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In this manuscript, new quadrant-based search algorithm with zero motion prejudgment is proposed for motion estimation (ME) in HEVC (High Efficiency Video Coding) standard. The HEVC standard is used to obtain efficient output with low motion estimation time. The proposed quadrant-based search algorithm is a fast block matching algorithm that obtain better block matching amid the current block and reference block. The zero motion prejudgment (ZMP) method is used to find the block, whether it is motion or static and it is used for decreasing the computational complexity (CC) in the proposed quadrant-based search algorithm. The proposed quadrant-based search algorithm with ZMP technique for motion estimation in HEVC is implemented on the FPGA hardware platform. The entire architecture is executed in Verilog HDL with Virtex-5 technology and integrated with Xilinx ISE Design Suite 14.5. The results are integrated into the CIF (352 × 288 pixels) and HD (1280 × 720 pixels) video input sequence. The evaluation metrics like PSNR, Motion estimation time, sum of absolute difference (SAD) value are analyzed with existing method like hexagon, adaptive root pattern algorithm, and diamond search algorithm. Then the hardware parameters like power consumption and maximum operating frequency are measured. The hardware utilization is reduced and the power consumption of the proposed model is diminished to 0.143 W. The maximal operating frequency of the proposed model is 440.470 MHz. The experimental outcomes demonstrate that the proposed motion evaluation approach in HEVC is more effective than existing algorithms.

This study aimed to classify the moods of the song based on musical features that include Acousticness, danceability, energy, Instrumentalness, loudness, liveliness, valence, tempo, and Speechiness. The researcher used the circumplex plane of James Russell, which has four quadrants. Quadrant 1 (Q1) says that when arousal is higher than 5 and valence is lower than 5, the mood is happy. Quadrant 3 (Q3) says that when arousal is lower than 5 and valence is higher than 5, the mood is sad, and Quadrant 4 (Q4) says that when arousal is lower than 5 and valence is higher than 5, the mood is calm. The desktop application music player was integrated to automatically categorize the moods of the songs after testing and training. The leverage of the TensorFlow algorithm will be the basis for classification.

Ferroelectric materials have a spontaneous electric polarization that can be manipulated for applications. The polarization is usually not uniform throughout the material, and for nanosized ferroelectrics, polarization can be quite complex. Using scanning transmission electron microscopy, Tang et al. found that in thin films of the ferroelectric PbTiO3, the polarization vector rotated in space, forming a closed loop, the so-called flux closure. The flux closure structures formed an array, with the period dependent on the width of the thin film, and caused the buildup of considerable strain within the crystal lattice of the material Science, this issue p. 547 Nanoscale ferroelectrics are expected to exhibit various exotic domain configurations, such as the full flux-closure pattern that is well known in ferromagnetic materials. Here we observe not only the atomic morphology of the flux-closure quadrant but also a periodic array of flux closures in ferroelectric PbTiO3 films, mediated by tensile strain on a GdScO3 substrate. Using aberration-corrected scanning transmission electron microscopy, we directly visualize an alternating array of clockwise and counterclockwise flux closures, whose periodicity depends on the PbTiO3 film thickness. In the vicinity of the core, the strain is sufficient to rupture the lattice, with strain gradients up to 109 per meter. Engineering strain at the nanoscale may facilitate the development of nanoscale ferroelectric devices.

In order to analyze the positioning accuracy of the four-quadrant detector, this paper deeply studies the positioning principle of the four-quadrant detector, establishes the mathematical model of azimuth standard deviation based on Gaussian facula, and deeply analyzes the influence of each factor on the positioning accuracy from the three influencing factors of facula position, facula radius and signal-to-noise ratio. The results show that the positioning accuracy can be effectively improved by improving the signal-to-noise ratio, using smaller light spot and making the light spot as close to the center of the detector as possible.

