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Exercise and Bone Mineral Density in Premenopausal Women: A Meta-Analysis of Randomized Controlled Trials
by
Kohrt, Wendy M.
, Kelley, Kristi S.
, Kelley, George A.
in
Analysis
/ Bone density
/ Bones
/ Clinical trials
/ Density
/ Endocrinology
/ Exercise
/ Health aspects
/ Intervention
/ Menopause
/ Meta-analysis
/ Osteoporosis
/ Physical fitness
/ Review
/ Strength training
/ Studies
2013
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Exercise and Bone Mineral Density in Premenopausal Women: A Meta-Analysis of Randomized Controlled Trials
by
Kohrt, Wendy M.
, Kelley, Kristi S.
, Kelley, George A.
in
Analysis
/ Bone density
/ Bones
/ Clinical trials
/ Density
/ Endocrinology
/ Exercise
/ Health aspects
/ Intervention
/ Menopause
/ Meta-analysis
/ Osteoporosis
/ Physical fitness
/ Review
/ Strength training
/ Studies
2013
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Do you wish to request the book?
Exercise and Bone Mineral Density in Premenopausal Women: A Meta-Analysis of Randomized Controlled Trials
by
Kohrt, Wendy M.
, Kelley, Kristi S.
, Kelley, George A.
in
Analysis
/ Bone density
/ Bones
/ Clinical trials
/ Density
/ Endocrinology
/ Exercise
/ Health aspects
/ Intervention
/ Menopause
/ Meta-analysis
/ Osteoporosis
/ Physical fitness
/ Review
/ Strength training
/ Studies
2013
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Exercise and Bone Mineral Density in Premenopausal Women: A Meta-Analysis of Randomized Controlled Trials
Journal Article
Exercise and Bone Mineral Density in Premenopausal Women: A Meta-Analysis of Randomized Controlled Trials
2013
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Overview
Objective. Examine the effects of exercise on femoral neck (FN) and lumbar spine (LS) bone mineral density (BMD) in premenopausal women. Methods. Meta-analysis of randomized controlled exercise trials ≥24 weeks in premenopausal women. Standardized effect sizes (g) were calculated for each result and pooled using random-effects models, Z score alpha values, 95% confidence intervals (CIs), and number needed to treat (NNT). Heterogeneity was examined using Q and I2. Moderator and predictor analyses using mixed-effects ANOVA and simple metaregression were conducted. Statistical significance was set at P≤0.05. Results. Statistically significant improvements were found for both FN (7g's, 466 participants, g=0.342, 95% CI=0.132, 0.553, P=0.001, Q=10.8, P=0.22, I2=25.7%, NNT=5) and LS (6g's, 402 participants, g=0.201, 95% CI=0.009, 0.394, P=0.04, Q=3.3, P=0.65, I2=0%, NNT=9) BMD. A trend for greater benefits in FN BMD was observed for studies published in countries other than the United States and for those who participated in home versus facility-based exercise. Statistically significant, or a trend for statistically significant, associations were observed for 7 different moderators and predictors, 6 for FN BMD and 1 for LS BMD. Conclusions. Exercise benefits FN and LS BMD in premenopausal women. The observed moderators and predictors deserve further investigation in well-designed randomized controlled trials. Erratum to “Exercise and Bone Mineral Density in Premenopausal Women: A Meta-Analysis of Randomized Controlled Trials”dx.doi.org/10.1155/2013/583217
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