Explore the vast range of titles available.

This study directly compared the performance of a contralateral routing of signal (CROS)/bilateral routing of signal (BiCROS) and a soft-band bone-anchored hearing aid (BAHA) in patients with unilateral sensorineural hearing loss (SNHL) and assessed the relationship between hearing aid benefits and personal factors. Participants with unilateral SNHL were prospectively enrolled in the study and were tested under the following three conditions: unaided, with CROS/BiCROS, and with soft-band BAHA. Sound localization, consonant, hearing in noise, and psychoacoustic tests were performed. Pseudobinaural benefits (e.g., squelch, summation, and head shadow effect) were obtained in both the CROS/BiCROS and soft-band BAHA conditions and compared to the unaided condition. Sound localization ability was not improved in either the CROS/BiCROS condition or soft-band BAHA condition. Rather, sound localization ability was significantly decreased in the CROS/BiCROS setting. A CROS/BiCROS hearing aid and a soft-band BAHA provided additional benefit for speech-in-noise perception when target speech was directed to the impaired ear side. The CROS/BiCROS hearing aid was superior to the soft-band BAHA one in decreasing the head shadow effect, but it appeared to have a negative effect when the noise was delivered to the better ear. The positive and negative effects of CROS/BiCROS for localization and speech perception were significantly correlated with personal factors such as age, hearing threshold in the better ear, and unaided psychoacoustic performances. Despite the lack of device acclimatization, we believe that this study provides counseling information for hearing aid clinics to use in the context of patients with unilateral SNHL.

There is currently a lack of prospective studies comparing multiple treatment options for single-sided deafness (SSD) in terms of long-term sound localization outcomes. This randomized controlled trial (RCT) aims to compare the objective and subjective sound localization abilities of SSD patients treated with a cochlear implant (CI), a bone conduction device (BCD), a contralateral routing of signals (CROS) hearing aid, or no treatment after two years of follow-up. About 120 eligible patients were randomized to cochlear implantation or to a trial period with first a BCD on a headband, then a CROS (or vice versa). After the trial periods, participants opted for a surgically implanted BCD, a CROS, or no treatment. Sound localization accuracy (in three configurations, calculated as percentage correct and root-mean squared error in degrees) and subjective spatial hearing (subscale of the Speech, Spatial and Qualities of hearing (SSQ) questionnaire) were assessed at baseline and after 24 months of follow-up. At the start of follow-up, 28 participants were implanted with a CI, 25 with a BCD, 34 chose a CROS, and 26 opted for no treatment. Participants in the CI group showed better sound localization accuracy and subjective spatial hearing compared to participants in the BCD, CROS, and no-treatment groups at 24 months. Participants in the CI and CROS groups showed improved subjective spatial hearing at 24 months compared to baseline. To conclude, CI outperformed the BCD, CROS, and no-treatment groups in terms of sound localization accuracy and subjective spatial hearing in SSD patients. TRIAL REGISTRATION Netherlands Trial Register (https://onderzoekmetmensen.nl): NL4457, CINGLE trial.

•EEG Spectral exponent noninvasively indexes cortical excitatory-inhibitory balance.•Bilateral hearing loss reduces exponent, longer duration restores it towards normal.•Left vs. right deafness show distinct lateralized patterns in spectral exponent.•Resting-state exponent predicts speech-in-noise tracking across hearing disorders. Excitation–inhibition balance is a fundamental property of cortical circuits, reflecting homeostatic plasticity that stabilizes neural activity in the face of functional disruption. This framework has been widely implicated in sensory deprivation and psychiatric disorders. In the auditory domain, it remains unclear how long-term bilateral and unilateral hearing loss reorganizes cortical E-I balance and how such reorganization affects speech processing. Here, we recorded resting-state EEG and measured spectral exponents as a noninvasive proxy for cortical E-I balance in individuals with bilateral hearing loss, single-sided deafness, and normal hearing. We found that spectral exponents differed systematically across hearing loss types. Participants with bilateral hearing loss exhibited reduced exponents, primarily in central-parietal regions, relative to normal-hearing controls, with a gradual increase with prolonged hearing-loss duration. In contrast, left- and right-sided deafness showed distinct patterns of hemispheric lateralization in spectral exponents. Participants also performed a naturalistic speech listening task, allowing quantification of neural tracking of speech. It showed stronger envelope tracking response for bilateral hearing loss group than normal control. Importantly, resting-state exponents across all hearing-impaired groups robustly predicted the strength of speech envelope tracking in noisy environments. These findings reveal dissociable patterns of aperiodic cortical dynamics following bilateral and unilateral auditory deprivation and highlight the homeostatic plasticity in supporting speech perception under challenging listening conditions.

