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"Wislocki, Katherine"
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Comparing Generative Artificial Intelligence and Mental Health Professionals for Clinical Decision-Making With Trauma-Exposed Populations: Vignette-Based Experimental Study
2025
Trauma exposure is highly prevalent and associated with various health issues. However, health care professionals can exhibit trauma-related diagnostic overshadowing bias, leading to misdiagnosis and inadequate treatment of trauma-exposed populations. Generative artificial intelligence (GAI) models are increasingly used in health care contexts. No research has examined whether GAI demonstrates this bias in decision-making and how rates of this bias may compare to mental health professionals (MHPs).
This study aimed to assess trauma-related diagnostic overshadowing among frontier GAI models and compare evidence of trauma-related diagnostic overshadowing between frontier GAI models and MHPs.
MHPs (N=232; mean [SD] age 43.7 [15.95] years) completed an experimental paradigm consisting of 2 vignettes describing adults presenting with obsessive-compulsive symptoms or substance abuse symptoms. One vignette included a trauma exposure history (ie, sexual trauma or physical trauma), and one vignette did not include a trauma exposure history. Participants answered questions about their preferences for diagnosis and treatment options for clients within the vignettes. GAI models (eg, Gemini 1.5 Flash, ChatGPT-4o mini, Claude Sonnet, and Meta Llama 3) completed the same experimental paradigm, with each block being reviewed by each GAI model 20 times. Mann-Whitney U tests and chi-square analyses were used to assess diagnostic and treatment decision-making across vignette factors and respondents.
GAI models, similar to MHPs, demonstrated some evidence of trauma-related diagnostic overshadowing bias, particularly in Likert-based ratings of posttraumatic stress disorder diagnosis and treatment when sexual trauma was present (P<.001). However, GAI models generally exhibited significantly less bias than MHPs across both Likert and forced-choice clinical decision tasks. Compared to MHPs, GAI models assigned higher ratings for the target diagnosis and treatment in obsessive-compulsive disorder vignettes (rb=0.43-0.63; P<.001) and for the target treatment in substance use disorder vignettes (rb=0.57; P<.001) when trauma was present. In forced-choice tasks, GAI models were significantly more accurate than MHPs in selecting the correct diagnosis and treatment for obsessive-compulsive disorder vignettes (χ²1=48.84-61.07; P<.001) and for substance use disorder vignettes involving sexual trauma (χ²1=15.17-101.61; P<.001).
GAI models demonstrate some evidence of trauma-related diagnostic overshadowing bias, yet the degree of bias varied by task and model. Moreover, GAI models generally demonstrated less bias than MHPs in this experimental paradigm. These findings highlight the importance of understanding GAI biases in mental health care. More research into bias reduction strategies and responsible implementation of GAI models in mental health care is needed.
Journal Article
Implementing a resilience coach program to support first year housestaff during the COVID-19 pandemic: early pilot results and comparison with non-housestaff sessions
by
Wislocki, Katherine
,
Bellini, Lisa
,
Livesey, Cecilia
in
Analysis
,
Anxiety
,
Comparative analysis
2023
Background
In response to the COVID-19 pandemic, we launched the Penn Medicine Coping First Aid program to provide psychosocial supports to our health system community. Our approach leveraged lay health worker volunteers trained in principles of Psychological First Aid to deliver coaching services through a centralized virtual platform.
Methods
We emailed all (
n
= 408) first year housestaff (i.e., residents and fellows) with an invitation to schedule a session with a resilience coach. We compared the mental health concerns, symptoms, and Psychological First Aid techniques recorded in (
n
= 67) first year housestaff sessions with (
n
= 91) sessions of other employees in the health system.
Results
Between June and November 2020, forty-six first year housestaff attended at least one resilience coaching session. First year housestaff most commonly presented with feelings of anxiety and sadness and shared concerns related to the availability of social support. Resilience coaches most frequently provided practical assistance and ensured safety and comfort to first year housestaff. First year housestaff reported fewer physical or mental health symptoms and held shorter sessions with resilience coaches than non-housestaff.
