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Expression and modulation of adipolin/C1qdc2: a novel adipokine in human and murine ATDC-5 chondrocyte cell line

by Pino, Jesús , Scotece, Morena , Gómez, Rodolfo , Conde, Javier , Gualillo, Oreste , Lago, Francisca , Gómez-Reino, Juan Jesús , López, Verónica

in Adipokines - genetics / Adipokines - metabolism / Animals / Biological and medical sciences / Cell Differentiation - physiology / Cell Line / Chondrocytes - cytology / Chondrocytes - metabolism / Diseases of the osteoarticular system / Gene expression / Gene Expression Regulation / Humans / Medical sciences / Mice / Obesity / Reverse Transcriptase Polymerase Chain Reaction / RNA, Messenger - analysis / Rodents

2013

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Expression and modulation of adipolin/C1qdc2: a novel adipokine in human and murine ATDC-5 chondrocyte cell line

by Pino, Jesús , Scotece, Morena , Gómez, Rodolfo , Conde, Javier , Gualillo, Oreste , Lago, Francisca , Gómez-Reino, Juan Jesús , López, Verónica

2013

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Expression and modulation of adipolin/C1qdc2: a novel adipokine in human and murine ATDC-5 chondrocyte cell line

by Pino, Jesús , Scotece, Morena , Gómez, Rodolfo , Conde, Javier , Gualillo, Oreste , Lago, Francisca , Gómez-Reino, Juan Jesús , López, Verónica

2013

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Journal Article

Expression and modulation of adipolin/C1qdc2: a novel adipokine in human and murine ATDC-5 chondrocyte cell line

Pino, Jesús,

Scotece, Morena,

Gómez, Rodolfo,

Conde, Javier,

Gualillo, Oreste,

Lago, Francisca,

Gómez-Reino, Juan Jesús,

López, Verónica

2013

Overview

Here we describe, for the first time, adipolin expression in human chondrocytes as well as the intracellular mechanism involved in its regulation. [...]we show that adipolin expression is modulated by pro- and anti-inflammatory factors in chondrocytes.

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Publisher

BMJ Publishing Group Ltd and European League Against Rheumatism,BMJ Publishing Group,Elsevier Limited

Subject

Adipokines - genetics

/ Adipokines - metabolism

/ Animals

/ Biological and medical sciences

/ Cell Differentiation - physiology

/ Cell Line

/ Chondrocytes - cytology