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IDDF2024-ABS-0354 Impact of ethnicity and urbanization on the diversity of the gut microbiota in Southwest China
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IDDF2024-ABS-0354 Impact of ethnicity and urbanization on the diversity of the gut microbiota in Southwest China
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Journal Article
IDDF2024-ABS-0354 Impact of ethnicity and urbanization on the diversity of the gut microbiota in Southwest China
2024
Overview
BackgroundThe gut microbiota is known to have substantial impacts on human health. Although urbanization has been documented to modify the composition of the gut microbiota, limited attention has been given to the highly diverse Chinese populations.MethodsWe collected stool and saliva samples from six representative ethnic groups within the Yunnan province, with individuals of each ethnicity living in remote villages with traditional lifestyles and in the provincial capital, Kunming. Through metagenomic sequencing, de novo assembling, and subsequent analyses, marked diversity and differences in the gut microbiota among these populations were unveiled, with associations to genetic factors and lifestyles.ResultsOur findings reveal substantial variations in gut microbiota among different ethnic groups, and demonstrate that the effects of urbanization on gut microbiota differ across ethnicities.ConclusionsThis highlights the complexity of the relationship between socioeconomic factors and the gut microbiota, and the limitations of generalizing findings from a limited number of communities.
Publisher
BMJ Publishing Group Ltd and British Society of Gastroenterology,BMJ Publishing Group LTD