Conclusions
This work offers insights on how to address psychosocial functioning through low-intensity interventions delivered by lay personnel. More research is needed to understand the efficacy of this program and how best to engage housestaff in wellness and resilience programs throughout training, both during and beyond COVID-19.
Journal Article
Freely Available Training Videos for Suicide Prevention: Scoping Review
by
Wislocki, Katherine
,
Becker-Haimes, Emily
,
Schaechter, Temma
in
Certification
,
Education
,
Educational films
2023
Freely available and asynchronous implementation supports can reduce the resource burden of evidence-based practice training to facilitate uptake. Freely available web-based training videos have proliferated, yet there have been no efforts to quantify their breadth, depth, and content for suicide prevention.
This study presents results from a scoping review of freely available training videos for suicide prevention and describes a methodological framework for reviewing such videos.
A scoping review of freely available training videos (≥2 minutes) for suicide prevention practices was conducted using 4 large video-sharing platforms: YouTube, Vimeo, Bing Video, and Google Video. Identified suicide prevention training videos (N=506) were reviewed and coded.
Most content was targeted toward gatekeepers or other lay providers (n=370) versus clinical providers (n=136). Videos most commonly provided content related to suicidal thoughts or behaviors (n=420). Many videos (n=274, 54.2%) included content designed for certain communities or organizations. Less than half (n=232, 45.8%) of training videos included formal clinical content pertaining to assessment or intervention for suicide prevention.
Results suggested an abundance of videos providing broad informational content (eg, \"signs and symptoms of someone at risk for suicide\") and a limited portion of videos with instructional content aimed at clinical providers delivering formal evidence-based assessments or interventions for suicide prevention. Development of resources to address identified gaps may be needed. Future work may leverage machine learning techniques to expedite the review process.
Journal Article
The Past, Present, and Future of Psychotherapy Manuals: Protocol for a Scoping Review
by
Wislocki, Katherine
,
Cenkner, David
,
Zalta, Alyson K
in
Bibliographic records
,
Bibliometrics
,
Citation management software
2023
Psychotherapy manuals are critical to the dissemination of psychotherapy treatments. Psychotherapy manuals typically serve several purposes, including, but not limited to, establishing new psychotherapy treatments, training providers, disseminating treatments to those who deliver them, and providing guidelines to deliver treatments with fidelity. Yet, the proliferation of psychotherapy manuals has not been well-understood, and no work has aimed to assess or review the existing landscape of psychotherapy manuals. Little is known about the breadth, scope, and foci of extant psychotherapy manuals.
This scoping review aims to identify and explore the landscape of existing book-based psychotherapy manuals. This review aims to specify the defining characteristics (ie, foci, clinical populations, clinical targets, treatment type, treatment modality, and adaptations) of existing book-based psychotherapy manuals. Further, this review will demonstrate how this information, and psychotherapy manuals more broadly, has changed over time. This project aims to make a novel contribution that will have critical implications for current methods of developing, aggregating, synthesizing, and translating knowledge about psychotherapeutic treatments.
This scoping review will review book-based psychotherapy manuals published from 1950 to 2022.This scoping review will be informed by guidance from the Joanna Briggs Institute Scoping Review Methodology Group and prior scoping reviews. Traditional search and application programming interface-based search methods will be used with search terms defined a priori to identify relevant results using 3 large book databases: Google Books, WorldCat, and PsycINFO. This review will leverage machine learning methods to enhance and expedite the screening process. Primary screening of results will be conducted by at least 2 authors. Data will be extracted and double-coded by research assistants using an iteratively defined codebook.
The search process produced 78,600 results, which were then iteratively deduplicated. Following deduplication, 50,583 results remained. The scoping review is expected to identify common elements of psychotherapy manuals, establish how the foci and content of manuals have changed over time, and illustrate coverage and gaps in the landscape of psychotherapy manuals. Results from this scoping review will be critical for future work focused on developing, aggregating, synthesizing, and disseminating knowledge about psychotherapeutic treatments.
