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Exploring the inheritance and protection of folk music from the perspective of folklore is a modern transformation of the understanding paradigm of music anthropology and the comprehensive art model of Miao folk music, which integrates related disciplines and research fields. A more comprehensive and thorough display of the profound connotations of traditional Chinese music. It also deeply and extensively analyzes the historical and cultural value of folk music created by the people in their daily lives, the maintenance value of ecological culture protection, and the development value of social progress. Focusing on returning to life culture, reflecting the uniqueness of the nation, fusing the diverse national cultures, and demonstrating the human spirit of re-innovation are the principles of traditional music \"life protection\". In real life, the protection of folk music should pay special attention to the music activities of the inheritors. With the technical support of computer virtual reality software, place it in a specific time and space, and take advantage of regional differences to adopt diversified strategies.

DNA base modifications, such as C5-methylcytosine (5mC) and N6-methyldeoxyadenosine (6mA), are important types of epigenetic regulations. Short-read bisulfite sequencing and long-read PacBio sequencing have inherent limitations to detect DNA modifications. Here, using raw electric signals of Oxford Nanopore long-read sequencing data, we design DeepMod, a bidirectional recurrent neural network (RNN) with long short-term memory (LSTM) to detect DNA modifications. We sequence a human genome HX1 and a Chlamydomonas reinhardtii genome using Nanopore sequencing, and then evaluate DeepMod on three types of genomes ( Escherichia coli , Chlamydomonas reinhardtii and human genomes). For 5mC detection, DeepMod achieves average precision up to 0.99 for both synthetically introduced and naturally occurring modifications. For 6mA detection, DeepMod achieves ~0.9 average precision on Escherichia coli data, and have improved performance than existing methods on Chlamydomonas reinhardtii data. In conclusion, DeepMod performs well for genome-scale detection of DNA modifications and will facilitate epigenetic analysis on diverse species. DNA modification generates unique electric signals in Oxford Nanopore sequencing data but the signals can be complicated to decipher. Here, the authors develop a deep learning framework, DeepMod, to detect DNA base modifications including 5mC and 6mA using Nanopore sequencing data

For an ordinary ferroelectric, the magnitude of the spontaneous electric polarization is at least one order of magnitude smaller than that resulting from the ionic displacement of the lattice vectors, and the direction of the spontaneous electric polarization is determined by the point group of the ferroelectric. Here, we introduce a new class of ferroelectricity termed Fractional Quantum Ferroelectricity. Unlike ordinary ferroelectrics, the polarization of Fractional Quantum Ferroelectricity arises from substantial atomic displacements that are comparable to lattice constants. Applying group theory analysis, we identify 27 potential point groups that can realize Fractional Quantum Ferroelectricity, including both polar and non-polar groups. The direction of polarization in Fractional Quantum Ferroelectricity is found to always contradict with the symmetry of the “polar” phase, which violates Neumann’s principle, challenging conventional symmetry-based knowledge. Through the Fractional Quantum Ferroelectricity theory and density functional calculations, we not only explain the puzzling experimentally observed in-plane polarization of monolayer α-In 2 Se 3 , but also predict polarization in a cubic compound of AgBr. Our findings unveil a new realm of ferroelectric behavior, expanding the understanding and application of these materials beyond the limits of traditional ferroelectrics. A concept of fractional quantum ferroelectricity is proposed, where the direction of ferroelectric polarization difference no longer subjects to the symmetry restrictions of Neumann’s principle. It indicates that ferroelectricity can exist in nonpolar systems, which may lead to discovery of many overlooked ferroelectrics.

