey area in different years in a \"rolling cadence\" is likely to have significant benefits for a number of time domain and moving object astronomy projects. The communal assembly of a suite of quantified and homogeneously coded metrics is the vital first step towards an automated, systematic, science-based assessment of any given cadence simulation, that will enable the scheduling of the LSST to be as well-informed as possible.
4 lockdowns disrupt classes at area schools
The Volusia County Sheriff's Office's bomb squad responded and discovered that this threat, like the one that caused a Wednesday afternoon lockdown at Seabreeze High School, was idle. The box contained clothing, according to Daytona Beach Police spokesman Jimmy Flynt. You have 1,000 parents out here. Someone should have come out here and said something,\" said [Crystal Virgil], who only knew the cause of the lockdown because her husband had called her. \"My daughter is always hungry when she gets home from school, and I know they haven't given her a snack in there.\" It's just a precaution to keep students and staff safe,\" [Nancy Wait] said. \"They stay in the classrooms where they are and no one is permitted into or out of the school.\"
Some new names, some old qualify for local elections
It was a good week overall for Candace Lankford. On Thursday, she was installed as president of the Florida School Boards Association. A day later, she won re-election to a third term when no one qualified to challenge her for the District 1 seat representing DeLand and Northwest Volusia. \"I was very surprised I did not have opposition,\" said Lank- ford, who also ran unopposed four years ago. \"I think it's a combination of good fortune and hard work.\" District 3 School Board incumbent Stan Schmidt wasn't as lucky, picking up a previously unannounced second challenger on the last day of qualifying. She is Sharon Luebbers of New Smyrna Beach, who will face off with Schmidt and Maredy Hanford, both of Port Orange, in an Aug. 24 primary in Southeast Volusia. A runoff will be scheduled Nov. 2 if no one gets more than half the primary vote. The District 3 race was set to elect a new council member as well, until [Alexander] decided to file Thursday. She's running as a pseudo-incumbent for the seat Jack Hayman is vacating due to term limits against Ellen Darden, William Benedict, Deborah Denys, Roger Gray, George Trovato, and another political newcomer, John D'Hondt.