This review will provide knowledge about the vast landscape of psychotherapy manuals that exist. Findings from this study will inform future efforts to develop, aggregate, synthesize, and translate knowledge about psychotherapeutic treatments.
DERR1-10.2196/47708.
Journal Article
Assessing Causal Pathways and Targets of Implementation Variability for EBP use (Project ACTIVE): a study protocol
by
Wislocki, Katherine
,
Reich, Danielle
,
Williams, Nathaniel J.
in
Behavior change theory
,
Causal model
,
Cognitive-behavioral therapy
2021
Background
Advancing causal implementation theory is critical for designing tailored implementation strategies that target specific mechanisms associated with evidence-based practice (EBP) use. This study will test the generalizability of a conceptual model that integrates organizational constructs and behavioral theory to predict clinician use of cognitive-behavioral therapy (CBT) techniques in community mental health centers. CBT is a leading psychosocial EBP for psychiatric disorders that remains underused despite substantial efforts to increase its implementation.
Methods
We will leverage ongoing CBT implementation efforts in two large public health systems (Philadelphia and Texas) to recruit 300 mental health clinicians and 600 of their clients across 40 organizations. Our primary implementation outcomes of interest are clinician intentions to use CBT and direct observation of clinician use of CBT. As CBT comprises discrete components that vary in complexity and acceptability, we will measure clinician use of six discrete components of CBT. After finishing their CBT training, participating clinicians will complete measures of organizational and behavior change constructs delineated in the model. Clinicians also will be observed twice via audio recording delivering CBT with a client. Within 48 h of each observation, theorized moderators of the intention-behavior gap will be collected via survey. A subset of clinicians who report high intentions to use CBT but demonstrate low use will be purposively recruited to complete semi-structured interviews assessing reasons for the intention-behavior gap. Multilevel path analysis will test the extent to which intentions and determinants of intention predict the use of each discrete CBT component. We also will test the extent to which theorized determinants of intention that include psychological, organizational, and contextual factors explain variation in intention and moderate the association between intentions and CBT use.
Discussion
Project ACTIVE will advance implementation theory, currently in its infancy, by testing the generalizability of a promising causal model of implementation. These results will inform the development of implementation strategies targeting modifiable factors that explain substantial variance in intention and implementation that can be applied broadly across EBPs.
Journal Article
Implementing nudges for suicide prevention in real-world environments: project INSPIRE study protocol
by
Mautone, Jennifer A.
,
Marx, Darby
,
Mandell, David S.
in
Behavior
,
Behavioral economics
,
Behavioral medicine
2020
Background
Suicide is a global health issue. There are a number of evidence-based practices for suicide screening, assessment, and intervention that are not routinely deployed in usual care settings. The goal of this study is to develop and test implementation strategies to facilitate evidence-based suicide screening, assessment, and intervention in two settings where individuals at risk for suicide are especially likely to present: primary care and specialty mental health care. We will leverage methods from behavioral economics, which involves understanding the many factors that influence human decision making, to inform strategy development.
Methods
We will identify key mechanisms that limit implementation of evidence-based suicide screening, assessment, and intervention practices in primary care and specialty mental health through contextual inquiry involving behavioral health and primary care clinicians. Second, we will use contextual inquiry results to systematically design a menu of behavioral economics-informed implementation strategies that cut across settings, in collaboration with an advisory board composed of key stakeholders (i.e., behavioral economists, clinicians, implementation scientists, and suicide prevention experts). Finally, we will conduct rapid-cycle trials to test and refine the menu of implementation strategies. Primary outcomes include clinician-reported feasibility and acceptability of the implementation strategies.
Discussion
Findings will elucidate ways to address common and unique barriers to evidence-based suicide screening, assessment, and intervention practices in primary care and specialty mental health care. Results will yield refined, pragmatically tested strategies that can inform larger confirmatory trials to combat the growing public health crisis of suicide.