Realization of higher-order multistates with mutual interstate switching in ferroelectric materials is a perpetual drive for high-density storage devices and beyond-Moore technologies. Here we demonstrate experimentally that antiferroelectric van der Waals CuInP 2 S 6 films can be controllably stabilized into double, quadruple, and sextuple polarization states, and a system harboring polarization order of six is also reversibly tunable into order of four or two. Furthermore, for a given polarization order, mutual interstate switching can be achieved via moderate electric field modulation. First-principles studies of CuInP 2 S 6 multilayers help to reveal that the double, quadruple, and sextuple states are attributable to the existence of respective single, double, and triple ferroelectric domains with antiferroelectric interdomain coupling and Cu ion migration. These findings offer appealing platforms for developing multistate ferroelectric devices, while the underlining mechanism is transformative to other non-volatile material systems. Materials with higher-order multistates are desired for non-Boolean high-density storage. Here the authors realized sextuple intrinsic polarization states in vdW CuInP 2 S 6 , and reversible transformation among sextuple-, quadruple-, and double-polarization orders.

Depression is prevalent among older persons, which seriously threatens their life satisfaction. This study aimed to explore the internal mechanisms by which depression influences life satisfaction among the elderly, as well as the mediating and moderating effects of ostracism and economic income, respectively, in a sample of rural older adults across China. This was a cross-sectional survey conducted as part of the project “Thousands of People and Hundreds of Villages (2019).” Participants were rural older adults from 31 provincial-level administrative units across China. The sample composed of 1,754 participants aged 60 years and over. Depression was assessed with the depression subscale of the Depression Anxiety Stress Scales, life satisfaction with the Satisfaction with Life Scale, ostracism with the Ostracism Experience Scale (OES), and economic income and other control variables with related demographic scales. Moderation and mediation analyses were performed using the regression-based approach as conducted by Hayes (2013). Depression negatively predicted life satisfaction among the elderly. Ostracism played a partially mediating role between depression and life satisfaction. Economic income moderated the effect of depression and ostracism on life satisfaction: High economic income weakened the negative effect of depression on life satisfaction and enhanced the negative effect of ostracism on life satisfaction. Improving depressed elderly people’s interpersonal relationships and financial support could improve their life satisfaction.

State-of-the-art compact antennas rely on electromagnetic wave resonance, which leads to antenna sizes that are comparable to the electromagnetic wavelength. As a result, antennas typically have a size greater than one-tenth of the wavelength, and further miniaturization of antennas has been an open challenge for decades. Here we report on acoustically actuated nanomechanical magnetoelectric (ME) antennas with a suspended ferromagnetic/piezoelectric thin-film heterostructure. These ME antennas receive and transmit electromagnetic waves through the ME effect at their acoustic resonance frequencies. The bulk acoustic waves in ME antennas stimulate magnetization oscillations of the ferromagnetic thin film, which results in the radiation of electromagnetic waves. Vice versa, these antennas sense the magnetic fields of electromagnetic waves, giving a piezoelectric voltage output. The ME antennas (with sizes as small as one-thousandth of a wavelength) demonstrates 1–2 orders of magnitude miniaturization over state-of-the-art compact antennas without performance degradation. These ME antennas have potential implications for portable wireless communication systems. The miniaturization of antennas beyond a wavelength is limited by designs which rely on electromagnetic resonances. Here, Nan et al. have developed acoustically actuated antennas that couple the acoustic resonance of the antenna with the electromagnetic wave, reducing the antenna footprint by up to 100.

Maize is an important crop with a high level of genome diversity and heterosis. The genome sequence of a typical female line, B73, was previously released. Here, we report a de novo genome assembly of a corresponding male representative line, Mo17. More than 96.4% of the 2,183 Mb assembled genome can be accounted for by 362 scaffolds in ten pseudochromosomes with 38,620 annotated protein-coding genes. Comparative analysis revealed large gene-order and gene structural variations: approximately 10% of the annotated genes were mutually nonsyntenic, and more than 20% of the predicted genes had either large-effect mutations or large structural variations, which might cause considerable protein divergence between the two inbred lines. Our study provides a high-quality reference-genome sequence of an important maize germplasm, and the intraspecific gene order and gene structural variations identified should have implications for heterosis and genome evolution. The de novo genome assembly of maize line Mo17 and comparative analysis with other sequenced maize lines show extensive gene-order variations. This study provides insights into maize evolution and has implications for improving maize hybrid lines.

