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Abha Guggulu (AG) is a traditional Ayurvedic herbal formulation used for treating joint disorders and bone fractures. Individually, the ingredients are known for their promising anti-inflammatory and rejuvenating actions. The present study attempts to explore the anti–arthritic potential of AG through an exploratory clinical trial.The study was conducted using a quasi-experimental model. The clinical trial has been registered in Clinical Trials Registry of India (registration number: CTRI/2019/09/021354). Osteoarthritis patients of both genders (n=12, 40–70 years age group), meeting the inclusion/exclusion criteria, were recruited in the single arm study. AG was administered in tablet form in a dose of 1.5 g, twice daily. The WOMAC score was used as a primary outcome measure. The WOMAC scale of patients was recorded on 0th, 15th and 30th days of treatment.At the end of treatment, there was a significant difference in the scores of the outcome measure. As per WOMAC total score, participants were significantly improved (p=0.002) after consuming the drug for 1 month.Overall, the data indicates significant improvement of subjects in both scales and objective measures used for assessment purposes. There were no adverse drug reactions reported during the trial. AG may be used as a safe and effective supplement to reduce symptoms of osteoarthritis. The clinical efficacy of the formulation might be mediated through the synergistic blend of herbal bioactive compounds from AG.

Background: The genus Trichoderma is widely spread in the environment, mainly in soils. Trichoderma are filamentous fungi and are used in a wide range of fields to manage plant patho-genic fungi. They have proven to be effective biocontrol agents due to their high reproducibility, adaptability, efficient nutrient mobilization, ability to colonize the rhizosphere, significant inhibitory effects against phytopathogenic fungi, and efficacy in promoting plant growth. In the present study, the antagonist Trichoderma isolates were characterized from the soil of Abha region, Saudi Arabia. Methodology: Soil samples were collected from six locations of Abha, Saudi Arabia to isolate Trichoderma having the antagonistic potential against plant pathogenic fungi. The soil dilution plate method was used to isolate Trichoderma (Trichoderma Specific Medium (TSM)). Isolated Trichoderma were evaluated for their antagonistic potential against Fusarium oxysporum, Alternaria alternata and Helminthosporium rostratum. The antagonist activity was assessed by dual culture assay, and the effect of volatile metabolites and culture filtrate of Trichoderma. In addition, the effect of different temperature and salt concentrations on the growth of Trichoderma isolates were also evaluated. Results: The most potent Trichoderma species were identified by using ITS4 and ITS 5 primers. Total 48 Trichoderma isolates were isolated on (TSM) from the soil samples out of those six isolates were found to have antagonist potential against the tested plant pathogenic fungi. In general, Trichoderma strains A (1) 2.1 T, A (3) 3.1 T and A (6) 2.2 T were found to be highly effective in reducing the growth of tested plant pathogenic fungi. Trichoderma A (1) 2.1 T was highly effective against F. oxysporum (82%), whereas Trichoderma A (6) 2.2 T prevented the maximal growth of H. rostratum (77%) according to the dual culture data. Furthermore, Trichoderma A (1) 2.1 T volatile metabolites hindered F. oxysporum growth. The volatile metabolite of Trichoderma A (6) 2.2 T, on the other hand, had the strongest activity against A. alternata (45%). The Trichoderma A (1) 2.1 T culture filtrate was proven to be effective in suppressing the growth of H. rostratum (47%). The temperature range of 26 °C to 30 °C was observed to be optimum for Trichoderma growth. Trichoderma isolates grew well at salt concentrations (NaCl) of 2%, and with the increasing salt concentration the growth of isolates decreased. The molecular analysis of potent fungi by ITS4 and ITS5 primers confirmed that the Trichoderma isolates A (1) 2.1 T, A (3) 3.1 and A (6) 2.2 T were T. harzianum, T. brevicompactum, and T. velutinum, respectively. Conclusions: The study concludes that the soil of the Abha region contains a large population of diverse fungi including Trichoderma, which can be explored further to be used as biocontrol agents.

