Explore the vast range of titles available.

The increasing resistance of pathogenic bacteria to antibiotics is a challenging worldwide health problem that has led to the search for new and more efficient antibacterial agents. Nanotechnology has proven to be an effective tool for the fight against bacteria. In this paper, we present the synthesis and traits of trimetal (CuZnFe) oxide nanoparticles (NPs) using X-ray diffraction, high-resolution transmission electron microscopy, and energy dispersive x-ray spectroscopy. We evaluated the antibacterial activity of these NPs against gram-negative and gram-positive and then compared it to that of their pure single-metal oxide components CuO and ZnO. Our study showed that the antibacterial activity of the trimetal oxide NPs was greater against . than against . . Overall, the antimicrobial effect of trimetal NPs is between those of pure ZnO and CuO nanoparticles, which may mean that their cytotoxicity is also between that of pure ZnO and CuO NPs, making them potential antibiotics. However, the cytotoxicity of trimetal NPs to mammalian cells needs to be verified. The combination of three metal oxide NPs (ZnO, CuO, and Fe O ) in one multimetal (CuZnFe) oxide NPs will enhance the therapeutic strategy against a wide range of microbial infections. Bacteria are unlikely to develop resistance against this new NP because bacteria must go through a series of mutations to become resistant to the trimetal oxide NP. Therefore, this NP can combat existing and emerging bacterial infections.

A novel copper-zinc-manganese trimetal oxide nanocomposite was synthesized by the simple co-precipitation method for sensing glucose and methylene blue degradation. The absorption maximum was found by ultraviolet–visible spectroscopy (UV-Vis) analysis, and the bandgap was 4.32 eV. The formation of a bond between metal and oxygen was confirmed by Fourier Transform Infrared Spectroscopy (FT-IR) analysis. The average crystallite size was calculated as 17.31 nm by X-ray powder diffraction (XRD) analysis. The morphology was observed as spherical by scanning electron microscope (SEM) and high-resolution transmission electron microscopy (HR-TEM) analysis. The elemental composition was determined by Energy Dispersive X-ray Analysis (EDAX) analysis. The oxidation state of the metals present in the nanocomposites was confirmed by the X-ray photoelectron spectroscopy (XPS) analysis. The hydrodynamic diameter and zeta potential of the nanocomposite were 218 nm and −46.8 eV, respectively. The thermal stability of the nanocomposite was analyzed by thermogravimetry-differential scanning calorimetry (TG-DSC) analysis. The synthesized nanocomposite was evaluated for the electrochemical glucose sensor. The nanocomposite shows 87.47% of degradation ability against methylene blue dye at a 50 µM concentration. The trimetal oxide nanocomposite shows potent activity against Escherichia coli. In addition to that, the prepared nanocomposite shows strong antioxidant application where scavenging activity was observed to be 76.58 ± 0.30, 76.89 ± 0.44, 81.41 ± 30, 82.58 ± 0.32, and 84.36 ± 0.09 % at 31, 62, 125, 250, and 500 µg/mL, respectively. The results confirm the antioxidant potency of nanoparticles (NPs) was concentration dependent.