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Why we die : the new science of aging and the quest for immortality
\"A groundbreaking exploration of the science of why and how we age and die-from Nobel Prize-winning molecular biologist Venki Ramakrishnan\"-- Provided by publisher.
Book
The study of dying : from autonomy to transformation
\"What is it really like to die? Though our understanding about the biology of dying is complex and incomplete, greater complexity and diversity can be found in the study of what human beings encounter socially, psychologically and spiritually during the experience. Contributors from disciplines as diverse as social and behavioural studies, medicine, demography, history, philosophy, art, literature, popular culture and religion examine the process of dying through the lens of both animal and human studies. Despite common fears to the contrary, dying is not simply an awful journey of illness and decline; cultural influences, social circumstances, personal choice and the search for meaning are all crucial in shaping personal experiences. This intriguing volume will be of interest to clinicians, professionals, academics and students of death, dying and end-of-life care, and anyone curious about the human confrontation with mortality\"--p. [4] of cover.
BOOK
Enfortumab Vedotin in Previously Treated Advanced Urothelial Carcinoma
Patients who had had a relapse after receiving platinum-containing chemotherapy and a PD-1 or PD-L1 immune checkpoint inhibitor were assigned to receive enfortumab vedotin or one of three chemotherapy agents chosen by their doctor. Enfortumab vedotin prolonged progression-free and overall survival.
Journal Article
Death : from dust to destiny
\"The terms 'birth' and 'death' have long denoted the apparent boundaries of our biological lives, situating in time the moments of coming to be and passing away. Yet the specific trajectory of a life can surpass its temporal boundaries. Long after the perishing of the body, and of its physical remains, the individual's ethos can endure in the collective memories of survivors and subsequent generations. Such remnants have been created by rituals, reinforced through commemorations and obituaries, and projected through art and architecture. These powerful inducements to remember counter the finality of physical death, bridging the gap between absence and presence. Death: From Dust to Destiny, featuring a wide-ranging collection of texts and images together with the author's guiding commentary, offers a reflective meditation on the methods that artists, architects and writers have developed to activate memory, and animate their subjects into a - possibly - unending afterlife. In this process death need no longer be a terminal departure but can become a new form of existence in the minds of others.\"--Jacket flap.
Book
Sudden cardiac death—update
Sudden cardiac death (SCD) is one of the most common causes of death worldwide with a higher frequency especially in the young. Therefore, SCD is represented frequently in forensic autopsy practice, whereupon pathological findings in the heart can explain acute death. These pathological changes may not only include myocardial infarction, coronary thrombosis, or all forms of myocarditis/endocarditis but also rare diseases such as hereditary structural or arrythmogenic anomalies, lesions of the cardiac conduction system, or primary cardiac tumours.
Journal Article
Persons, humanity, and the definition of death
In this riveting and timely work, John P. Lizza presents the first comprehensive analysis of personhood and humanity in the context of defining death. Rejecting the common assumption that human or personal death is simply a biological phenomenon for biologists or physicians to define, Lizza argues that the definition of death is also a matter for metaphysical reflection, moral choice, and cultural acceptance.
Lizza maintains that defining death remains problematic because basic ontological, ethical, and cultural issues have never been adequately addressed. Advances in life-sustaining technology and organ transplantation have led to revision of the legal definition of death. It is generally accepted that death occurs when all functions of the brain have ceased. However, legal and clinical cases involving postmortem pregnancy, individuals in permanent vegetative state, those with anencephaly, and those with severe dementia challenge the neurological criteria. Is \"brain death\" really death? Should the neurological criteria be expanded to include individuals in permanent vegetative state, with anencephaly, and those with severe dementia? What metaphysical, ethical, and cultural considerations are relevant to answering such questions?
Although Lizza accepts a pluralistic approach to the legal definition of death, he proposes a nonreductive, substantive view in which persons are understood as \"constituted by\" human organisms. This view, he argues, provides the best account of human nature as biological, moral, and cultural and supports a consciousness-related formulation of death. Through an analysis of legal and clinical cases and a discussion of alternative concepts of personhood, Lizza casts greater light on the underlying themes of a complex debate.
eBook