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Association between Bioactive Molecules in Breast Milk and Type 1 Diabetes Mellitus
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Journal Article
Association between Bioactive Molecules in Breast Milk and Type 1 Diabetes Mellitus
2020
Overview
The association between breastfeeding and type 1 diabetes mellitus (T1DM) is controversial. However,
several recent studies have established a link between these two factors, necessitating a need to review this subject
to raise public awareness. Current research indicates that breast milk contains a variety of bioactive substances
including immunoglobulins, oligosaccharides, insulin, lactoferrin, lysozyme, cytokines, epidermal growth factors,
leukocytes, nucleotides, beneficial bacteria and vitamins. Such substances strengthen the breastfeeding infant’s
immune system, both directly, by increasing gut microbiota diversity and attacking harmful bacteria and proinflammatory molecules, and indirectly, by increasing thymus performance. Accordingly, a lack of or inadequate
breastfeeding may predispose infants to several autoimmune disorders, including T1DM. Nursing mothers and
caregivers are therefore advised to follow optimal breastfeeding practices prior to introducing complementary foods.
Publisher
Sultan Qaboos Uinversity : Academic Publication Board,Sultan Qaboos University, College of Medicine and Health Sciences,Sultan Qaboos University,Sultan Qaboos University Medical Journal, College of Medicine & Health Sciences
