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"FTAM"
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Application of a minimally invasive full‐thickness autologous microcolumn skin harvesting device for donor site tissue collection and augmenting wound healing in a porcine wound model
by
Curtis, Brenda
,
Prevish, Brian
,
Goedegebuure, Madeleine
in
Animals
,
Disease Models, Animal
,
Fibroblasts
2024
Using a 6‐week porcine full‐thickness excisional wound grafting model, we evaluated the Autologous Regeneration of Tissue (ART®) System, a novel skin harvesting device designed to collect autologous full‐thickness autologous microcolumns (FTAM) at 0.5 mm in diameter. The donor skin sites were harvested using the ART® System and compared to split‐thickness skin grafts (STSGs). Recipient sites were divided into three treatment groups: FTAM, STSG and Untreated control. Comparing the FTAM donor sites to the STSG donor sites, we observed significantly faster re‐epithelization by Day 4 (p < 0.05), earlier adnexal structures and rete ridge formation by Week 3, and increased collagen and elastin content by Week 6. We also observed an increased rate of healing at the FTAM donor site whilst limiting donor site morbidity compared to traditional STSG donor sites. Time to recipient site closure was 2.4 weeks for STSG treated, 3.3 weeks for FTAM treated and 4.1 weeks for the Untreated control (p < 0.05). The STSG and FTAM recipient sites reached complete re‐epithelialization by Weeks 4 and 5, respectively which was significantly faster compared to the Untreated control. However, the FTAM recipient site received only 10% of the donor site tissue relative to the recipient site area and the amount of donor site tissue grafted on the STSG recipient sites was 5× more than the FTAM recipient sites. Additionally, the FTAMs harvested by the ART® System augmented recipient wound site healing as a result of ‘epithelial island’ expansion in contrast to Untreated control sites that closed primarily by contracture.
Journal Article
Semi analytical solution strategy for fractional Fornberg Whitham equation using Temimi Ansari method
2025
This study presents semi-analytical solutions for the fractional Fornberg–Whitham (FFW) equation using the Fractional Temimi–Ansari Method (FTAM). Fractional derivatives are defined in the senses of Atangana–Baleanu–Caputo (ABC) and Caputo. The existence and uniqueness of solutions are rigorously examined. Furthermore, a detailed discussion of the FTAM framework, including convergence analysis is provided. The accuracy of the obtained solutions is validated through comparisons with exact solutions when the fractional order is
. Another key objective of the study is to compare the two fractional derivative definitions to assess the extent to which each captures memory effects from the past. Owing to its Mittag-Leffler-type kernel, the ABC derivative enhances memory effects and promotes faster stabilization.
Journal Article
Performance of MAP in the remote operation of a CNC
1990
A major issue for the users of the Manufacturing Automation Protocol (MAP) is its performance in servicing time-critical applications. The author describes an experiment in which a computerized numerical controller (CNC) is remotely operated using MAP. A set of critical timing parameters is defined, a performance analysis of the system from the user's point of view is carried out, and a comparison with other similar systems is made. The transfer time between two front-end processors, implementing the seven MAP layers, for a 100-byte-long message is found to be about 18 ms, and the transfer time for the same message between two user processes on the hosts is about 40 ms.< >
Journal Article