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result(s) for
"growth trait"
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High-density genetic map construction and quantitative trait loci identification for growth traits in (Taxodium distichum var. distichum × T. mucronatum) × T. mucronatum
Background
‘Zhongshanshan’ is the general designation for the superior interspecific hybrid clones of
Taxodium
species, which is widely grown for economic and ecological purposes in southern China. Growth is the priority objective in ‘Zhongshanshan’ tree improvement. A high-density linkage map is vital to efficiently identify key quantitative trait loci (QTLs) that affect growth.
Results
In total, 403.16 Gb of data, containing 2016,336 paired-end reads, was obtained after preprocessing. The average sequencing depth was 28.49 in
T. distichum
var.
distichum
, 25.18 in
T. mucronatum
, and 11.12 in each progeny. In total, 524,662 high-quality SLAFs were detected, of which 249,619 were polymorphic, and 6166 of the polymorphic markers met the requirements for use in constructing a genetic map. The final map harbored 6156 SLAF markers on 11 linkage groups, and was 1137.86 cM in length, with an average distance of 0.18 cM between adjacent markers. Separate QTL analyses of traits in different years by CIM detected 7 QTLs. While combining multiple-year data, 13 QTLs were detected by ICIM. 5 QTLs were repeatedly detected by the two methods, and among them, 3 significant QTLs (
q6–2
,
q4–2
and
q2–1
) were detected in at least two traits. Bioinformatic analysis discoveried a gene annotated as a leucine-rich repeat receptor-like kinase gene within
q4–2
.
Conclusions
This map is the most saturated one constructed in a Taxodiaceae species to date, and would provide useful information for future comparative mapping, genome assembly, and marker-assisted selection.
Journal Article
The power of relentless : 7 secrets to achieving mega-success, financial freedom, and the life of your dreams
\"Wayne Allyn Root, the 'Capitalist Evangelist' of Las Vegas, explains how he relentlessly pursued success in this motivational and inspirational guide for hopeful entrepreneurs and capitalists\"-- Provided by publisher.
Book
A longitudinal quantitative trait locus mapping of chicken growth traits
Since the growth traits of chickens are largely related to the production of meat and eggs, it is definitely important to understand genetic basis of growth traits. Although many quantitative trait loci (QTLs) that affect growth traits have recently been reported in chickens, little is known about genetic architecture of growth traits across all growth stages. Therefore, we conducted a longitudinal QTL study of growth traits measured from 0 to 64 weeks of age using 134 microsatellite DNA markers on 26 autosomes from 406 F2 females, which resulted from an intercross of Oh-Shamo and White Leghorn chicken breeds. We found 27 and 21 independent main-effect QTLs for body weight and shank length, respectively. Moreover, 15 and 4 pairs of epistatic QTLs were found for body weight and shank length, respectively. Taken together, the present study revealed 48 QTLs for growth traits on 21 different autosomes, and these loci clearly have age-specific effects on phenotypes throughout stages that are important for meat and egg productions. Approximately 60% of Oh-Shamo-derived alleles increased the phenotypic values, corresponding to the fact that Oh-Shamo traits were higher than those of White Leghorn. On the other hand, remaining Oh-Shamo alleles decreased the phenotypic values. Our results clearly indicated that the growth traits of chickens are regulated by several main and epistatic QTLs that are widely distributed in the chicken genome, and that the QTLs have age-dependent manners of controlling the traits. This study implies importance of not only cross-sectional but also longitudinal growth data for further understanding of the complex genetic architecture in animal.
Journal Article
Resilient : how to grow an unshakable core of calm, strength, and happiness
\"These days it's hard to count on the world outside. So it's vital to grow strengths inside like grit, gratitude, and compassion---the key to resilience, and to lasting well-being in a changing world. True resilience is much more than enduring terrible conditions. We need resilience every day to raise a family, work at a job, cope with stress, deal with health problems, navigate issues with others, heal from old pain, and simply keep on going. With his trademark blend of neuroscience, mindfulness, and positive psychology, New York Times bestselling author Dr. Rick Hanson shows you how to develop twelve vital inner strengths hardwired into your own nervous system. Then no matter what life throws at you, you'll be able to feel less stressed, pursue opportunities with confidence, and stay calm and centered in the face of adversity.\"--Dust jacket.
Book
Genome-wide association studies for growth traits in broilers
Background
The identification of markers and genes for growth traits may not only benefit for marker assist selection /genomic selection but also provide important information for understanding the genetic foundation of growth traits in broilers.
