Asset Details
Do you wish to reserve the book?
Assessment of potential particulate contamination in intravenous solutions in an adult intensive care unit: a targeted correlation analysis
Hey, we have placed the reservation for you!
By the way, why not check out events that you can attend while you pick your title.
Oops! Something went wrong.
Looks like we were not able to place the reservation. Kindly try again later.
Are you sure you want to remove the book from the shelf?
Assessment of potential particulate contamination in intravenous solutions in an adult intensive care unit: a targeted correlation analysis
Do you wish to request the book?
Assessment of potential particulate contamination in intravenous solutions in an adult intensive care unit: a targeted correlation analysis
Please be aware that the book you have requested cannot be checked out. If you would like to checkout this book, you can reserve another copy
We have requested the book for you!
Your request is successful and it will be processed during the Library working hours. Please check the status of your request in My Requests.
Oops! Something went wrong.
Looks like we were not able to place your request. Kindly try again later.
Journal Article
Assessment of potential particulate contamination in intravenous solutions in an adult intensive care unit: a targeted correlation analysis
2025
Overview
BackgroundIntravenous drug administration is essential in intensive care treatment. However, the risk of particulate contamination in infusion solutions during treatment is often underestimated.MethodsResidual amounts of infusion solutions prepared and administered at the adult intensive care unit were examined for visible and subvisible particles according to the recommendations of the European Pharmacopoeia monographs 2.9.19 and 2.9.20.ResultsSamples from 169 infusion solutions were collected, 149 of which could be analysed. The Pharmacopoeia requirements for visible particles were not fulfilled in 42.9% (n=64/149) of the samples, while the requirements for subvisible particles were not met in 4.7% (n=7/149). A specific correlation between the pharmaceutical drugs or within the infusion set (bottle vs connected infusion line) and particulate contamination was not possible as the sample was too small for a correlation analysis. A Spearman rho analysis showed no correlation between particle contamination and administration mode (subvisible (10 µm): p=0.969, r=−0.005; subvisible (25 µm): p=0.834, r=−0.026; visible: p=0.711, r=−0.047) and particle contamination and dosage form (subvisible (10 µm): p=0.291, r=−0.092; subvisible (25 µm): p=0.513, r=0.057; visible: p=0.415, r=0.071).ConclusionsThis study showed that residuals of intravenously administered solutions have particulate contaminations. A specific causal factor was not identified.
Publisher
British Medical Journal Publishing Group,BMJ Publishing Group LTD
Subject
/ Patients