In this study, the bedform dimensions of an alluvial bed in a unidirectional flow were experimentally investigated. A series of flume experiments was conducted; 700 sets of flume and field data were used in developing formulae for predicting the bedform dimensions on alluvial beds in unidirectional flow. Bedform dimensions include the length and height of bedforms generated by the lower and upper flow regimes; the resistance coefficient for the flow in different flow regimes is introduced into the proposed formulae. The momentum boundary-layer thickness was introduced as an independent variable instead of the flow depth. Based on a large amount of flume and field data, the coefficients of each parameter were determined; four typical formulae were used to compare the accuracy of the proposed formulae. The experimental results show that the momentum boundary-layer thickness, hydraulic radius, and resistance coefficient for the flow in different regimes correlate well with the bedform dimensions. The calculation results show that the dimensionless particle size should not be ignored in the calculation of bedform dimensions. The bedform dimensions have an obvious trend of rapid increase with an increase in the ratio of flow depth to sand size (H/d). The bedform dimensions obtained using the van Rijn method and the Engelund and Hansen method did not represent the variation trend of the bedform length in the upper flow regime with an increase in H/d when H/d was greater than 103. The calculations using the proposed formulae are more accurate and reasonable than those in previous studies predicting the bedform height and length on an alluvial bed in a unidirectional flow.

Background Atractylodes macrocephala Koidz. is a medicinal plant in high clinical demand due to its pharmacological efficacy. However, research on its quality dynamics across different growth years remains limited, primarily focusing on transcriptomics, microbiome analysis, and photosynthetic capacity, with studies only extending to three-year-old plants. Results This study examines A. macrocephala over a broader growth span (1, 2, 3, 5, and 10 years), integrating morphological, microstructural, metabolomic, spatial metabolite distribution, and transcriptomic analyses. Morphologically, rhizome weight and length increased with age, and the characteristic “ Hejing ” structure became more pronounced. Microstructural analysis revealed progressively developed xylem. Metabolomic profiling indicated a decline in sucrose content, alongside increased accumulation of bioactive sesquiterpenoids and phenolic acids over time. Transcriptomic analysis showed that genes involved in the biosynthesis of these active compounds—terpenoid backbone ( HMGR , DXS , idi , GPS , and GGPS ), phenylpropanoid ( PAL , 4CL , and HCT ), and sucrose metabolism ( SPS and SPP )—were upregulated in older plants. Desorption electrospray ionisation mass spectrometry imaging (DESI-MSI) revealed an expanded distribution of key metabolites with increasing growth years. Conclusion The findings suggest that A. macrocephala aged 5 and 10 years exhibit superior quality, with a more distinct “ Hejing ” morphology and higher levels of bioactive compounds. The quality stabilises after five years, indicating that older plants may possess enhanced medicinal value.

Magnetoelectric (ME) sensors cannot effectively detect broadband magnetic field signals due to their narrow bandwidth, and existing readout circuits are unable to vary the bandwidth of the sensors. To expand the bandwidth, this paper introduces a negative-feedback readout circuit, fabricated by introducing a negative-feedback compensation circuit based on the direct readout circuit of the ME sensor. The negative-feedback compensation circuit contains a current amplifier, a feedback resistor, and a feedback coil. For this purpose, a Metglas/PVDF/Metglas ME sensor was prepared. Experimental measurements show that there is a six-fold difference between the maximum and minimum values of the ME voltage coefficients in the 6–39 kHz frequency band for the ME sensor without the negative-feedback compensation circuit when the sensor operates at the optimal bias magnetic field. However, the ME voltage coefficient in this band remains stable, at 900 V/T, after the charge amplification of the direct-reading circuit and the negative-feedback circuit. In addition, experimental results show that this negative-feedback readout circuit does not increase the equivalent magnetic noise of the sensor, with a noise level of 240 pT/√Hz in the frequency band lower than 25 kHz, 63 pT/√Hz around the resonance frequency of 30 kHz, and 620 pT/√Hz at 39 kHz. This paper proposes a negative-feedback readout circuit based on the direct readout circuit, which greatly increases the bandwidth of ME sensors and promotes the widespread application of ME sensors in the fields of broadband weak magnetic signal detection and DBS electrode positioning.