Results
In the current study, we estimated the genetic parameters of eight growth traits in broilers and carried out the genome-wide association studies for these growth traits. A total of 113 QTNs discovered by multiple methods together, and some genes, including
ACTA1
,
IGF2BP1
,
TAPT1
,
LDB2
,
PRKCA
,
TGFBR2
,
GLI3
,
SLC16A7, INHBA, BAMBI, APCDD1, GPR39,
and
GATA4
, were identified as important candidate genes for rapid growth in broilers.
Conclusions
The results of this study will provide important information for understanding the genetic foundation of growth traits in broilers.
Journal Article
The perfection trap : embracing the power of good enough
A highly regarded professor of psychology at the London School of Economics, sharing contemporary evidence, explores how the pursuit of perfection can lead to burnout and depression and shows what we can do to resist the modern-day pressure to be perfect to led a more purposeful and contented life.
Book
Genome-Wide Association Study of Growth and Body-Shape-Related Traits in Large Yellow Croaker (Larimichthys crocea) Using ddRAD Sequencing
Large yellow croaker (Larimichthys crocea) is an economically important marine fish species of China. Due to overfishing and marine pollution, the wild stocks of this croaker have collapsed in the past decades. Meanwhile, the cultured croaker is facing the difficulties of reduced genetic diversity and low growth rate. To explore the molecular markers related to the growth traits of croaker and providing the related SNPs for the marker-assisted selection, we used double-digest restriction-site associated DNA (ddRAD) sequencing to dissect the genetic bases of growth traits in a cultured population and identify the SNPs that associated with important growth traits by GWAS. A total of 220 individuals were genotyped by ddRAD sequencing. After quality control, 27,227 SNPs were identified in 220 samples and used for GWAS analysis. We identified 13 genome-wide significant associated SNPs of growth traits on 8 chromosomes, and the beta P of these SNPs ranged from 0.01 to 0.86. Through the definition of candidate regions and gene annotation, candidate genes related to growth were identified, including important regulators such as fgf18, fgf1, nr3c1, cyp8b1, fabp2, cyp2r1, ppara, and ccm2l. We also identified SNPs and candidate genes that significantly associated with body shape, including bmp7, col1a1, col11a2, and col18a1, which are also economically important traits for large yellow croaker aquaculture. The results provided insights into the genetic basis of growth and body shape in large yellow croaker population and would provide reliable genetic markers for molecular marker-assisted selection in the future. Meanwhile, the result established a basis for our subsequent fine mapping and related gene study.
Journal Article
Not yet : the story of an unstoppable skater
\"After watching an ice-skating movie, young Zahra sets her mind to learn how to ice skate even though her family and friends doubt her abilities. After all, she's too old to learn, the rink is too cold, and figure skaters don't look like her... not yet at least! Illustrated with Sara Alfageeh's energetic lines and colors that pop right off the page, we follow Zahra's story as she glides across the floors of her house in her socks all the way to the ice rink... and as she repeatedly says ''not yet'' to naysayers -- including herself -- who try to convince her to stop pursuing her dream. An inspiring tale of self-empowerment and perseverance as we see the refrain -- not yet -- grow from a low, meek mumble to a mantra and promise filled with determination\"-- Provided by publisher.
BOOK
Genetic and variation analyses of growth traits of half-sib Larix olgensis families in northeastern China
To gain a better understanding of genetic variation of growth traits in
Larix olgensis
, we investigated the progeny of 60 half-sib families of
L. olgensis
grown in a seed orchard in northeastern China. Tree height (H), basal diameter, and diameter at breast height (DBH) were measured at four different ages (i.e., at 4, 6, 8 and 10 years of growth). Significant differences among all the variation sources were observed during the different growth years. During the four measured years, phenotypic coefficients of variation (PCVs) of all traits ranged from 17.83 to 33.01 %, with heritabilities varying from 0.531 to 0.798. A correlation analysis uncovered extremely significant positive correlations among all traits within or among years. These high heritabilities and large PCVs were beneficial for the early selection of superior families. Using a comprehensive evaluation method, different families were selected as superior on the basis of different selection rates during each measured year, with families L78, L64, L63, L48, L13 and L14 selected across all measured years. At the 10th growth year, the optimal time to identify superior
L. olgensis
families, the selected families (L78, L64, L63, L48, L13 and L14) displayed higher H and DBH values, which corresponded to genetic gains of 8.31 and 16.82 %, respectively. In addition to the identification of superior female parents for improved seed orchard establishment, the findings generated by our study can serve as a theoretical foundation for early selection of
L. olgensis
families.
Journal Article