Sound localization is essential for auditory spatial awareness. The process relies on interaural differences in timing and level, and spectral cues. This study aimed to standardize sound-localization testing conditions across facilities in Japan, analyze the impact of early reflected sounds on localization accuracy, and compare outcomes between individuals with normal hearing and those with unilateral hearing loss. This study included 77 participants with normal hearing and 45 individuals with unilateral hearing loss, at 11 facilities. Sound-localization tests were conducted using nine loudspeakers arranged in a 180° horizontal arc. The stimuli consisted of Comité Consultatif International Téléphonique et Télégraphique (CCITT) and low-pass CCITT noise bursts at randomized levels of 50, 55, and 60 dB SPL. The reflected sound measurements employed time-stretched pulses to analyze early reflections (4–7 ms). The localization accuracy was assessed using the root-mean-square error and mean deviation score. Localization performance was negatively influenced by early reflections, with reflected sound envelope area and peak values within 4–7 ms correlating significantly with reduced accuracy (r = −0.535 to −0.555). Participants with normal hearing achieved a root-mean-square error of 2.0° ± 4.8°, whereas participants with unilateral hearing loss exhibited significantly greater errors (68.4° ± 40.7°, p < .001). Asymmetries in the left–right response accuracy correlated positively with the reflected sound characteristics (r > 0.6). Noise type (normal vs. low-pass CCITT) did not significantly impact performance in either group. Early reflections significantly compromise sound-localization accuracy, particularly in smaller testing environments where reflections overlap with direct sounds. Standardized testing protocols, in which early reflections are controlled, are critical for reliable assessments. The use of sound-absorbing materials can enhance the test precision, particularly in the clinical evaluation of unilateral hearing loss. These findings emphasize the need for optimizing acoustic conditions to improve the reliability and accuracy of sound-localization testing.

Purpose Listening-related fatigue is an understudied construct that may contribute to the auditory, educational, and psychosocial problems experienced by children with unilateral hearing loss (UHL). Herein, we present an overview of listening-related fatigue in school-age children with hearing loss (CHL), with a focus on children with UHL. Method Following a review of research examining listening-related fatigue in adults and CHL, we present preliminary findings exploring the effects of unilateral and bilateral hearing loss on listening-related fatigue in children. For these exploratory analyses, we used data collected from our ongoing work developing and validating a tool, the Vanderbilt Fatigue Scale, for measuring listening-related fatigue in children. Presently, we are assessing 3 versions of the fatigue scale-child self-report, parent proxy, and teacher proxy. Using these scales, data have been collected from more than 900 participants. Data from children with unilateral and bilateral hearing loss and for children with no hearing loss are compared with adult Vanderbilt Fatigue Scale data. Results Results of our literature review and exploratory analyses suggest that adults and CHL are at increased risk for listening-related fatigue. Importantly, this increased risk was similar in magnitude regardless of whether the loss was unilateral or bilateral. Subjective ratings, based on child self-report and parent proxy report, were consistent, suggesting that children with unilateral and bilateral hearing loss experienced greater listening-related fatigue than children with no hearing loss. In contrast, results based on teacher proxy report were not sensitive to the effects of hearing loss. Conclusions Children with UHL are at increased risk for listening-related fatigue, and the magnitude of fatigue is similar to that experienced by children with bilateral hearing loss. Problems of listening-related fatigue in school-age CHL may be better identified by CHL themselves and their parents than by teachers and specialists working with the children.

