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Purpose The purpose of this study was to evaluate the clinical and optical coherence tomography (OCT) results of a newly proposed technique to treat chronic central serous chorioretinopathy (cCSR) and to determine its efficacy in cCSR treatment. This technique is termed photostatic treatment (PST). Study design A prospective study which includes 44 eyes of 38 patients were treated with PST and followed up for at least 24 months. Methods PST was performed by administering light energy delivered to the area using a 689 nm diode laser. PST was performed using the conventional fluence rate (60 J/cm 2 ) with a conventional irradiation time of 83 s. Each patient was treated with 3 consecutive laser applications. The primary outcome measures were complete resolution of subretinal fluid and improvement in best-corrected visual acuity (BCVA). Results The median central macular thickness (CMT) was significantly lower at the final visit after treatment than the initial presentation (median CMT 332,5µ versus 234µ, p  < 0.001). Complete resolution of the fluid at the last visit could be achieved in 31 (70.4%) eyes with a significant improvement in median BCVA ( p  < 0.001). Conclusion The application of laser treatment without a photosensitizing agent proved effective in controlling cCSR, and we propose the term ‘photostatic treatment’ for this new technique.

Purpose To present and compare the long-term results of Dr. Tamcelik’s previously described technique of Tenon advancement and duplication with the conventional Ahmed glaucoma valve (AGV) implantation technique in patients with refractory glaucoma. Methods This study was a multicenter, retrospective case series that included 303 eyes of 276 patients with refractory glaucoma who underwent glaucoma valve implantation surgery. The patients were divided into three groups according to the surgical technique applied and the outcomes compared. In group 1, 96 eyes of 86 patients underwent AGV implant surgery without patch graft; in group 2, 78 eyes of 72 patients underwent AGV implant surgery with donor scleral patch; in group 3, 129 eyes of 118 patients underwent Ahmed valve implant surgery with “combined short scleral tunnel with Tenon advancement and duplication technique”. The endpoint assessed was tube exposure through the conjunctiva. Results In group 1, conjunctival tube exposure was seen in 11 eyes (12.9 %) after a mean 9.2 ± 3.7 years of follow-up. In group 2, conjunctival tube exposure was seen in six eyes (2.2 %) after a mean 8.9 ± 3.3 years of follow-up. In group 3, there was no conjunctival exposure after a mean 7.8 ± 2.8 years of follow-up. The difference between the groups was statistically significant. ( P  = 0.0001, Chi-square test). Conclusion This novel surgical technique combining a short scleral tunnel with Tenon advancement and duplication was found to be effective and safe to prevent conjunctival tube exposure after AGV implantation surgery in patients with refractory glaucoma.

Purpose To study the efficacy of intravitreal bevacizumab (IVB) injection as a single treatment for retinopathy of prematurity (ROP). Methods This was a prospective interventional case series study performed in a clinical practice setting; a total of 122 patients including prethreshold (type 1) ( n   = 79, 152 eyes, six unilateral), threshold ( n  = 12, 24 eyes), and aggressive posterior (APROP) ( n  = 31, 62 eyes); cases were included without any randomization or masking. A total of 253 IVB injections, 238 in the first session, 11 in the second session, and four in the third session were performed, and followed up for a mean of 89.155 ± 4.277 (range 82 to 105) weeks of postmenstrual age (PMA). Regression of ROP, maturation of the retina, and associated complications were evaluated. Results Total regression was achieved in 227/238 eyes (95.4 %) after the first dose injection. The remaining 11 received a second injection, after which an additional seven (234/238; 98.2 %) regressed; after the third injection, the remaining 4 (238/238; 100 %) regressed. Complete retinal vascular maturation was achieved without any significant complications in all of the cases. Conclusions IVB injection as monotherapy seems to be a very effective treatment modality for ROP. Based on timely intervention, IVB as a single treatment modality can salvage almost all ROP cases before stage 4.

Purpose: To assess the outcome of scleral buckling surgery using a non-contact wide-angle viewing system for fundus visualization in patients with rhegmatogenous retinal detachment without proliferative vitreoretinopathy. Patients and Methods: Sixteen eyes of 16 patients underwent scleral buckling using a non-contact wide-angle viewing system combined with a 25-gauge illumination fibre inserted into the sclera at the pars plana. Results: The mean age of the patients was 53.6 ± 13.7 years and the mean follow-up time was 13.4 ± 2.8 months. Retinal reattachment was achieved in 13 of the 16 eyes (81%). Three eyes underwent vitrectomy with silicone oil injection because of development of proliferative vitreoretinopathy in 2 eyes and scleral perforation due to excessive indentation during cryoretinopexy in 1 eye. Two eyes developed limited subretinal haemorrhage during subretinal fluid drainage. Conclusion: Simultaneous use of a non-contact wide-angle viewing system combined with a 25-gauge light fibre illumination for fundus visualization brings the advantages of microsurgery and indirect ophthalmoscopy into scleral buckling surgery.

