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"Rocks Humor."
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Mountains of jokes about rocks, minerals, and soil : laugh and learn about science
\"Learn about minerals, the Earth's layers and plates, lava and more. Read jokes about all of these topics, and learn how to write your own\"-- Provided by publisher.
BOOK
Brit wits
Through a compilation of essays and profiles, Brit Wits shows how and why humour has been such a powerful catalyst and expressive force in rockers' work. Ellis trains his attention on those whose music and persona exude defiance to investigate the nature of rock humour and how these groups have used it to attack prevailing social structures.
eBook
Ethnic Humor in Multiethnic America
When wielded by the white majority, ethnic humor can be used to ridicule and demean marginalized groups. In the hands of ethnic minorities themselves, ethnic humor can work as a site of community building and resistance. In nearly all cases, however, ethnic humor can serve as a window through which to examine the complexities of American race relations. InEthnic Humor in Multiethnic America, David Gillota explores the ways in which contemporary comic works both reflect and participate in national conversations about race and ethnicity.Gillota investigates the manner in which various humorists respond to multiculturalism and the increasing diversity of the American population. Rather than looking at one or two ethnic groups at a time-as is common scholarly practice-the book focuses on the interplay between humorists from different ethnic communities. While some comic texts project a fantasy world in which diverse ethnic characters coexist in a rarely disputed harmony, others genuinely engage with the complexities and contradictions of multiethnic America.The first chapter focuses on African American comedy with a discussion of such humorists as Paul Mooney and Chris Rock, who tend to reinforce a black/white vision of American race relations. This approach is contrasted to the comedy of Dave Chappelle, who looks beyond black and white and uses his humor to place blackness within a much wider multiethnic context.Chapter 2 concentrates primarily on the Jewish humorists Sarah Silverman, Larry David, and Sacha Baron Cohen-three artists who use their personas to explore the peculiar position of contemporary Jews who exist in a middle space between white and other.In chapter 3, Gillota discusses different humorous constructions of whiteness, from a detailed analysis ofSouth Parkto \"Blue Collar Comedy\" and the blogStuff White People Like.Chapter 4 is focused on the manner in which animated children's film and the network situation comedy often project simplified and harmonious visions of diversity. In contrast, chapter 5 considers how many recent works, such asHarold and Kumar Go to White Castleand the Showtime seriesWeeds, engage with diversity in more complex and productive ways.
eBook
The Téchne of the 21st Century Transgressive Laughter: Stiob, Holy Foolishness, Rock Counterculture and Carnivalesque Trolling
This article offers a comprehensive theorization of stiob as a historically sedimented, culturally specific, yet increasingly globalized modality of ironic discourse whose logic of deadpan overidentification has migrated from late-Soviet conceptualist counterculture into twenty-first-century political communication. Revisiting the folkloric, carnivalesque, and double-voiced foundations of stiob, this study situates the phenomenon within the longue durée of Russian humor, holy foolishness (юрoдствo), and the grotesque tradition described by Dmitry Likhachev, Aleksandr Panchenko, Mikhail Bakhtin, and Sergei Averintsev. The argument proceeds to demonstrate how contemporary political actors—most prominently Donald Trump and Vladimir Putin—have appropriated stiob and its adjacent practices (holy foolishness, trolling, strategic sacrilege, and carnivalesque inversion) as powerful rhetorical instruments capable of destabilizing discursive norms, undermining institutional authority, and creating a semi-permanent state of “infernal laughter.” Drawing on examples from political speech, social media, public performance, and mediatized spectacle, the article contends that both Trump and Putin deploy a repertoire of ironic aggression, misdirection, double-voiced innuendo, and taboo-breaking parody that weaponizes cultural archetypes of the jester, trickster, and holy fool. This mode of communication, simultaneously theatrical and destructive, produces a new form of political carnivalesque in which hierarchical orders are inverted, outrage is instrumentalized, and the distinction between sincerity and mockery collapses. Ultimately, this article argues that stiob, trolling, and holy foolishness now constitute a transnational discursive formation reshaping public culture in the twenty-first century.
Journal Article
Cell Motility Dynamics in Glaucoma: Mechanisms, Pathogenic Roles, and Therapeutic Targeting
Cell motility—the dynamic process encompassing migration, adhesion modulation, cytoskeletal remodeling, and extracellular matrix (ECM) interactions—is fundamental to ocular homeostasis. In glaucoma, disrupted motility of trabecular meshwork (TM) and Schlemm’s canal (SC) cells contributes to impaired aqueous humor outflow and elevated intraocular pressure (IOP), while reactive motility of optic nerve head (ONH) glial cells promotes fibrosis and neurodegeneration. Mechanistically, TM/SC motility is regulated by Rho GTPase and ROCK signaling, focal adhesion dynamics, and ECM interactions, while glial cells respond to mechanical stress and cytokines such as TGF-β2. Cytoskeletal alterations, ECM stiffening, and endothelial–mesenchymal transition (EndMT) contribute to glaucomatous damage by reducing normal cell motility and tissue remodeling capacity. Aberrant motility at the ONH, including heterogeneous astrocytic reactivity, leads to lamina cribrosa remodeling and retinal ganglion cell degeneration. Therapeutically, ROCK inhibitors improve TM/SC motility and outflow, suppress EndMT, and may confer neuroprotection. Stem cell-based strategies and modulation of TGF-β2 or mechanotransduction pathways represent emerging approaches to restore physiological motility and regenerative potential. Despite promising advances, challenges remain in ensuring targeted, durable, and safe modulation of cellular dynamics. Understanding and therapeutically harnessing cell motility offers a unifying framework to address both pressure-dependent and neurodegenerative mechanisms in glaucoma.
