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The efficacy of 5% topical tea tree oil gel in mild to moderate acne vulgaris: A randomized, double-blind placebo-controlled study
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The efficacy of 5% topical tea tree oil gel in mild to moderate acne vulgaris: A randomized, double-blind placebo-controlled study
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The efficacy of 5% topical tea tree oil gel in mild to moderate acne vulgaris: A randomized, double-blind placebo-controlled study
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Journal Article
The efficacy of 5% topical tea tree oil gel in mild to moderate acne vulgaris: A randomized, double-blind placebo-controlled study
2007
Overview
Background: Finding an effective treatment for acne that is well
tolerated by the patients is a challenge. One study has suggested the
efficacy of tea tree oil in treatment of the acne vulgaris. Aim: To
determine the efficacy of tea tree oil in mild to moderate acne
vulgaris. Methods: This was a randomized double-blind clinical trial
performed in 60 patients with mild to moderate acne vulgaris. They were
randomly divided into two groups and were treated with tea tree oil gel
(n=30) or placebo (n=30). They were followed every 15 days for a period
of 45 days. Response to treatment was evaluated by the total acne
lesions counting (TLC) and acne severity index (ASI). The data was
analyzed statistically using t-test and by SPSS program. Results:
There were no significant differences regarding demographic
characteristics between the two groups. There was a significant
difference between tea tree oil gel and placebo in the improvement of
the TLC and also regarding improvement of the ASI. In terms of TLC and
ASI, tea tree oil gel was 3.55 times and 5.75 times more effective than
placebo respectively. Side-effects with both groups were relatively
similar and tolerable. Conclusion: Topical 5% tea tree oil is an
effective treatment for mild to moderate acne vulgaris.
Publisher
Medknow Publications on behalf of The Indian Association of Dermatologists, Venereologists and Leprologists (IADVL),Indian Association of Dermatologists, Venereologists and Leprologists,Medknow Publications and Media Pvt. Ltd,Scientific Scholar
Subject
/ Acne Vulgaris - drug therapy
/ Acne vulgaris, Tea tree oil gel, Topical treatment
/ Adult
/ Anti-Infective Agents, Local - administration & dosage
/ Anti-Infective Agents, Local - adverse effects
/ Anti-Infective Agents, Local - therapeutic use
/ Biological and medical sciences
/ Female
/ Gels
/ Humans
/ Male
/ Skin involvement in other diseases. Miscellaneous. General aspects
/ Tea Tree Oil - administration & dosage
/ Tea Tree Oil - adverse effects
