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Journal Article
HBV + HCV = HCC?
1999
Overview
Both hepatitis B virus (HBV) and HCV are transmitted parenterally and coinfection is not uncommon, particularly in intravenous drug users and in countries with a high prevalence of HBV infection. 2 Coinfection with evidence of chronic HBV and HCV seems to result in more severe liver disease than either infection alone, 3 with an increased risk of liver cancer 2 and probably an increased risk of fulminant hepatitis when superinfection with HCV occurs on the background of chronic HBV. 4 The presence of hepatitis B surface and/or hepatitis B core antibodies (anti-HBs and anti-HBc) in the absence of hepatitis B surface antigen (HBsAg) is generally taken to indicate resolution of infection and provides evidence of previous HBV infection.
Publisher
BMJ Publishing Group LTD
Subject
Carcinoma, Hepatocellular - immunology
/ Carcinoma, Hepatocellular - virology
/ DNA
/ Hepatitis B virus - immunology
/ Hepatitis B, Chronic - complications
/ Hepatitis B, Chronic - immunology
/ Hepatitis C, Chronic - complications
/ Hepatitis C, Chronic - immunology
/ Humans
