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Application of a minimally invasive full‐thickness autologous microcolumn skin harvesting device for donor site tissue collection and augmenting wound healing in a porcine wound model
by
Curtis, Brenda
,
Prevish, Brian
,
Goedegebuure, Madeleine
in
Animals
,
Disease Models, Animal
,
Fibroblasts
2024
Using a 6‐week porcine full‐thickness excisional wound grafting model, we evaluated the Autologous Regeneration of Tissue (ART®) System, a novel skin harvesting device designed to collect autologous full‐thickness autologous microcolumns (FTAM) at 0.5 mm in diameter. The donor skin sites were harvested using the ART® System and compared to split‐thickness skin grafts (STSGs). Recipient sites were divided into three treatment groups: FTAM, STSG and Untreated control. Comparing the FTAM donor sites to the STSG donor sites, we observed significantly faster re‐epithelization by Day 4 (p < 0.05), earlier adnexal structures and rete ridge formation by Week 3, and increased collagen and elastin content by Week 6. We also observed an increased rate of healing at the FTAM donor site whilst limiting donor site morbidity compared to traditional STSG donor sites. Time to recipient site closure was 2.4 weeks for STSG treated, 3.3 weeks for FTAM treated and 4.1 weeks for the Untreated control (p < 0.05). The STSG and FTAM recipient sites reached complete re‐epithelialization by Weeks 4 and 5, respectively which was significantly faster compared to the Untreated control. However, the FTAM recipient site received only 10% of the donor site tissue relative to the recipient site area and the amount of donor site tissue grafted on the STSG recipient sites was 5× more than the FTAM recipient sites. Additionally, the FTAMs harvested by the ART® System augmented recipient wound site healing as a result of ‘epithelial island’ expansion in contrast to Untreated control sites that closed primarily by contracture.
Journal Article
Regime shift in Arctic Ocean sea ice thickness
by
Sumata, Hiroshi
,
Gerland, Sebastian
,
de Steur, Laura
in
704/106/125
,
704/106/694/674
,
704/829/2737
2023
Manifestations of climate change are often shown as gradual changes in physical or biogeochemical properties1. Components of the climate system, however, can show stepwise shifts from one regime to another, as a nonlinear response of the system to a changing forcing2. Here we show that the Arctic sea ice regime shifted in 2007 from thicker and deformed to thinner and more uniform ice cover. Continuous sea ice monitoring in the Fram Strait over the last three decades revealed the shift. After the shift, the fraction of thick and deformed ice dropped by half and has not recovered to date. The timing of the shift was preceded by a two-step reduction in residence time of sea ice in the Arctic Basin, initiated first in 2005 and followed by 2007. We demonstrate that a simple model describing the stochastic process of dynamic sea ice thickening explains the observed ice thickness changes as a result of the reduced residence time. Our study highlights the long-lasting impact of climate change on the Arctic sea ice through reduced residence time and its connection to the coupled ocean–sea ice processes in the adjacent marginal seas and shelves of the Arctic Ocean.
Journal Article
Ice thickness distribution of all Swiss glaciers based on extended ground-penetrating radar data and glaciological modeling
by
Hellmann, Sebastian
,
Langhammer, Lisbeth
,
Hodel, Elias
in
Aerogeophysical measurements
,
Algorithms
,
Antennas
2021
Accurate knowledge of the ice thickness distribution and glacier bed topography is essential for predicting dynamic glacier changes and the future developments of downstream hydrology, which are impacting the energy sector, tourism industry and natural hazard management. Using AIR-ETH, a new helicopter-borne ground-penetrating radar (GPR) platform, we measured the ice thickness of all large and most medium-sized glaciers in the Swiss Alps during the years 2016–20. Most of these had either never or only partially been surveyed before. With this new dataset, 251 glaciers – making up 81% of the glacierized area – are now covered by GPR surveys. For obtaining a comprehensive estimate of the overall glacier ice volume, ice thickness distribution and glacier bed topography, we combined this large amount of data with two independent modeling algorithms. This resulted in new maps of the glacier bed topography with unprecedented accuracy. The total glacier volume in the Swiss Alps was determined to be 58.7 ± 2.5 km3 in the year 2016. By projecting these results based on mass-balance data, we estimated a total ice volume of 52.9 ± 2.7 km3 for the year 2020. Data and modeling results are accessible in the form of the SwissGlacierThickness-R2020 data package.
