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Congenital tuberculosis presenting as otorrhoea in a preterm infant

by Aldana-Aguirre, Jose Carlos , Landry, Marc-Antoine , El-Hakim, Hamdy , Phillipos, Ernest

in Abscesses / Age / Antibiotics / Asymptomatic / Biopsy / Case reports / Cerebrospinal fluid / Congenital diseases / Consent / Debridement / Diagnosis, Differential / Ear diseases / Ears & hearing / Facial Paralysis - microbiology / Fetuses / Gestational Age / Granulomas / Hearing loss / Humans / Infant, Newborn / Infant, Premature, Diseases - microbiology / Lesions / Lungs / Lymphatic system / Male / Medical personnel / Mortality / Mycobacterium tuberculosis / Neck / neonatal and paediatric intensive care / neonatal health / Neurological disorders / Newborn babies / Osteomyelitis - diagnosis / Osteomyelitis - microbiology / Otitis Media - diagnosis / Otitis Media - microbiology / Pediatrics / Postpartum period / Premature babies / Rare Disease / Staphylococcus infections / Streptococcus infections / Temporal Lobe - microbiology / Tuberculosis / Tuberculosis - complications / Tuberculosis - congenital / Tuberculosis - diagnosis / Tuberculosis, Lymph Node - congenital / Tuberculosis, Lymph Node - diagnosis

2018

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Congenital tuberculosis presenting as otorrhoea in a preterm infant

by Aldana-Aguirre, Jose Carlos , Landry, Marc-Antoine , El-Hakim, Hamdy , Phillipos, Ernest

2018

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Congenital tuberculosis presenting as otorrhoea in a preterm infant

by Aldana-Aguirre, Jose Carlos , Landry, Marc-Antoine , El-Hakim, Hamdy , Phillipos, Ernest

2018

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Journal Article

Congenital tuberculosis presenting as otorrhoea in a preterm infant

Aldana-Aguirre, Jose Carlos,

Landry, Marc-Antoine,

El-Hakim, Hamdy,

Phillipos, Ernest

2018

Overview

A premature infant of 25 weeks’ gestational age presented at 8 weeks after birth with otorrhoea from the left ear. Following a course of topical and systemic antibiotics, the patient deteriorated developing facial nerve paralysis and cervical lymphadenitis. Contrast-enhanced CT and MRI of the head showed a destructive process of the left temporal bone. These findings prompted the clinicians to send swabs from the purulent discharge from the ear for acid-fast bacilli stain. Furthermore, surgical exploration and debridement were undertaken. Cultures from ear discharge and biopsy—taken during surgical procedure—revealed the presence of Mycobacterium tuberculosis complex. The patient developed necrotizing otitis media, left temporal bone osteomyelitis and cervical lymphadenitis. The infant’s mother was found to have an endometrial biopsy positive for M. tuberculosis suggesting the diagnosis of congenital tuberculosis.

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Publisher

BMJ Publishing Group Ltd,BMJ Publishing Group LTD,BMJ Publishing Group

Subject

/ Age

/ Biopsy

/ Cerebrospinal fluid