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Assessment of the clinical and virological protection provided by a commercial inactivated bovine viral diarrhoea virus genotype 1 vaccine against a BVDV genotype 2 challenge
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Assessment of the clinical and virological protection provided by a commercial inactivated bovine viral diarrhoea virus genotype 1 vaccine against a BVDV genotype 2 challenge
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Journal Article
Assessment of the clinical and virological protection provided by a commercial inactivated bovine viral diarrhoea virus genotype 1 vaccine against a BVDV genotype 2 challenge
2003
Overview
A new genotype of bovine viral diarrhoea virus (BvDv), designated BVDV-2, has emerged in the last decade and in recent years the prevalence of BVDV-2 strains has increased. A vaccination-challenge study was carried out to determine the cross-protective efficacy of a commercial inactivated vaccine containing a BVDV-1 strain. A group of five BVDv-free calves was vaccinated twice and a second group of five calves served as negative controls. Two months after the first vaccination, all the calves were challenged intranasally with BVDV-2 strain BVD890. The clinical signs of disease, the changes in haematological variables and the level of viraemia were significantly less in the vaccinated group.
Publisher
BMJ Publishing Group Limited,Blackwell Publishing Ltd,British Veterinary Assoc
Subject
/ Animals
/ Bovine viral diarrhea virus 1
/ Bovine Virus Diarrhea-Mucosal Disease - prevention & control
/ calves
/ Cattle
/ Diarrhea Virus 1, Bovine Viral - genetics
/ Diarrhea Virus 1, Bovine Viral - isolation & purification
/ Genotype
/ Male
/ Médecine vétérinaire & santé animale
/ Veterinary medicine & animal health
/ Viral Vaccines - therapeutic use
/ viremia
