Asset Details
Do you wish to reserve the book?
THU0383 Performance of musculoskeletal involvement of systemic lupus erythematosis: an ultrasound study in 114 patients
Hey, we have placed the reservation for you!
By the way, why not check out events that you can attend while you pick your title.
Oops! Something went wrong.
Looks like we were not able to place the reservation. Kindly try again later.
Are you sure you want to remove the book from the shelf?
THU0383 Performance of musculoskeletal involvement of systemic lupus erythematosis: an ultrasound study in 114 patients
Do you wish to request the book?
THU0383 Performance of musculoskeletal involvement of systemic lupus erythematosis: an ultrasound study in 114 patients
Please be aware that the book you have requested cannot be checked out. If you would like to checkout this book, you can reserve another copy
We have requested the book for you!
Your request is successful and it will be processed during the Library working hours. Please check the status of your request in My Requests.
Oops! Something went wrong.
Looks like we were not able to place your request. Kindly try again later.
Journal Article
THU0383 Performance of musculoskeletal involvement of systemic lupus erythematosis: an ultrasound study in 114 patients
2018
Overview
BackgroundJoints are commonly involved in systemic lupus erythematosus (SLE). Ultrasound (US) has been widely used in rheumatoid arthritis (RA), however rarely applied and studied in SLE.ObjectivesTo investigate the ultrasonic changes of the symptomatic joints and their correlations with clinical manifestations in SLE patients.Methods114 SLE patients who complained of arthralgia or arthritis from May 2014 to Aug 2017 and 15 Rhupus patients due to overlapping with RA were recruited for ultrasound evaluation. Ultrasound scan of the symptomatic joint areas was completed. The correlation between ultrasonographic changes and clinical characteristics was analysed. Besides that, US changes of bilateral wrists and hands of Rhupus patients were compared with those of the SLE patients.ResultsIn a total of 1866 joints scanned, synovial hyperplasia, tenosynovitis, erosion and osteophytes were all observed. Synovial hyperplasia was more often observed in knees in 28.6% patients (12/42), ankles in 25% patients (7/28), wrists in 23.3% patients (23/69) and elbows in 20% patients (5/25). Tenosynovitis and erosion were most commonly found in shoulders in 35% (7/20) and 65% (13/20) patients. Osteophytes were more common in proximal interphalangeal (PIP) joints, elbows and knees. Among 69 patients with 22 joints (bilateral wrists and hands) scanned, synovial hyperplasia was observed in 25 patients (36.2%) and erosion in 22 patients (31.8%). The agreement between synovial hyperplasia and swollen joints in PIP was fair (κ=0.633, p<0.01), however poor in wrists (κ=0.089, p=0.584). 18.4% patients with synovial hyperplasia had no tenderness or swollen clinically, while 15.7% patients with tenderness or swollen had no synovial hyperplasia on ultrasound. No correlation was found between ultrasound changes with SLE disease activity index. Both synovial hyperplasia and erosion were more common in Rhupus patients (73.3% vs. 36.2%, p=0.08; 66.7% vs. 26.0%, p=0.03) with significantly higher GS score (7.4±6.4 vs.1.6±4.1, p=0.04) than SLE alone patients.ConclusionsVariety of changes can be observed by ultrasound at different joints in SLE patients. The ultrasonographic changes and clinical manifestations did not always correspond to each other. Synovial hyperplasia and erosion was more common in Rhupus patients.Disclosure of InterestNone declared
Publisher
Elsevier Limited
Subject
