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Thirty-day postoperative mortality after colorectal cancer surgery in England
by
Forman, David
, Quirke, Philip
, Finan, Paul J
, Coleman, Michel P
, Morris, Eva J A
, Rachet, Bernard
, Thomas, James D
, Taylor, Elizabeth F
in
Adult
/ Age Distribution
/ Aged
/ Aged, 80 and over
/ Biological and medical sciences
/ Cancer
/ Cancer surgery
/ Colon
/ Colorectal cancer
/ Colorectal carcinoma
/ Colorectal Neoplasms - mortality
/ Colorectal Neoplasms - pathology
/ Colorectal Neoplasms - surgery
/ Comorbidity
/ Emergencies
/ England - epidemiology
/ Epidemiologic Methods
/ Female
/ Gastroenterology. Liver. Pancreas. Abdomen
/ Hospitals
/ Humans
/ Male
/ Medical prognosis
/ Medical sciences
/ Middle Aged
/ Mortality
/ Neoplasm Staging
/ Patients
/ Population studies
/ Sex Distribution
/ Socioeconomic Factors
/ State Medicine - statistics & numerical data
/ Stomach. Duodenum. Small intestine. Colon. Rectum. Anus
/ Surgery
/ Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases
/ Surgery of the digestive system
/ Surgical outcomes
/ surgical resection
/ Treatment Outcome
/ Trusts
/ Tumors
/ Variation
2011
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Thirty-day postoperative mortality after colorectal cancer surgery in England
by
Forman, David
, Quirke, Philip
, Finan, Paul J
, Coleman, Michel P
, Morris, Eva J A
, Rachet, Bernard
, Thomas, James D
, Taylor, Elizabeth F
in
Adult
/ Age Distribution
/ Aged
/ Aged, 80 and over
/ Biological and medical sciences
/ Cancer
/ Cancer surgery
/ Colon
/ Colorectal cancer
/ Colorectal carcinoma
/ Colorectal Neoplasms - mortality
/ Colorectal Neoplasms - pathology
/ Colorectal Neoplasms - surgery
/ Comorbidity
/ Emergencies
/ England - epidemiology
/ Epidemiologic Methods
/ Female
/ Gastroenterology. Liver. Pancreas. Abdomen
/ Hospitals
/ Humans
/ Male
/ Medical prognosis
/ Medical sciences
/ Middle Aged
/ Mortality
/ Neoplasm Staging
/ Patients
/ Population studies
/ Sex Distribution
/ Socioeconomic Factors
/ State Medicine - statistics & numerical data
/ Stomach. Duodenum. Small intestine. Colon. Rectum. Anus
/ Surgery
/ Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases
/ Surgery of the digestive system
/ Surgical outcomes
/ surgical resection
/ Treatment Outcome
/ Trusts
/ Tumors
/ Variation
2011
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Thirty-day postoperative mortality after colorectal cancer surgery in England
by
Forman, David
, Quirke, Philip
, Finan, Paul J
, Coleman, Michel P
, Morris, Eva J A
, Rachet, Bernard
, Thomas, James D
, Taylor, Elizabeth F
in
Adult
/ Age Distribution
/ Aged
/ Aged, 80 and over
/ Biological and medical sciences
/ Cancer
/ Cancer surgery
/ Colon
/ Colorectal cancer
/ Colorectal carcinoma
/ Colorectal Neoplasms - mortality
/ Colorectal Neoplasms - pathology
/ Colorectal Neoplasms - surgery
/ Comorbidity
/ Emergencies
/ England - epidemiology
/ Epidemiologic Methods
/ Female
/ Gastroenterology. Liver. Pancreas. Abdomen
/ Hospitals
/ Humans
/ Male
/ Medical prognosis
/ Medical sciences
/ Middle Aged
/ Mortality
/ Neoplasm Staging
/ Patients
/ Population studies
/ Sex Distribution
/ Socioeconomic Factors
/ State Medicine - statistics & numerical data
/ Stomach. Duodenum. Small intestine. Colon. Rectum. Anus
/ Surgery
/ Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases
/ Surgery of the digestive system
/ Surgical outcomes
/ surgical resection
/ Treatment Outcome
/ Trusts
/ Tumors
/ Variation
2011
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Thirty-day postoperative mortality after colorectal cancer surgery in England
Journal Article
Thirty-day postoperative mortality after colorectal cancer surgery in England
2011
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Overview
ObjectivesTo assess the variation in risk-adjusted 30-day postoperative mortality for patients with colorectal cancer between hospital trusts within the English NHS.DesignRetrospective cross-sectional population-based study of data extracted from the National Cancer Data Repository.SettingAll providers of major colorectal cancer surgery within the English NHS.ParticipantsAll 160 920 individuals who underwent major resection for colorectal cancer diagnosed between 1998 and 2006 in the English NHS.Main outcome measuresNational patterns of 30-day postoperative mortality were examined and logistic binary regression was used to study factors associated with death within 30 days of surgery. Funnel plots were used to show variation between trusts in risk-adjusted mortality.ResultsOverall 30-day mortality was 6.7% but decreased over time from 6.8% in 1998 to 5.8% in 2006. The largest reduction in mortality was seen in 2005 and 2006. Postoperative mortality increased with age (15.0% (95% CI 14.1% to 15.9%) for those aged >80 years), comorbidity (24.2% (95% CI 22.0% to 26.5%) for those with a Charlson comorbidity score ≥3), stage of disease (9.9% (95% CI 9.3% to 10.6%) for patients with Dukes' D disease), socioeconomic deprivation (7.8% (95% CI 7.2% to 8.4%) for residents of the most deprived quintile) and operative urgency (14.9% (95% CI 14.2% to 15.7%) for patients undergoing emergency resection). Risk-adjusted control charts showed that one trust had consistently significantly better outcomes and three had significantly worse outcomes than the population mean.ConclusionsSignificant variation in 30-day postoperative mortality following major colorectal cancer surgery existed between NHS hospitals in England throughout the period 1998–2006. Understanding the underlying causes of this variation between surgical providers will make it possible to identify and spread best practice, improve outcomes and, ultimately, reduce 30-day postoperative mortality following colorectal cancer surgery.
Publisher
BMJ Publishing Group Ltd and British Society of Gastroenterology,BMJ Publishing Group,BMJ Publishing Group LTD
Subject
/ Aged
/ Biological and medical sciences
/ Cancer
/ Colon
/ Colorectal Neoplasms - mortality
/ Colorectal Neoplasms - pathology
/ Colorectal Neoplasms - surgery
/ Female
/ Gastroenterology. Liver. Pancreas. Abdomen
/ Humans
/ Male
/ Patients
/ State Medicine - statistics & numerical data
/ Stomach. Duodenum. Small intestine. Colon. Rectum. Anus
/ Surgery
/ Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases
/ Surgery of the digestive system
/ Trusts
/ Tumors
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