Journal Article
Rho Kinase Inhibitors in Glaucoma Management: Current Perspectives and Future Directions
Glaucoma is a group of eye conditions characterised by optic nerve damage and visual field loss, representing the leading cause of irreversible blindness worldwide. Glaucoma exerts substantial global impact on visual impairment and blindness. The management of glaucoma has traditionally relied on medications such as prostaglandin analogs, beta-blockers, alpha agonists, and carbonic anhydrase inhibitors, which aim to lower intraocular pressure through various mechanisms. Rho kinase (ROCK) inhibitors have recently emerged as a novel class of antiglaucoma drugs, offering an alternative approach by enhancing aqueous humour outflow through the conventional pathway. Recent clinical studies assessing the efficacy and safety of Ripasudil (K-115) and Netarsudil (AR-13324) have demonstrated promising outcomes in the treatment of various types of glaucoma. Comparative studies have shown that ROCK inhibitors are non-inferior to traditional antiglaucomatous medications, such as beta-blockers and prostaglandins. Additionally, emerging evidence suggests their neuroprotective properties, which may play a role in preserving retinal ganglion cells. Furthermore, positive outcomes have been observed when these agents are used in conjunction with glaucoma filtering surgery, potentially enhancing surgical success rates. Adverse effects, including conjunctival hyperemia, cornea verticillata, conjunctivitis, and blepharitis, have been reported following the use of ROCK inhibitors. However, those side effects appear to be subtle in most cases. This review aims to provide an overview of ROCK inhibitors, focusing on their mechanisms of action, clinical efficacy, safety profiles, and additional benefits for eye health. Furthermore, further potential applications of ROCK inhibitors in glaucoma management are going to be discussed.
Journal Article
Laughing Mad
A rigorous analytic analysis,Laughing Madinterrogates notions of identity, within both the African American community and mainstream popular culture. Written in engaging and accessible prose, it is also a book that will travel from the seminar room, to the barbershop, to the kitchen table, allowing readers to experience the sketches, stand-up, and film comedies with all the laughter they deserve.
eBook
Mechanotransduction in trabecular meshwork cells: Rho/ROCK-dependent responses to substrate stiffness
Elevated intraocular pressure (IOP) is a major risk factor for glaucoma. Trabecular meshwork cells (TMCs) play a crucial role in modulating IOP by regulating the aqueous outflow resistance. In glaucoma, the stiffening of trabecular meshwork (TM) tissue is believed to affect aqueous humor outflow, highlighting the importance of substrate stiffness in influencing TMC behavior. However, the molecular mechanisms by which substrate stiffness impacts TMCs are still not fully understood. This study investigates the role of the Rho/ROCK pathway in the effect of substrate stiffness on TMCs. Human TMCs (hTMCs) and porcine TMCs (pTMCs) were cultured on substrates of varying stiffness with Rho/ROCK pathway inhibitor Y-27632 to assess the alterations in Rho/ROCK pathway molecules, cytoskeletal organization, and cellular functions. The results indicate that stiffer substrates generally lead to decreased ROCK levels, multi-oriented F-actin organization, increased cellular contraction, and enhanced cell migration. Notably, these effects were diminished or negated by Rho/ROCK pathway inhibition, which suggests that the Rho/ROCK pathway is at least partially responsible for mediating substrate stiffness affecting TMC behavior. This study highlights the significance of the mechano-microenvironment of the TM in glaucoma pathogenesis and deepens the understanding of the Rho/ROCK pathway as a promising therapeutic target for glaucoma treatment.
Journal Article
Teaching the 2016 Campaign through the Art of Parody
Kelley discusses the classroom exercise that offers strategies for introducing students in introductory-level college courses to campaign-themed music parodies. Here's the lesson objectives, define parody and investigate how it operates within campaign contexts, analyze the text and images (where applicable) in parodies and compare the original tune (and its target audience) to its parodied version (and its target audience) in order to consider questions of meaning and context. Also noted the selected list of parodies available on Youtube and questions which can be used to guide a classroom discussion on campaign parodies.
Journal Article
Humor's Brick: George Herriman's Krazy Kat
Schmitz presents Humor's Brick: George Herriman's Krazy Kat.
Journal Article