Asset Details
Do you wish to reserve the book?
Clinical symptoms and associated vascular imaging findings in Takayasu’s arteritis compared to giant cell arteritis
Hey, we have placed the reservation for you!
By the way, why not check out events that you can attend while you pick your title.
Oops! Something went wrong.
Looks like we were not able to place the reservation. Kindly try again later.
Are you sure you want to remove the book from the shelf?
Clinical symptoms and associated vascular imaging findings in Takayasu’s arteritis compared to giant cell arteritis
Do you wish to request the book?
Clinical symptoms and associated vascular imaging findings in Takayasu’s arteritis compared to giant cell arteritis
Please be aware that the book you have requested cannot be checked out. If you would like to checkout this book, you can reserve another copy
We have requested the book for you!
Your request is successful and it will be processed during the Library working hours. Please check the status of your request in My Requests.
Oops! Something went wrong.
Looks like we were not able to place your request. Kindly try again later.
Journal Article
Clinical symptoms and associated vascular imaging findings in Takayasu’s arteritis compared to giant cell arteritis
2020
Overview
ObjectiveTo compare the presence of head, neck and upper extremity symptoms in patients with Takayasu’s (TAK) and giant cell arteritis (GCA) and their association with vascular inflammation assessed by 18F-fluorodeoxyglucose positron emission tomography (FDG-PET) or arterial damage assessed by magnetic resonance angiography (MRA).MethodsPatients with TAK and GCA underwent clinical and imaging assessments within 24 hours, blinded to each other. Vascular inflammation was defined as arterial FDG-PET uptake greater than liver by visual assessment. Arterial damage was defined as stenosis, occlusion, or aneurysm by MRA. Clinically reported symptoms were compared with corresponding imaging findings using generalised mixed model regression. Cranial symptoms were studied in association with burden of arterial disease in the neck using ordinal regression.ResultsParticipants with TAK (n=56) and GCA (n=54) contributed data from 270 visits. Carotidynia was reported only in patients with TAK (21%) and was associated with vascular inflammation (p<0.01) but not damage (p=0.33) in the corresponding carotid artery. Posterior headache was reported in TAK (16%) and GCA (20%) but was only associated with corresponding vertebral artery inflammation and damage in GCA (p<0.01). Arm claudication was associated with subclavian artery damage (p<0.01) and inflammation (p=0.04) in TAK and with damage in GCA (p<0.01). Patients with an increased burden of damaged neck arteries were more likely to experience positional lightheadedness (p<0.01) or a major central nervous system event (p=0.01).ConclusionThe distribution of symptoms and association with imaging abnormalities differs in patients with TAK and GCA. These findings may help clinicians predict associated FDG-PET and MRA findings based on a specific clinical symptom.Clinical trial registration number NCT02257866.
Publisher
BMJ Publishing Group Ltd and European League Against Rheumatism,Elsevier Limited
Subject
/ Aged
/ Carotid Arteries - diagnostic imaging
/ Carotid Artery Diseases - diagnostic imaging
/ Carotid Artery Diseases - etiology
/ Female
/ Giant Cell Arteritis - complications
/ Giant Cell Arteritis - diagnostic imaging
/ Headache
/ Headache - diagnostic imaging
/ Humans
/ Intermittent Claudication - diagnostic imaging
/ Intermittent Claudication - etiology
/ Magnetic Resonance Angiography - methods
/ Male
/ Neck
/ Neck Pain - diagnostic imaging
/ Patients
/ Positron emission tomography
/ Positron-Emission Tomography - methods
/ Stenosis
/ Studies
/ Symptom Assessment - methods
/ Takayasu Arteritis - complications