A 25-year-old man suffered an isolated lens anterior capsular tear and mature cataract formation following blunt injury to his right eye. One week after the trauma, best-corrected visual acuity (BCVA) in the right eye was hand motion. B-scan ultrasonography showed that the lens posterior capsule was intact; no vitreous foreign body or retinal pathology were observed. Orbital computed tomography revealed narrowed anterior chamber and increased lens material volume and lens reflectivity in the injured right eye. The globe was intact and no bone fractures were observed. The cataractous lens material was removed by phacoemulsification and a foldable, acrylic, posterior chamber intraocular lens was implanted in the bag. Postoperative BCVA in the right eye was 20/20. Keywords: Blunt eye trauma, lens anterior capsule rupture, traumatic cataract

Purpose: To study the incidence and risk factors of retinopathy of prematurity (ROP) in premature infants examined in a tertiary hospital in Istanbul. Methods: Data of infants screened for ROP from April 2007 to September 2009 were retrospectively reviewed. Possible risk factors and eye examinations were recorded and analyzed using the chi-square test and univariate and multivariate regressions. Results: ROP was detected in 177 (34.3%) of the 517 infants enrolled in the study; 64 had mild ROP (77.4%) and 38 had severe ROP (22.6%). The mean gestational age and birth weight of patients who were treated for ROP were 28.6 ± 2.3 and 1,143.5 ± 337.4, respectively. Two of these infants had a gestational age of 32 g or greater and three had a birth weight of 1,500 g or greater. The multivariate regression analyses showed gestational age, birth weight, sepsis, respiratory distress syndrome, and length of oxygen therapy as independent predictors of ROP. Conclusion: The incidence of ROP observed in this study was higher than that in developed countries and relatively more mature infants were affected. Criteria including gestational age of less than 34 weeks or birth weight of less than 2,000 g would have identified all infants who were at risk.

The purpose of the study is to evaluate the clinical outcome of laser photocoagulation (LPC) in the treatment of retinopathy of prematurity (ROP) at a referral hospital in Turkey. In this retrospective study, a chart review of infants who underwent LPC for ROP between June 2011 and June 2013 was done. Clinical and demographic characteristics, laser parameters, anatomic, and refractive outcomes were evaluated. Totally 113 infants (202 eyes) were enrolled in the study. Of the 202 eyes, 29 eyes had threshold ROP, 141 eyes had prethreshold ROP, and 32 eyes had aggressive posterior ROP (APROP) at initial interventions. The mean gestational age (GA) was 28.13 ± 1.99 weeks (range between 24 and 33 weeks), the mean birth weight (BW) was 1,147.77 ± 341.77 g (range between 530 and 2,000 g) and the mean postmenstrual age (PMA) at first laser treatment time was 35.79 ± 1.74 weeks (range between 33 and 39 weeks). The mean number of laser spots (NLS) applied for each eye was 1,358.05 ± 369.91. Eyes with APROP had higher number of NLS than eyes with threshold ROP and prethreshold ROP ( P  < 0.01). Anatomic outcome was favorable for 171 eyes (84.7 %) at the end of the 1-year follow-up. Refractive data were available for 56 infants (100 eyes). The mean refractive error was 0.00 ± 2.48D SE. The incidence of high myopia (>5D) and strabismus was 2 and 14.3 %, respectively. Laser photocoagulation is an effective therapy for ROP. Early and appropriate laser treatment improves the clinical outcome of the disease.

BACKGROUND AND OBJECTIVE: To present and evaluate a novel surgical technique to prevent exposure of the Ahmed valve implant tube (New World Medical, Rancho Cucamonga, CA) through conjunctiva in congenital glaucoma called “combined short scleral tunnel technique with Tenon advancement and duplication.” PATIENTS AND METHODS: Patients with failed previous congenital glaucoma surgeries were divided into two groups. In group 1, 32 eyes of 28 patients with a mean age of 8.82 ± 5.39 years underwent classic Ahmed valve implant surgery. In group 2, 28 eyes of 24 patients with a mean age of 8.79 ± 5.55 years underwent the novel combined short scleral tunnel with Tenon advancement and duplication technique. RESULTS: After a mean 31.68 ± 9.25 months of follow-up, conjunctival tube exposure was seen in 3 patients (9.4%) in group 1. There was no conjunctival tube exposure in group 2 after a mean 34.96 ± 7.93 months of follow-up. CONCLUSION: The combined short scleral tunnel with Tenon advancement and duplication technique is able to prevent conjunctival tube exposure after Ahmed valve implantation surgery in patients with congenital glaucoma. [Ophthalmic Surg Lasers Imaging 2010;41:370–374.]

To present and evaluate a novel surgical technique to prevent exposure of the Ahmed valve implant tube (New World Medical, Rancho Cucamonga, CA) through conjunctiva in congenital glaucoma called \"combined short scleral tunnel technique with Tenon advancement and duplication.\" Patients with failed previous congenital glaucoma surgeries were divided into two groups. In group 1, 32 eyes of 28 patients with a mean age of 8.82 +/- 5.39 years underwent classic Ahmed valve implant surgery. In group 2, 28 eyes of 24 patients with a mean age of 8.79 +/- 5.55 years underwent the novel combined short scleral tunnel with Tenon advancement and duplication technique. After a mean 31.68 +/- 9.25 months of follow-up, conjunctival tube exposure was seen in 3 patients (9.4%) in group 1. There was no conjunctival tube exposure in group 2 after a mean 34.96 +/- 7.93 months of follow-up. The combined short scleral tunnel with Tenon advancement and duplication technique is able to prevent conjunctival tube exposure after Ahmed valve implantation surgery in patients with congenital glaucoma.