An essential task for the central auditory pathways is to parse the auditory messages sent by the two cochleae into auditory objects, the segregation and localisation of which constitute an important means of separating target signals from noise and competing sources. When hearing losses are too asymmetric, the patients face a situation in which the monaural exploitation of sound messages significantly lessens their performance compared to what it should be in a binaural situation. Rehabilitation procedures must aim at restoring as many binaural advantages as possible. These advantages encompass binaural redundancy, head shadow effect and binaural release from masking, the principles and requirements of which make up the topic of this short review. Notwithstanding the complete understanding of their neuronal mechanisms, empirical data show that binaural advantages can be restored even in situations in which faultless symmetry is inaccessible.

Purpose Single-sided deafness (SSD) presents significant challenges for patients, including compromised sound localization, reduced speech recognition, and often, tinnitus. These issues are typically addressed using interventions such as cochlear implantation (CI) and bone conduction implant (BCI). However, evidence regarding the efficacy of BCI in reducing tinnitus in SSD patients remains limited. This study explored the ability of a novel active transcutaneous BCI (Bonebridge BCI602) to alleviate tinnitus in SSD patients. Study design Prospective cohort multicenter study. Setting Tertiary referral hospitals. Methods A prospective multicenter study of 30 SSD patients was conducted. The patients were divided into two groups: those with ( n  = 19) and without ( n  = 11) tinnitus. Audiometric assessments, subjective questionnaires including the Abbreviated Profile of Hearing Aid Benefit (APHAB) and the Bern Benefit in Single-Sided Deafness (BBSS), and tinnitus evaluations with the Tinnitus Handicap Inventory (THI) and tinnitogram were conducted before and after BCI surgery. Results THI scores after surgery were significantly reduced in SSD patients with tinnitus. Subjective satisfaction improved in both the tinnitus and non-tinnitus groups; however, the former group exhibited a significantly greater improvement in the APHAB questionnaire score. According to tinnitograms, the loudness of tinnitus decreased, particularly in patients with ipsilateral tinnitus. Patients with residual hearing had greater reductions in their THI scores. However, three patients without residual hearing had a relative worsening of tinnitus after surgery. Conclusion The Bonebridge BCI602 effectively reduced tinnitus in SSD patients, particularly in those with residual hearing. Subjective satisfaction improved in both the tinnitus and non-tinnitus groups. These findings demonstrate the therapeutic potential of BCI for managing SSD and associated tinnitus.

Background: Bilateral sudden sensorineural hearing loss (BSSHL) is rare and assumed to be a different clinical entity compared to unilateral SSHL (USSHL). This study examined the differences between the idiopathic BSSHL and USSHL. Methods: Forty-six sequential BSSHL patients (Se-BSSHL) and 68 simultaneous BSSHL (Si-BSSHL) were consecutively admitted between June 2008 and December 2015. Two sets of patients served as control groups: (1) USSHL patients with healthy contralateral ear and (2) USSHL patients with contralateral preexisting hearing loss (USSHLwCHL). We retrospectively analyzed differences among four cohorts using analysis of variance, Kruskal-Wallis test, Welch's t-test, and Chi-square test as appropriate before and after propensity score matching (PSM) based on age, gender, and body mass index (BMI). Results: The prevalence of idiopathic BSSHL was 8.6% (114/1329) among the total SSHL patients. In the total cohort, USSHL patients tended to be younger, female, and tended to have lower BMI, renal parameters, and total cholesterol in addition to higher high-density lipoprotein compared to the other three groups. Most routine blood indicators, some coagulation markers, and immunoglobulin M (H = 13.4, P = 0.004) were significantly different among the study groups. After PSM, the major significant differences were found in audiometric characteristics. Si-BSSHL and Se-BSSHL patients demonstrated similar hearing thresholds as USSHL but were significantly better than the USSHLwCHL patients across most frequencies before and after treatment (H = 30.0, P < 0.001 for initial hearing and H = 12.0, P = 0.007 for final hearing). Moreover, the BSSHL patients showed different hearing loss distribution patterns (more descending type, χ2 = 33.8, P = 0.001) with less hearing gain (H = 17.5, P < 0.001) compared to the USSHL patients. Conclusions: Idiopathic BSSHL is a relatively rare subtype of SSHL with a higher rate of descending audiogram type and inferior hearing outcome rather than being classified as a completely different disease entity compared to USSHL.