Aortic dissection often initiates a few centimeters distal to the coronary ostia in the right lateral wall, with an intimal-medial tear that tends to be transversely directed and occupy half of the aortic circumference, sometimes less, but seldom the entire circumference. To elucidate these clinical observations, tear tests were presently used to determine the layer-specific resistance to tear propagation in ascending thoracic aortic aneurysms, assessing variations over the four circumferential quadrants and two directions. Aneurysmal tissue strips of standardized dimensions from sixteen patients were anatomically separated into layers (seven hundred and twelve) and an incision made along one-third of their length. They underwent tear testing via uniaxial loading and then unloading before crack propagation had proceeded along their complete length. The average tear tension and tear energy per reference area generated were many-fold greater in outer- (adventitial) compared to inner- (intimal with small medial portion) and middle-layer (medial) strips, explaining why the tear is restricted to the inner wall. They were greater in inner- compared to middle-layer strips of the anterior and left lateral quadrants, suggesting that the tear will propagate to the less-resistant media even if initiated in the intima. In most longitudinally-cut middle- and inner-layer strips, the cracks deviated toward the circumferential direction and tore out through the side, justifying the circumferential course of the tear. Both fracture parameters were significantly higher in the right than the left lateral quadrant in outer-layer strips and the anterior quadrant in middle-layer strips, potentially affecting the circumferential extent of the tear.

We consider the problem of Bitsadze–Samarskii type for a generalized Tricomi equation with a spectral parameter in the case where the equation is elliptic in the first quadrant of the plane. We establish the existence and uniqueness of a solution to the problem.

Managed retreat is a potentially important climate change adaptation option, providing an alternative to structural protection or accommodation measures to manage natural hazard risk. However, its application faces challenges given the projected scale of climate-induced displacement and the difficulties of resettlement. We evaluate the drivers, barriers and outcomes of 27 recent cases of managed retreat that have resettled approximately 1.3 million people. A conceptual model based on two key factors—who benefits from retreat and who initiates it—organizes the diverse set of cases into four quadrants. Different sociopolitical dimensions emerge as particularly influential in each quadrant. The model establishes a foundation for understanding and anticipating case-specific complexities. It can be used to unpack the landscape of managed retreat and evaluate its potential future applications. Managed retreat is a potentially important climate change adaptation option. In this article the drivers and outcomes of, and barriers to, 27 recent cases of managed retreat—involving the resettlement of approximately 1.3 million people—are evaluated.

Here, we present the results of turbulent flow structures and their influence on aeolian sand transport over gobi surfaces based on quadrant analysis. The results show that the classified turbulent structures over gobi accounted for 43%–44% of the time frequency and contributed ∼97% to the Reynolds stress, yet the contribution rates to sand transport rate ranged from 45% to 52%. Sweeps (Quadrant 4) and ejections (Q2) were the two most frequent events and accounted for 70% of the total frequency for the classified turbulent structures. Sweeps made a major contribution of 51%–57% to sand transport rate over gobi. Outward interactions (Q1) were relatively rare, but they individually entrained as much sand as sweeps of comparable magnitude and duration. The turbulent structures over gobi show similar behaviors comparable to those of water flows over gravel riverbeds or rough seabeds yet different from those of air flow over flat sand surfaces. Plain Language Summary Turbulence is the driving factor for aeolian sand transport. Turbulence behavior over gobi, a major type of rough land surface in Asia, and its influence on sand transport are poorly understood. Quadrant analysis has been widely used to evaluate boundary layer turbulence based on the streamwise (u′) and vertical (w′) fluctuating wind speed components from the mean. Four distinct quadrants can be defined, that is, outward interactions (Q1) (u′ > 0, w′ > 0), ejections (Q2) (u′ < 0, w′ > 0), inward interactions (Q3) (u′ < 0, w′ < 0), and sweeps (Q4) (u′ > 0, w′ < 0). The quadrant analysis shows that sweeps and ejections were the two most frequent turbulent structures over gobi, accounting for a total frequency of 70%. Sweeps made the largest contribution to sand transport rate over gobi. In contrast, outward interactions were individually as effective as sweeps, and they contributed less to sand transport rate than sweeps only because they were less common. The presence of gravel on the gobi surface affects the surrounding flow field and makes the turbulent structures different from those over flat sand surfaces, highlighted by the more frequent occurrence of ejections and sweeps, whereas they show similar characteristics to those over gravel riverbeds or rough seabeds. Key Points Turbulent flow structures over a gobi surface and their impact on sand transport rate were examined Sweeps made the largest contribution to sand transport rate over gobi, while outward interactions were individually as effective as sweeps The behavior of turbulent flow over gobi surfaces shows similar turbulence characteristics to water flows over rough riverbeds or seabeds