Fungi in the genus Trichoderma are widespread in the environment, mainly in soils. They are used in agriculture because of their mycoparasitic potential; Trichoderma have the ability to increase plant health and provide protection against phytopathogens, making them desirable plant symbionts. We isolated, identified, and characterized Trichoderma from different regions of Saudi Arabia and evaluated the ability of Trichoderma to promote plant growth. Morphological and molecular characterization, along with phylogenetic studies, were utilized to differentiate between Trichoderma species isolated from soil samples in the Abha and Riyadh regions, Saudi Arabia. Then, plant growth-promoting traits of the isolated Trichoderma species were assessed. Eight Trichoderma isolates were characterized via morphological and molecular analysis; six ( Trichoderma koningiopsis , Trichoderma lixii , Trichoderma koningii , Trichoderma harzianum , Trichoderma brevicompactum , and Trichoderma velutinum ) were from Abha and two ( T. lixii and T. harzianum ) were from Riyadh. The isolated Trichoderma strains belonged to three different clades (Clade 1: Harzianum, Clade 2: Brevicompactum, and Clade 3: Viride). The Trichoderma isolates varied in plant growth-promoting traits. Seeds treated with most isolates exhibited a high percentage of germination, except seeds treated with the T3- T. koningii isolate. 100% germination was reported for seeds treated with the T4- T. harzianum and T6- T. brevicompactum isolates, while seeds treated with the T1- T. koniniopsis and T5- T. lixii isolates showed 91.1% and 90.9% germination, respectively. Seeds treated with the T8- T. velutinum , T2- T. lixii , and T7- T. harzianum isolates had germination rates of 84.1%, 82.2%, and 72.7%, respectively. The Trichoderma isolate T5- T. lixii stimulated tomato plant growth the most, followed by T7- T. harzianum , T8- T. velutinum , T4- T. harzianum , T1- T. koniniopsis , T2- T. lixii , and T6- T. brevicompactum ; the least effective was T3- T. koningii . A maximum fresh weight of 669.33 mg was observed for the T5- T. lixii -treated plants. The Abha region had a higher diversity of Trichoderma species than the Riyadh region, and most isolated Trichoderma spp. promoted tomato growth.

Land surface temperature (LST) can fully reflect the water–heat exchange cycle of the earth surface that is important for the study of environmental change. There is little research on LST in the semi-arid region of Abha-Khamis-Mushyet, which has a complex topography. The study used LST data, retrieved from ASTER data in semi-arid mountain areas and discussed its relationship with land use/land cover (LULC), topography and the normalized difference vegetation index (NDVI). The results showed that the LST was significantly influenced by altitude and corresponding LULC type. In the study area, during the summer season, extreme high-temperature zones were observed, possibly due to dense concrete surfaces. LST among different types of land use differed significantly, being the highest in exposed rocky areas and built-up land, and the lowest in dense vegetation. NDVI and LST spatial distributions showed opposite trends. The LST–NDVI feature space showed a unique ABC obtuse-angled triangle shape and showed an overall negative linear correlation. In brief, the LST could be retrieved well by the emissivity derived NDVI TES method, which relied on upwelling, downwelling, and transmittance. In addition, the LST of the semi-arid mountain areas was influenced by elevation, slope zenith angle, aspect and LULC, among which vegetation and elevation played a key role in the overall LST. This research provides a roadmap for land-use planning and environmental conservation in mountainous urban areas.

