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Background: Oxidative stress resulting from increased free radicals and decreased antioxidants can be controlled by consuming natural antioxidants from safe sources such as red radish and soybean seeds and sprouts. Methods The chemical composition, antinutritional factors, total polyphenols, total flavonoids and antioxidant activity by DPPH were estimated. Two main groups contain 36 rats split into the first group (ve-) 6 rats, and the second group 30 rats which took 2 g/kg BW from Paracetamol for 7 days. Then divided into 5 groups, (ve+), (ve-), 10% red radish seeds and 10% red radish sprouts, 20% soybean seeds and 20% soybean sprouts for 6 weeks. MDA, GHS and CAT were evaluated. Results: significant differences in nutritional composition, polyphenols, flavonoids and antioxidant activity (DPPH). Sprouting was found to have significant nutritional value in both red radish and soybean sprouts. A Supplementation diet with 20% sprouted of soybean and 10% red radish sprouts demonstrated strong antioxidant activity across all macroscopic and biochemical parameters tested.

This investigation aimed to evaluate the effect of Rhubarb, Astragalus and Mixture of both on male obese rats. Thirty (30) adult male Sprague Dawley rats were divided into five groups. Group (1): Normal rats fed on basal diet as control negative (C-), Group (2): Control positive (C+) (untreated group). Group (3): Obese rats fed on basal diet and rhubarb (5%).Group (4): Obese rats fed on basal diet and astragalus (5%). Group (5): Obese rats fed on basal diet and mixture of both (5%). At the end of experiment, after 28 days of feeding, all serum samples were analyzed for biochemical parameters. Obese rats caused a significant decrease in the level of Hb, Ht, RBC, WBC, Neutrophils, Lymphocytes, Monocytes, Eosinphils and Basophils while a significant increase was recorded in TC, TG, VLDL, LDL, AI, U.A, Creatinine, Urea, GOT, GPT, ALP, Glucose and Plt. Obese rats treated with various diets, showed the improvement in all previous parameters.

النباتات الطبية | الأدوية | القواميس الموضوعية | الأغذية | المواد الصيدلانية | علم النبات الطبي | المواد العلاجية.

This investigation aimed to evaluate the effect of turmeric, curry leaves and mix diets on hepatointoxicated rats injected with CCl4. Thirty (30) adult male Sprague Dawley rats were divided into five groups. Group (1): Normal rats fed on basal diet as control negative (C-), Group (2): Control positive (C+) (untreated group). Group (3): Hepatointoxicated rats injected with CCl4 fed on basal diet and turmeric (4%).Group (4) Hepatointoxicated rats injected with CCl4 fed on basal diet and curry leaves (4%). Group (5): Hepatointoxicated rats injected with CCl4 fed mix diets (4%). At the end of experiment, after 28 days of feeding, all serum samples were analyzed for biochemical parameters. Injection with CCl4 caused significant decreases in BWG, FI, FER, TP, Alb, Glb, HDL & antioxidant enzymes with significant increases recorded also in organs weight, TC, TG, VLDL, LDL, U.A, creatinine, urea, GOT, GPT, ALP, glucose, total bilirubin, direct bilirubin (D.B) and indirect bilirubin (I.B). Rats treated with various (turmeric, curry) diets, showed the improvement in all previous parameters.

سعت الدراسة إلى التعرف على العلاج بالأغذية (الطب الوظيفي) دراسة فقهية طبية. وجاءت منهجية الدراسة في عزو الآيات القرآنية إلى المصحف، وتخريج الأحاديث من كتب السنة. وقسمت الدراسة إلى تمهيد وأربعة مباحث، تناول التمهيد تعريف العلاج بالأغذية (الطب الوظيفي)، والفرق بينه وبين الطب الحديث التقليدي، والطب البديل. واستعرض المبحث الأول أنواع أنظمة الغذاء العلاجية، وحكم أنظمة الغذاء العلاجية. وأشار الثاني إلى حكم التداوي والتي تمثلت في التداوي بالدواء المقطوع بإفادته، والتداوي بالدواء للمظنون به، والتداوي بالدواء الموهوم به. وتطرق الثالث إلى علاج أمراض العصر بالأغذية (أي بالطب الوظيفي) والتي اشتملت على العلاج وفق نظام غذائي معتمد، وتناول المكملات الغذائية، وترميم الأمعاء وتقوية الجهاز المناعي، والعلاج بالنوم، وطرق إزالة السموم. وتحدث الرابع عن علاج أمراض العصر بالطب الحديث (بالدواء الكيميائي). وأشارت نتائج البحث إلى أهم الفروق بين الطب الوظيفي وطب الدواء الكيميائي وأن الطب الدوائي يتم فيه علاج الأعراض فقط، وأما الطب الوظيفي فيعالج المرض نفسه، وتخفيف التوتر بسماع الأغاني أو الرقص عليها من الطرق غير المشروعة. كُتب هذا المستخلص من قِبل المنظومة 2022

