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The sorrow of war : a novel of North Vietnam
The Vietnam War as seen through the eyes of a North Vietnamese infantryman. In a series of flashbacks, as he buries the dead following a battle, the narrator recounts his 10 years of service, the comrades he lost and the way the war ruined the love of his life. The author is a veteran of the NVA's Glorious 27th Youth Brigade, a 500-man unit from which only 10 men survived. He lives in Hanoi.
Book
Lassa fever — the road ahead
Lassa virus (LASV) is endemic in the rodent populations of Sierra Leone, Nigeria and other countries in West Africa. Spillover to humans occurs frequently and results in Lassa fever, a viral haemorrhagic fever (VHF) associated with a high case fatality rate. Despite advances, fundamental gaps in knowledge of the immunology, epidemiology, ecology and pathogenesis of Lassa fever persist. More frequent outbreaks, the potential for further geographic expansion of Mastomys natalensis and other rodent reservoirs, the ease of procurement and possible use and weaponization of LASV, the frequent importation of LASV to North America and Europe, and the emergence of novel LASV strains in densely populated West Africa have driven new initiatives to develop countermeasures for LASV. Although promising candidates are being evaluated, as yet there are no approved vaccines or therapeutics for human use. This Review discusses the virology of LASV, the clinical course of Lassa fever and the progress towards developing medical countermeasures.Lassa fever is a viral haemorrhagic fever that spills over from its rodent reservoir. Continued viral evolution and increasing exposure make Lassa virus a high-risk pathogen. In this Review, Garry highlights new insights into the virology, disease presentation and potential countermeasures.
Journal Article
What caused the Vietnam War?
Examines the causes behind the Vietnam War and how different countries, including the United States, were involved.
Book
Ovulation: Parallels With Inflammatory Processes
Abstract
The midcycle surge of LH sets in motion interconnected networks of signaling cascades to bring about rupture of the follicle and release of the oocyte during ovulation. Many mediators of these LH-induced signaling cascades are associated with inflammation, leading to the postulate that ovulation is similar to an inflammatory response. First responders to the LH surge are granulosa and theca cells, which produce steroids, prostaglandins, chemokines, and cytokines, which are also mediators of inflammatory processes. These mediators, in turn, activate both nonimmune ovarian cells as well as resident immune cells within the ovary; additional immune cells are also attracted to the ovary. Collectively, these cells regulate proteolytic pathways to reorganize the follicular stroma, disrupt the granulosa cell basal lamina, and facilitate invasion of vascular endothelial cells. LH-induced mediators initiate cumulus expansion and cumulus oocyte complex detachment, whereas the follicular apex undergoes extensive extracellular matrix remodeling and a loss of the surface epithelium. The remainder of the follicle undergoes rapid angiogenesis and functional differentiation of granulosa and theca cells. Ultimately, these functional and structural changes culminate in follicular rupture and oocyte release. Throughout the ovulatory process, the importance of inflammatory responses is highlighted by the commonalities and similarities between many of these events associated with ovulation and inflammation. However, ovulation includes processes that are distinct from inflammation, such as regulation of steroid action, oocyte maturation, and the eventual release of the oocyte. This review focuses on the commonalities between inflammatory responses and the process of ovulation.
Journal Article
The land at the end of the world : a novel
A Portuguese medic, returning to Lisbon after a tour of duty in Angola, is haunted by the memories of war and feels completely detached from the ordered world of his privileged youth.
Book
Looking back on the Vietnam War : twenty-first century perspectives
\"Looking Back on the Vietnam War reflects on the half-century since the 1965 U.S. escalation of conflict in Viet Nam, asking what, how, and why we know about the Vietnam War. While the war in all of its complexities is written about from a number of disciplinary perspectives, those dominant narratives often tell a limited story, one often told in isolation from other disciplinary perspectives. Looking Back suggests we take stock of the stories absent from dominant narratives of the War, and that we do that stock-taking through the lenses of multiple disciplines and perspectives. Based on the idea that Vietnamese stories, both those set in the postwar Viet Nam and also in the Vietnamese diaspora, are crucial to understanding the Vietnam War, this volume brings together essays examining Vietnamese and diasporic conditions with those examining U.S. traces of the War. Looking Back also attends to the significance of the present in the act of recollecting as it reflects on the war's echoes in the current era of endless U.S. warring. The volume engages in a dual looking back--both in the sense of remembering and of reconsidering--to offer a fuller picture of the Vietnam War by showing the perspectives of groups and issues that have largely escaped serious attention in popular narratives of the war\"-- Provided by publisher.
Book