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Prostate involvement during sexually transmitted infections as measured by prostate-specific antigen concentration
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Prostate involvement during sexually transmitted infections as measured by prostate-specific antigen concentration
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Journal Article
Prostate involvement during sexually transmitted infections as measured by prostate-specific antigen concentration
2011
Overview
Background:
We investigated prostate involvement during sexually transmitted infections by measuring serum prostate-specific antigen (PSA) as a marker of prostate infection, inflammation, and/or cell damage in young, male US military members.
Methods:
We measured PSA before and during infection for 299 chlamydia, 112 gonorrhoea, and 59 non-chlamydial, non-gonococcal urethritis (NCNGU) cases, and 256 controls.
Results:
Chlamydia and gonorrhoea, but not NCNGU, cases were more likely to have a large rise (⩾40%) in PSA than controls (33.6%, 19.1%, and 8.2%
vs
8.8%,
P
<0.0001, 0.021, and 0.92, respectively).
Conclusion:
Chlamydia and gonorrhoea may infect the prostate of some infected men.
Publisher
Nature Publishing Group UK,Nature Publishing Group
Subject
/ Adult
/ Antigens
/ Biological and medical sciences
/ Biomedical and Life Sciences
/ Chlamydia Infections - blood
/ Chlamydia Infections - epidemiology
/ Humans
/ Male
/ Military Personnel - statistics & numerical data
/ Oncology
/ Prostate-Specific Antigen - analysis
/ Prostate-Specific Antigen - blood
/ Sexually transmitted diseases
/ Sexually Transmitted Diseases - blood
/ Sexually Transmitted Diseases - epidemiology
/ Sexually Transmitted Diseases - etiology
/ Sexually Transmitted Diseases - transmission
/ STD
/ Tumors