Journal Article
A consensus estimate for the ice thickness distribution of all glaciers on Earth
by
Maussion Fabien
,
Huss Matthias
,
Machguth Horst
in
Antarctic ice sheet
,
Distribution
,
Dynamics
2019
Knowledge of the ice thickness distribution of the world’s glaciers is a fundamental prerequisite for a range of studies. Projections of future glacier change, estimates of the available freshwater resources or assessments of potential sea-level rise all need glacier ice thickness to be accurately constrained. Previous estimates of global glacier volumes are mostly based on scaling relations between glacier area and volume, and only one study provides global-scale information on the ice thickness distribution of individual glaciers. Here we use an ensemble of up to five models to provide a consensus estimate for the ice thickness distribution of all the about 215,000 glaciers outside the Greenland and Antarctic ice sheets. The models use principles of ice flow dynamics to invert for ice thickness from surface characteristics. We find a total volume of 158 ± 41 × 103 km3, which is equivalent to 0.32 ± 0.08 m of sea-level change when the fraction of ice located below present-day sea level (roughly 15%) is subtracted. Our results indicate that High Mountain Asia hosts about 27% less glacier ice than previously suggested, and imply that the timing by which the region is expected to lose half of its present-day glacier area has to be moved forward by about one decade.The ice volume of glaciers outside the Greenland and Antarctic ice sheets totals about 158,000 km3, with about 27% less ice in High Mountain Asia than thought, according to multiple models that estimate ice thickness from surface characteristics.
Journal Article
Arctic sea ice thickness, volume, and multiyear ice coverage: losses and coupled variability (1958-2018)
2018
Large-scale changes in Arctic sea ice thickness, volume and multiyear sea ice (MYI) coverage with available measurements from submarine sonars, satellite altimeters (ICESat and CryoSat-2), and satellite scatterometers are summarized. The submarine record spans the period between 1958 and 2000, the satellite altimeter records between 2003 and 2018, and the scatterometer records between 1999 and 2017. Regional changes in ice thickness (since 1958) and within the data release area of the Arctic Ocean, previously reported by Kwok and Rothrock (2009 Geophys. Res. Lett. 36 L15501), have been updated to include the 8 years of CryoSat-2 (CS-2) retrievals. Between the pre-1990 submarine period (1958-1976) and the CS-2 period (2011-2018) the average thickness near the end of the melt season, in six regions, decreased by 2.0 m or some 66% over six decades. Within the data release area (∼38% of the Arctic Ocean) of submarine ice draft, the thinning of ∼1.75 m in winter since 1980 (maximum thickness of 3.64 m in the regression analysis) has not changed significantly; the mean thickness over the CS-2 period is ∼2 m. The 15 year satellite record depicts losses in sea ice volume at 2870 km3/decade and 5130 km3/decade in winter (February-March) and fall (October-November), respectively: more moderate trends compared to the sharp decreases over the ICESat period, where the losses were weighted by record-setting melt in 2007. Over the scatterometer record (1999-2017), the Arctic has lost more than 2 × 106 km2 of MYI-a decrease of more than 50%; MYI now covers less than one-third of the Arctic Ocean. Independent MYI coverage and volume records co-vary in time, the MYI area anomalies explain ∼85% of the variance in the anomalies in Arctic sea ice volume. If losses of MYI continue, Arctic thickness/volume will be controlled by seasonal ice, suggesting that the thickness/volume trends will be more moderate (as seen here) but more sensitive to climate forcing.
Journal Article
Ice velocity and thickness of the world’s glaciers
by
Millan, Romain
,
Rabatel, Antoine
,
Morlighem, Mathieu
in
704/106/125
,
704/106/694
,
704/106/694/1108
2022
The effect of climate change on water resources and sea-level rise is largely determined by the size of the ice reservoirs around the world and the ice thickness distribution, which remains uncertain. Here, we present a comprehensive high-resolution mapping of ice motion for 98% of the world’s total glacier area during the period 2017–2018. We use this mapping of glacier flow to generate an estimate of global ice volume that reconciles ice thickness distribution with glacier dynamics and surface topography. After reallocating volume connected to the Antarctic ice sheet, the results suggest that the world’s glaciers have a potential contribution to sea-level rise of 257 ± 85 mm, which is 20% less than previously estimated. At low latitudes, our findings highlight notable changes in freshwater resources, with 34% more ice in the Himalayas and 27% less ice in the tropical Andes of South America, affecting water availability for local populations. This mapping of glacier flow and thickness redefines our understanding of global ice-volume distribution and has implications for the prediction of glacier evolution around the world, since accurate representations of glacier geometry and dynamics are of prime importance to glacier modelling.
Potential sea-level rise from the world’s glaciers is 20% less than previously thought, according to an estimate based on high-resolution maps of glacier ice velocity and thickness.
Journal Article
Seasonal Prediction and Predictability of Regional Antarctic Sea Ice
by
Delworth, Thomas
,
Rosati, Anthony
,
Johnson, Nathaniel C.
