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Genome sequence of the bioplastic-producing “Knallgas” bacterium Ralstonia eutropha H16

by Cramm, Rainer , Schwartz, Edward , Reinecke, Frank , Liesegang, Heiko , Ewering, Christian , Pötter, Markus , Kusian, Bernhard , Steinbüchel, Alexander , Friedrich, Bärbel , Eitinger, Thomas , Voß, Ingo , Gottschalk, Gerhard , Pohlmann, Anne , Bowien, Botho , Strittmatter, Axel , Fricke, Wolfgang Florian

in Aerobiosis / Agriculture / Anaerobiosis / Bacteria / Bacterial Toxins - genetics / Bacterial Toxins - metabolism / Biodegradable materials / Biodegradation / Bioinformatics / Biological and medical sciences / Biological Transport / Biology of microorganisms of confirmed or potential industrial interest / Biomedical and Life Sciences / Biomedical Engineering/Biotechnology / Biomedicine / Bioplastics / Biotechnology / Carbon - metabolism / Carbon dioxide / Chromosomes / Chromosomes, Bacterial / Cupriavidus necator - genetics / Cupriavidus necator - metabolism / Fundamental and applied biological sciences. Psychology / Genetics / Genome, Bacterial / Genomics / Hydroxybutyrates - metabolism / Life Sciences / Mission oriented research / Molecular Sequence Data / Plastics / Polyesters / Polyesters - metabolism / Ralstonia eutropha

2006

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Genome sequence of the bioplastic-producing “Knallgas” bacterium Ralstonia eutropha H16

2006

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Genome sequence of the bioplastic-producing “Knallgas” bacterium Ralstonia eutropha H16

2006

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Journal Article

Genome sequence of the bioplastic-producing “Knallgas” bacterium Ralstonia eutropha H16

Cramm, Rainer,

Schwartz, Edward,

Reinecke, Frank,

Liesegang, Heiko,

Ewering, Christian,

Pötter, Markus,

Kusian, Bernhard,

Steinbüchel, Alexander,

Friedrich, Bärbel,

Eitinger, Thomas,

Voß, Ingo,

Gottschalk, Gerhard,

Pohlmann, Anne,

Bowien, Botho,

Strittmatter, Axel,

Fricke, Wolfgang Florian

2006

Overview

The H 2 -oxidizing lithoautotrophic bacterium Ralstonia eutropha H16 is a metabolically versatile organism capable of subsisting, in the absence of organic growth substrates, on H 2 and CO 2 as its sole sources of energy and carbon. R. eutropha H16 first attracted biotechnological interest nearly 50 years ago with the realization that the organism's ability to produce and store large amounts of poly[ R -(–)-3-hydroxybutyrate] and other polyesters could be harnessed to make biodegradable plastics. Here we report the complete genome sequence of the two chromosomes of R. eutropha H16. Together, chromosome 1 (4,052,032 base pairs (bp)) and chromosome 2 (2,912,490 bp) encode 6,116 putative genes. Analysis of the genome sequence offers the genetic basis for exploiting the biotechnological potential of this organism and provides insights into its remarkable metabolic versatility.

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Publisher

Nature Publishing Group US,Nature,Nature Publishing Group

Subject

/ Bacterial Toxins - genetics

/ Bacterial Toxins - metabolism

/ Biodegradable materials