Wound infections are the main cause of sepsis in patients with burns and increase burn-related morbidity and mortality. Bacteriophages, natural bacterial viruses, are being considered as an alternative therapy to treat infections caused by multidrug-resistant bacteria. We aimed to compare the efficacy and tolerability of a cocktail of lytic anti-Pseudomonas aeruginosa bacteriophages with standard of care for patients with burns. In this randomised phase 1/2 trial, patients with a confirmed burn wound infection were recruited from nine burn centres in hospitals in France and Belgium. Patients were eligible if they were aged 18 years or older and had a burn wound clinically infected with P aeruginosa. Eligible participants were randomly assigned (1:1) by use of an interactive web response system to a cocktail of 12 natural lytic anti-P aeruginosa bacteriophages (PP1131; 1 × 106 plaque-forming units [PFU] per mL) or standard of care (1% sulfadiazine silver emulsion cream), both given as a daily topical treatment for 7 days, with 14 days of follow-up. Masking of treatment from clinicians was not possible because of the appearance of the two treatments (standard of care a thick cream, PP1131 a clear liquid applied via a dressing), but assignments were masked from microbiologists who analysed the samples and patients (treatment applied while patients were under general anaesthetic). The primary endpoint was median time to sustained reduction in bacterial burden by at least two quadrants via a four-quadrant method, assessed by use of daily swabs in all participants with a microbiologically documented infection at day 0 who were given at least one sulfadiazine silver or phage dressing (modified intention-to-treat population). Safety was assessed in all participants who received at least one dressing according to protocol. Ancillary studies were done in the per-protocol population (all PP1131 participants who completed 7 days of treatment) to assess the reasons for success or failure of phage therapy. This trial is registered with the European Clinical Trials database, number 2014-000714-65, and ClinicalTrials.gov, number NCT02116010, and is now closed. Between July 22, 2015, and Jan 2, 2017, across two recruitment periods spanning 13 months, 27 patients were recruited and randomly assigned to receive phage therapy (n=13) or standard of care (n=14). One patient in the standard of care group was not exposed to treatment, giving a safety population of 26 patients (PP1131 n=13, standard of care n=13), and one patient in the PP1131 group did not have an infection at day 0, giving an efficacy population of 25 patients (PP1131 n=12, standard of care n=13). The trial was stopped on Jan 2, 2017, because of the insufficient efficacy of PP1131. The primary endpoint was reached in a median of 144 h (95% CI 48–not reached) in the PP1131 group versus a median of 47 h (23–122) in the standard of care group (hazard ratio 0·29, 95% CI 0·10–0·79; p=0·018). In the PP1131 group, six (50%) of 12 analysable participants had a maximal bacterial burden versus two (15%) of 13 in the standard of care group. PP1131 titre decreased after manufacturing and participants were given a lower concentration of phages than expected (1 × 102 PFU/mL per daily dose). In the PP1131 group, three (23%) of 13 analysable participants had adverse events versus seven (54%) of 13 in the standard of care group. One participant in each group died after follow-up and the deaths were determined to not be related to treatment. The ancillary study showed that the bacteria isolated from patients with failed PP1131 treatment were resistant to low phage doses. At very low concentrations, PP1131 decreased bacterial burden in burn wounds at a slower pace than standard of care. Further studies using increased phage concentrations and phagograms in a larger sample of participants are warranted. European Commission: Framework Programme 7.