Journal Article
Assessing the Existence of Trauma-Related Diagnostic Overshadowing in Adult Populations
2023
Previous research with youth has shown that clinicians tend to diagnose and treat post-traumatic stress disorder (PTSD) in trauma-exposed clients, even when clinical presentations indicate that PTSD is not the primary diagnosis. The current study sought to examine this trauma-related diagnostic overshadowing bias in adult cases across different types of trauma exposure. Mental health professionals (N = 232) reviewed two vignettes describing an adult seeking treatment for either obsessive-compulsive disorder (OCD) symptoms or substance use disorder (SUD) symptoms (target disorders). Each participant was randomly assigned to one vignette in which one client endorsed exposure to trauma (i.e., sexual trauma or physical trauma) and one vignette in which the client reported no trauma exposure. Following each vignette, participants responded to questions related to the diagnosis and treatment of the client. In both cases, participants were significantly less likely to choose the target diagnosis and treatment and more likely to choose a PTSD diagnosis and trauma treatment when trauma exposure was present in the vignettes. Evidence for the bias was strongest for vignettes that contained sexual trauma compared to vignettes that contained physical trauma. Evidence for the bias was also more consistent in the OCD case compared to the SUD case. Results indicate evidence for the existence of trauma-related diagnostic overshadowing in adult populations, though the strength of this bias may be dependent on aspects of the trauma and overall clinical presentation. More work is needed to understand factors that may impact the presence of this bias.
Dissertation
The Relationship Between Trauma Exposure and Obsessive–Compulsive Disorder in Youth: A Systematic Review
by
Wislocki, Katherine
,
Martin, Gerald
,
Kratz, Hilary E
in
Adults
,
Antisocial Behavior
,
Anxiety Disorders
2023
Extant literature suggests a possible relationship between childhood trauma exposure and the development and trajectory of obsessive–compulsive symptoms (OCS) and obsessive–compulsive disorder (OCD); however, this relationship is poorly understood. We conducted a systematic review that examined trauma exposure and OCS/OCD in youth. Primary inclusion criteria were English-language articles that addressed a sample with participants under 18 years of age. 46 articles met criteria for review, and were categorized into three groups of overlap: Post-traumatic Stress Disorder (PTSD) and OCS or OCD (n = 3), clearly defined Criterion A event trauma exposure and OCS or OCD (n = 30), and less well-defined potential trauma exposure and OCS or OCD (n = 13). There was mixed evidence linking trauma exposure and the development of OCS or OCD in youth. Major methodological limitations preclude formal conclusions. More research on co-occurring trauma exposure and OCD/OCS in youth is needed to advance research and improve treatment.
Journal Article
Preliminary Implementation Outcomes of a Free Online Toolkit to Support Exposure Therapy Implementation for Youth
2023
BackgroundExposure therapy (“exposure”) for youth anxiety is highly underutilized in clinical practice. Asynchronous, online implementation strategies such as online toolkits hold promise as pragmatic approaches for extending the sustainability of evidence-based interventions, but their long-term usage, perceived utility, and impact are rarely studied.ObjectiveThis study presents three-year preliminary implementation outcomes for a free, online toolkit to support exposure therapy use with youth: the Resource for Exposure for Anxiety Disordered Youth (READY; www.bravepracticeforkids.com). Implementation outcomes of interest included READY usage statistics, adoption, perceived utility, and clinician exposure use.MethodsWeb analytics characterized usage patterns. A survey of READY users (N = 49; M age = 34.2, 82.9% female, 71% White) assessed adoption, perceived utility, clinician exposure use, and persistent barriers to exposure use.ResultsIn its first three years, READY had 13,543 page views across 1,731 unique users; 442 (25.6%) registered as a site user to access specialized content. Survey data suggested variability in usage and perceived utility across toolkit components. Qualitative analyses highlighted persistent exposure barriers that pointed to potential READY refinements.ConculsionsOverall, READY has been accessed by hundreds of clinicians, but its impact was limited by low return to the site. This study highlights strengths and limitations of standalone online implementation supports and identifies additional steps needed to optimally support clinicians to deliver exposure to youth in need.
Journal Article