The site selection process for a building entails evaluating a variety of factors with varying degrees of importance or percentage influence. In order to ensure that critical site selection factors are not overlooked, a methodology for calculating a building’s safe site selection must be developed. The study identified three broad aspects widely considered in site selection, namely environmental, physical, and socioeconomic criteria. To assess the safest site selection of residential building construction for sustainable urban growth, we used GIS-based multi-criteria decision-making approach that combined Fuzzy-AHP and weighted linear combination (WLC) aggregation method used to calculate the SSPZ. The final safe site suitability map was generated by aggregating all aspects such as geophysical, socio-economic and Geo-environmental thematic layers and their associated Fuzzy-AHP weights using the weighted linear combination method. The sites potential index’s mean value of 0.513 with standard deviation of 0.340, minimum and maximum GeoPhySSSI are 0.0 and 0.91, respectively, SSS index is classified into zones by histogram profile using natural breaks (jenks)” Subsequently, safe sites identified and divided into six classes namely no construction, very low suitable site low suitable site, moderate suitable site, high suitable site, and very high suitable site.“ According to the statistical analysis, 3.64% and 32.12% of the total area were under very high and high SSSZ, while 26.40% and 6.22% accounted to the moderate and low suitable potential, respectively” Our findings suggest that integrating the fuzzy collection with AHP is highly desirable in terms of alternative and decision-making effectiveness. The study reveals that the areas of high and moderate suitability are located near existing habitant area, major roads, and educational and health services; they are not located in restricted/protected areas or are vulnerable to natural hazards. The findings indicate that unsuitable and less-suitable land uses such as vegetation, protected areas, and agriculture lands cover nearly one-third area of Abha-Khamis Mushyet regions, implying that using Fuzzy-AHP and GIS techniques will significantly aid in the conservation of the environment. This would significantly mitigate adverse effects on the ecosystem and climate.

Rapid changes in land use and land cover (LULC) have ecological and environmental effects in metropolitan areas. Since the 1990s, Saudi Arabia’s cities have undergone tremendous urban growth, causing urban heat islands, groundwater depletion, air pollution, loss of ecosystem services, etc. This study evaluates the variance and heterogeneity in land surface temperature (LST) because of LULC changes in Abha-Khamis Mushyet, Saudi Arabia, from 1990 to 2020. The research aims to determine the impact of urban biophysical parameters on the High–High (H–H) LST cluster using geospatial, statistical, and machine learning techniques. The support vector machine (SVM) was used to map LULC. The land surface temperature (LST) has been derived using the mono-window algorithm (MWA). The local indicator of spatial associations (LISA) model was implemented on the spatiotemporal LST maps to identify LST clusters. Also, the parallel coordinate plot (PCP) approach was employed to examine the relationship between LST clusters and urban biophysical variables as a proxy of LULC. LULC maps show that urban areas rose by > 330% between 1990 and 2020. Built-up areas had an 83.6% transitional probability between 1990 and 2020. In addition, vegetation and agricultural land have been transformed into built-up areas by 17.9% and 21.8% respectively between 1990 and 2020. Uneven LULC changes in terms of built-up areas lead to increased LST hotspots. High normalized difference built-up index (NDBI) was linked to LST hotspots but not normalized difference water index (NDWI) or normalized difference vegetation index (NDVI). This research could help policymakers develop mitigation strategies for urban heat islands.

Background Overall, stoma-related morbidity affects a reported 20–38% of pediatric patients. However, determining the true incidence of major stoma-related morbidity is challenging due to limited cohort sizes in existing studies. Thus, the aim of this study was to investigate colostomy related morbidity among children both after stoma formation and stoma closure. Methodology This is a retrospective cohort hospital-based study, conducted in an Abha maternity and children hospital, between August 1, 2018, and August 1, 2023, among 126 pediatric patients (aged 0–12 years) who underwent colostomy formation and subsequent closure during the study period. Data were collected from medical records. Data was analyzed using Statistical Package for Social Sciences (SPSS) v.26. Results This study included a total of 126 children who underwent colostomy. ( N  = 37, 29.4%) of cases included in this study were emergency cases, while ( N  = 89, 70.6%) were elective. A variety of antibiotics were used for surgical prophylaxis, metronidazole (77%) and cefuroxime (62.7%) were the most prevalent. Oral feeding was started after 5–6 days in more than one third of cases (39.7%). Wound infection ( N  = 15, 11.9%) was the most reported post-operative complication, followed with bowel obstruction ( N  = 6, 4.8%). Emergency cases had a longer duration of hospital stay than elective cases; this difference was statistically significant ( P  = .04). Conclusions Majority of patients reported no stoma related complications, while among those who reported complications, wound infection was the most reported complication, followed by bowel obstruction.