The study aimed to improve outcomes in Nucleus cochlear implant (CI) recipients with single-sided deafness (SSD) by reducing interaural frequency and loudness mismatches through device programming. In Experiment 1a, a modified frequency allocation table (FAT) was created to better match the tonotopicity of the contralateral ear and reduce interaural frequency mismatch. Twenty experienced SSD-CI users completed localization and speech recognition tests with their everyday FAT. Tests were repeated after 6 weeks’ use of the modified FAT. Participants compared both FATs for 2 weeks before being tested again with each. For 10 newly implanted SSD-CI recipients (Experiment 1b), Group A was programmed with the manufacturer's default FAT and Group B with the modified FAT at activation. Speech recognition and localization were completed, after 6 weeks’ use of each FAT. Participants then compared both FATs before testing with each. In Experiment 2, 15 experienced SSD-CI users were evaluated with their everyday program and a modified loudness program, which was created to obtain audibility of ∼20 dB HL from 0.25 to 6 kHz and balanced loudness between ears. Three test sessions occurred, resembling Experiment 1a. Experienced participants in Experiments 1a and 2 showed significant improvement in one speech-in-noise task with a modified program compared to the everyday program. Newly implanted recipients showed no significant difference in results between FATs. Results indicate that modified programs, created to reduce interaural mismatches, may improve outcomes. The first month after activation might be too early to compare FATs as SSD-CI recipients are adjusting to electric hearing.

Cochlear implantation for single-sided deafness (SSD) is the only treatment option with the potential to restore binaural hearing cues. Significant binaural benefit has been measured in adults by speech in noise and localisation tests, who receive a cochlear implant for SSD, however, little is known on the cortical changes that help provide this benefit. In the present study, detection of sound in the auditory cortex, speech testing and localisation was used to investigate the ability of a cochlear implant (CI) to restore auditory cortical latencies and improve binaural benefit in the adult SSD population. Twenty-nine adults with acquired single-sided deafness who received a CI in adulthood were studied. Speech perception in noise was tested using the Bamford-Kowal-Bench speech-in-noise test, localisation ability was measured using the auditory speech sounds evaluation (AδE) localisation test and cortical auditory evoked responses, comparing N1-P2 latencies recorded from the normal hearing ear and cochlear implant were used to investigate the synchrony of the cortical pathway from the CI and normal hearing ear (NHe) with binaural hearing function. There was a significant improvement in speech perception in noise in all spatial configurations S0/N0 (Z = -3.066, p<0.002), S0/NHE (Z = -4.031, p<0.001), SCI/NHE (Z = -3.851, p<0.001). Localization significantly improved when tested with the cochlear implant on (p<0.001) with a shorter duration of deafness correlating to a greater improvement in localisation ability F(1:18) = 6.854; p = 0.017). There was no significant difference in N1-P2 latency recorded from the normal hearing ear and the CI. Cortical auditory evoked response latencies recorded from the CI and NHe showed no significant difference, indicating that the detection of sound in the auditory cortex occurred simultaneously, providing the cortex with auditory information for binaural hearing.