The present study aims to investigate the effectiveness of three food processing by- products extracts including eggplant peel extract (EPP) , onion skin extract (OSE) , pomegranate peel extract (PPE) and their mixture in modulating the hyperglycemia using alloxane- induced diabetic rat model. Also, the effect of these extracts on diabetic complications including liver functions, serum lipid profile and antioxidant enzymes, the biomarkers of defense system in RBC's were also investigated. Treatment of rats with alloxan caused a significant (p≤ 0.05) increased in serum glucose level by the ratio 163.33% compared to normal control group. Phyto- extracts (EPE, OSE, PPE and their mixture, 150 mg/kg bw/day) , lead to decrease this elevation value and recorded 71.17, 53.25, 57.17 and 47.30%, respectively, compared to normal control group. The maximum hypoglycemic yield was noticed for the extracts mixture treatment when compared with the rest of tested extracts individually. Also, phyto- extracts treatments attenuate the different diabetic complications including liver functions and serum lipid profile. The same treatment improve the antioxidant defense system in RBCs through elevation the activities of antioxidant enzymes (glutathione peroxidase, superoxide dismutase and catalase). In conclusion, the present study has demonstrated multiple beneficial effects of EPP, OSE and PPE in combating diabetes and diabetes- related complications. Thus, we recommended such phyto- extracts to be included in our daily diets, drinks, food supplementation and pharmacological formulae.

The current work aims to determine the bioactive compounds and antioxidant activity of plant parts from food processing by- products (orange peel powder, OPP, eggplant peel powder, EPP, and tomato pomace powder, TPP). Data of proximate chemical composition of the selected plant parts powder indicated that the moisture content was ranged 6.55 to 7.92%, total protein ranged 2.53 to 5.42%, crude fat ranged 1.86 to 2.91, crude fiber ranged 18.86 to 21.98, ash content ranged 1.87 to 3.94, and carbohydrates content ranged 62.36 to 65.40%. The TPP was recorded the highest content of protein while the highest values of crude fat, fiber and ash were recorded for OPP, OPP, EPP and EPP respectively. Also, TPP recorded the highest WHC followed by OPP, Mix and EPP, respectively. Furthermore, bioactive compounds content of the selected plant parts indicated that the total phenolics was ranged 754.65 to 989.67 mg EGA/100 g, total carotenoids content was ranged 202.65 to 369.56 mg/100g and The OPP was recorded the highest content of total carotenoids while EPP recorded the highest values of total phenolics. The samples also recorded several very high biological activities which include antioxidant and scavenging of free radicals (ROO⁻) activities. When all selected food processing by- products were taken in the statistical analysis, there was a positive and highly significant (r² = 0.799 to 0.8631, p <0.05) relationship between total phenolics content and antioxidant activities. Also, the same behavior was recorded for the total carotenoids and AA. Such important biological effects could play important roles in strategies to combat/treat many diseases including obesity which oxidative stress is one of the mechanisms for its occurrence. Therefore, the present study recommended like of such plant parts powder to be included in our daily diets, drinks, food supplementation and pharmacological formulae.

Obesity increases the risk of several debilitating, and deadly diseases, including diabetes, heart disease, and some cancers. Pharmacological therapy of obesity is costly and associated with multiple side effects led to patient non- compliance. In this study, an alternative natural remedy through the use of three vegetable parts by- products of food processing (orange peel, eggplant peel, and tomato pomace) was applied in a dietary intervention to improve the complications of obesity in rats. Rats (n=36 rats) were divided into two main groups, the first group (Group 1, 6 rats) still fed on basal diet as a normal and the other main group (30 rats) was feed with diet- induced obesity (DIO) for 8 weeks which classified into five sub groups as follow: group (2) , fed on diet- induced obesity (DIO) as a positive control; groups (3,4,5 and 6) , fed on DIO containing plus 7.5% OPP, EPP, TPP and Mix (OPP+ EPP + TPP by equal parts) , respectively. At the end of the experiment (8 weeks) , rats of the normal group recorded increasing on body weight rate by 75.82% from the starting point of the experiment while obese group was 116.40%. Dietary intervention with OPP, TPP, EPP and their mixture on the diet by 7.5% induced significant decreasing on body weight of the obese rats by the rate of 99.13, 98.20, 87.10 and 82.80% from the starting point, respectively. Also, dietary intervention with OPP, TPP, EPP and their mixture induced significant ameliorative effect in different complications induced by obesity including increase the plasma non- enzymes antioxidant (GSH, and GSSG) , improve the liver functions and serum lipid profile, and decrease the blood glucose level and TBARS (biological indicator of lipid oxidation). The highest ameliorative effects was recorded for the Mix followed by EPP, TPP and OPP, respectively. In conclusion, the present data support the benefits of dietary modification, including bioactive compounds supplementation, in alleviating some complications associated obesity.