Medical students are the category of academic population with the highest levels of stress. This study aimed to assess the prevalence of academic stress among medical students in Saudi Arabia and to identify its associated factors. This cross-sectional study was conducted at the College of Medicine at King Khalid University, Abha. The Medical Student Stressor Questionnaire (MSSQ) was used to evaluate the stress caused by different factors. A total of 422 medical students participated in this study. Among the participants, 115 (27.3%) were male and 307 (72.7%) were female. The highest percentage of students were perceiving moderate to severe stress due to academic-related stressors (97.1%), followed by teaching- and learning-related stressors (93.9%) and group activities-related stressors (88.3%). The lowest domain in which students perceived moderate to severe stress was drive and desire-related stressors (65.8%). The mean percentage of students who perceived moderate-to-severe stress in all domains of stressors was 85.5%. We can conclude that medical students have a high degree of stress, and we emphasize the importance of implementing stress management programs to teach students how to handle stress in order to avoid negative effects on their health and academic performance.

PurposeThis study aims to examine the language choices of outdoor signs and menus in addition to the functions of outdoor signs in restaurants in a Saudi tourist city, Abha. The primary focus is on identifying the extent to which outdoor signs accurately represent the language choices of restaurant menus.Design/methodology/approachThe study developed a conceptual framework for the linguistic landscape (LL) of restaurants. It employed a quantitative approach to collect outdoor signs and menus of 75 sampled restaurants in Abha using online photos and a smartphone camera. Then it analyzed the frequency and percentage of language choices on outdoor signs and menus as well as the extent to which language choices of outdoor signs represent menus.FindingsThe findings indicate that more than half (58.66%) of the restaurants employ bilingual signage in both Arabic and English. Other languages like Spanish, French, Chinese and Turkish are sporadically used, with multilingualism observed only in isolated instances. The study also reveals that bi/multilingualism on outdoor signs primarily serves informational purposes, where more than one-third (36%) of the outdoor signs use languages other than Arabic to serve a symbolic function. Regarding menus, Arabic and English dominate, while Turkish appears on one menu. Spanish, French, and Chinese are absent from restaurant menus, indicating linguistic mismatch in terms of language choices.Originality/valueThis study contributes to LL studies of restaurants in tourist cities by showing language choices and functions of outdoor signs and their alignment with menus.

Background: Continuing medical education (CME) is an everlasting process throughout the physician’s working life. It helps to deliver better services for the patients. Objectives: To explore CME among resident physicians in Abha City; their current practices, their opinions, and barriers faced. Methods: A cross-sectional study was conducted among resident physicians at the Ministry of Health hospitals in Abha City using a validated self-administered questionnaire. It included personal characteristics, current CME practices, satisfaction with CME, and barriers to attendance. Results: The present study included 300 residents from 15 training specialties. Their reported CME activities during the previous year were lectures and seminars (79.7%) followed by conferences (43.7%), case presentations (39.7%), workshops (34.0%), group discussion (29/7%), and journal clubs (27.3%). Astonishingly enough, very few (8%) attended online electronic CME activities. There were significant differences in CME satisfaction scores by different training specialties. Regarding residents’ perceptions of the effectiveness of different CME activities (conferences/symposia, workshops/courses, and interdepartmental activities) the results showed that workshops and courses were significantly the most effective method compared to the other two methods in retention of knowledge, improving attitudes, improving clinical skills, improving managerial skills, and in improving practice behaviors. Barriers reported were being busy, lack of interest, high cost, and lack of suitable providers. Conclusion: Based on the findings of this study, it is recommended that online learning be promoted as a CME format for trainees. There should be support of residents and clinicians through the provision of protected time for their CME activities outside their daily clinical commitments.