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Treatment of HIV associated cerebral vasculopathy
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Treatment of HIV associated cerebral vasculopathy
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Journal Article
Treatment of HIV associated cerebral vasculopathy
2009
Overview
Cutfield and colleagues 1 demonstrate several useful practice points in their description of a man with advanced human immunodeficiency virus (HIV) infection and HIV associated cerebral vasculopathy who recovered with highly active antiretroviral therapy (HAART) (see page 936 ). Previous studies have demonstrated leucocytoclastic vasculitis of the vasa vasorum in extracranial carotid arteries and intimal abnormalities in intracranial medium sized vessels, and have hypothesised breakdown of the blood brain barrier as a cause for small vessel disease. 2 - 4 The vasculopathy may be asymptomatic, result in stroke, encephalopathy, cognitive impairment or non-specific neurological symptoms.
Publisher
BMJ Publishing Group Ltd,BMJ Publishing Group LTD