in
Anomalies
,
Antarctic sea ice
,
Arctic sea ice
2021
Compared to the Arctic, seasonal predictions of Antarctic sea ice have received relatively little attention. In this work, we utilize three coupled dynamical prediction systems developed at the Geophysical Fluid Dynamics Laboratory to assess the seasonal prediction skill and predictability of Antarctic sea ice. These systems, based on the FLOR, SPEAR_LO, and SPEAR_MED dynamical models, differ in their coupled model components, initialization techniques, atmospheric resolution, and model biases. Using suites of retrospective initialized seasonal predictions spanning 1992–2018, we investigate the role of these factors in determining Antarctic sea ice prediction skill and examine the mechanisms of regional sea ice predictability. We find that each system is capable of skillfully predicting regional Antarctic sea ice extent (SIE) with skill that exceeds a persistence forecast. Winter SIE is skillfully predicted 11 months in advance in the Weddell, Amundsen/Bellingshausen, Indian, and west Pacific sectors, whereas winter skill is notably lower in the Ross sector. Zonally advected upper-ocean heat content anomalies are found to provide the crucial source of prediction skill for the winter sea ice edge position. The recently developed SPEAR systems are more skillful than FLOR for summer sea ice predictions, owing to improvements in sea ice concentration and sea ice thickness initialization. Summer Weddell SIE is skillfully predicted up to 9 months in advance in SPEAR_MED, due to the persistence and drift of initialized sea ice thickness anomalies from the previous winter. Overall, these results suggest a promising potential for providing operational Antarctic sea ice predictions on seasonal time scales.
Journal Article
The Challenges of Remotely Measuring Oil Slick Thickness
2018
The thickness of oil spills on the sea is an important but poorly studied topic. Means to measure slick thickness are reviewed. More than 30 concepts are summarized. Many of these are judged not to be viable for a variety of scientific reasons. Two means are currently available to remotely measure oil thickness, namely, passive microwave radiometry and time of acoustic travel. Microwave radiometry is commercially developed at this time. Visual means to ascertain oil thickness are restricted by physics to thicknesses smaller than those of rainbow sheens, which rarely occur on large spills, and thin sheen. One can observe that some slicks are not sheen and are probably thicker. These three thickness regimes are not useful to oil spill countermeasures, as most of the oil is contained in the thick portion of a slick, the thickness of which is unknown and ranges over several orders of magnitude. There is a continuing need to measure the thickness of oil spills. This need continues to increase with time, and further research effort is needed. Several viable concepts have been developed but require further work and verification. One of the difficulties is that ground truthing and verification methods are generally not available for most thickness measurement methods.
Journal Article
A year-round satellite sea-ice thickness record from CryoSat-2
by
Aksenov, Yevgeny
,
Krumpen, Thomas
,
Landy, Jack C.
in
704/106/125
,
704/106/694/2786
,
Algorithms
2022
Arctic sea ice is diminishing with climate warming
1
at a rate unmatched for at least 1,000 years
2
. As the receding ice pack raises commercial interest in the Arctic
3
, it has become more variable and mobile
4
, which increases safety risks to maritime users
5
. Satellite observations of sea-ice thickness are currently unavailable during the crucial melt period from May to September, when they would be most valuable for applications such as seasonal forecasting
6
, owing to major challenges in the processing of altimetry data
7
. Here we use deep learning and numerical simulations of the CryoSat-2 radar altimeter response to overcome these challenges and generate a pan-Arctic sea-ice thickness dataset for the Arctic melt period. CryoSat-2 observations capture the spatial and the temporal patterns of ice melting rates recorded by independent sensors and match the time series of sea-ice volume modelled by the Pan-Arctic Ice Ocean Modelling and Assimilation System reanalysis
8
. Between 2011 and 2020, Arctic sea-ice thickness was 1.87 ± 0.10 m at the start of the melting season in May and 0.82 ± 0.11 m by the end of the melting season in August. Our year-round sea-ice thickness record unlocks opportunities for understanding Arctic climate feedbacks on different timescales. For instance, sea-ice volume observations from the early summer may extend the lead time of skilful August–October sea-ice forecasts by several months, at the peak of the Arctic shipping season.
Deep learning and numerical simulations of CryoSat-2 radar altimeter data are used to generate a pan-Arctic sea-ice thickness dataset for the Arctic melt period.
Journal Article
Snow Depth on Arctic Sea Ice Retrieval Using a Synergy of Sentinel‐3's Active and Passive Microwave Instruments
2026
Snow depth remains one of the largest sources of uncertainty in satellite‐derived sea ice thickness (SIT). Here, we introduce the novel Nadir Radiometer and Radar Synergy (NaRRS) method that combines data from Sentinel‐3's Microwave Radiometer (MWR) and Synthetic Aperture Radar Altimeter (SRAL) to retrieve Arctic snow depth on sea ice. The resultant snow depths are co‐located with SRAL‐derived radar freeboard, reducing spatio‐temporal mismatches in SIT processing. NaRRS achieves an R2${\\mathrm{R}}^{2}$of 0.72 and RMSE of 0.05 m in cross‐validation against Operation IceBridge snow depth data, and better matches IceBird observations than the modified Warren Climatology (mW99). Ice drafts estimated from coupled snow depth and freeboard align with mW99 against Beaufort Sea moorings but reduce bias by up to 50% against Fram Strait moorings. This work provides a proof‐of‐concept for simultaneous, co‐located snow depth and SIT retrievals, paving the way for next‐generation satellite missions and retrieval frameworks.
Journal Article