Catalogue Search | MBRL
Search Results Heading
Explore the vast range of titles available.
MBRLSearchResults
-
DisciplineDiscipline
-
Is Peer ReviewedIs Peer Reviewed
-
Item TypeItem Type
-
SubjectSubject
-
YearFrom:-To:
-
More FiltersMore FiltersSourceLanguage
Done
Filters
Reset
5
result(s) for
"et, Amanda Sharon"
Sort by:
Reflections on Pleasure: The Fourteenth-Century Alhambra
2009
The Nasrids were the last Islamic power on the Iberian Peninsula. They created a place of luxury and wealth in their hilltop fortress, the Alhambra, which is one of the best-preserved examples of medieval Islamic palace architecture. It was transformed in the thirteenth century into a palace-city and during most of its early history housed the most important figure in an Islamic society, the sultan. The Alhambra displays bare, natural elements on the exterior, while the interior mimics and references these natural elements in a grander fashion with gardens, fountains, beautiful vistas, sculpted porticos and lavish rooms. These interior spaces were settings for the sultan to display his wealth and power. In this thesis, I explore a selection of sites in the Alhambra by examining how decoration, courtyard gardens, water, and patronage reflect medieval Islamic notions of pleasure.Following the introduction, each chapter is focused on a specific place within the Alhambra: the Palace of the Lions, the Comares Palace, and the Royal Bath. All have survived relatively intact and date primarily to the fourteenth century. In order to best discuss pleasure, each chapter includes a discussion of building layout, decoration, gardens and the role of water, and patronage. Each section is discussed in relation to pleasure and will investigate the means by which the spaces provide pleasure.
Dissertation
Safety and efficacy of co-careldopa as an add-on therapy to occupational and physical therapy in patients after stroke (DARS): a randomised, double-blind, placebo-controlled trial
2019
Dopamine is a key modulator of striatal function and learning and might improve motor recovery after stroke. Previous small trials of dopamine agonists after stroke provide equivocal evidence of effectiveness on improving motor recovery. We aimed to assess the safety and efficacy of co-careldopa plus routine occupational and physical therapy during early rehabilitation after stroke.
This double-blind, multicentre, randomised controlled trial of co-careldopa versus placebo in addition to routine NHS occupational and physical therapy was done at 51 UK NHS acute inpatient stroke rehabilitation services. We recruited patients with new or recurrent clinically diagnosed ischaemic or haemorrhagic (excluding subarachnoid haemorrhage) stroke 5–42 days before randomisation, who were unable to walk 10 m or more, had a score of less than 7 points on the Rivermead Mobility Index, were expected to need rehabilitation, and were able to access rehabilitation after discharge from hospital. Participants were assigned (1:1) using stratified random blocks to receive 6 weeks of oral co-careldopa or matched placebo in addition to routine NHS physiotherapy and occupational therapy. The initial two doses of co-careldopa were 62·5 mg (50 mg of levodopa and 12·5 mg of carbidopa) and the remaining doses were 125 mg (100 mg of levodopa and 25 mg of carbidopa). Participants were required to take a single oral tablet 45–60 min before physiotherapy or occupational therapy session. The primary outcome was ability to walk independently, defined as a Rivermead Mobility Index score of 7 or more, at 8 weeks. Primary and safety analyses were done in the intention-to-treat population. The trial is registered on the ISRCTN registry, number ISRCTN99643613.
Between May 30, 2011, and March 28, 2014, of 1574 patients found eligible, 593 (mean age 68·5 years) were randomly assigned to either the co-careldopa group (n=308) or to the placebo group (n=285), on an average 18 days after stroke onset. Primary outcome data were available for all 593 patients. We found no evidence that the ability to walk independently improved with co-careldopa (125 [41%] of 308 patients) compared with placebo (127 [45%] of 285 patients; odds ratio 0·78 [95% CI 0·53–1·15]) at 8 weeks. Mortality at 12 months did not differ between the two groups (22 [7%] vs 17 [6%]). Serious adverse events were largely similar between groups. Vomiting during therapy sessions, after taking the study drug, was the most frequent adverse event and was more frequent in the co-careldopa group than the placebo group (19 [6·2%] vs 9 [3·2%]).
Co-careldopa in addition to routine occupational and physical therapy does not seem to improve walking after stroke. Further research might identify subgroups of patients with stroke who could benefit from dopaminergic therapy at different doses or times after stroke with more intensive motor therapy.
Medical Research Council.
Journal Article
Does Gender Affect the Link Between Organizational Citizenship Behavior and Performance Evaluation?
by
Mason, Chandra
,
Anton, Jennifer
,
Davidson, Amanda
in
Advisors
,
Biological and medical sciences
,
Citizenship
1999
Organizational citizenship behavior (OCB) is behavior that extends beyond that required by an organization in a formal job description. Past research shows that engaging in OCB is related to higher performance evaluations.
Journal Article