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Development of Inorganic Iodine Quantitative Determination in the kelp Thalli (Laminariae thalli) by Spectrophotometric Method for Solving Pharmacognostic Issues
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Development of Inorganic Iodine Quantitative Determination in the kelp Thalli (Laminariae thalli) by Spectrophotometric Method for Solving Pharmacognostic Issues
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Development of Inorganic Iodine Quantitative Determination in the kelp Thalli (Laminariae thalli) by Spectrophotometric Method for Solving Pharmacognostic Issues
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Journal Article
Development of Inorganic Iodine Quantitative Determination in the kelp Thalli (Laminariae thalli) by Spectrophotometric Method for Solving Pharmacognostic Issues
2024
Overview
The work presents a new spectrophotometric method of determining iodine inorganic forms in the kelp thalli (Laminariae thalli). A glycerin-stabilized starch solution was used as a coloring reagent. The developed method is characterized by ease of implementation, high selectivity and sensitivity (at the ng/ml level) as opposed to available methods in the literature. High stability of the analytical signal, linearity in the range from 60 to 720 ng/ml, accuracy, repeatability, and intermediate precision were established by research of metrological characteristics. The detection limit and quantification limit in solutions obtained after sample preparation were 20 and 60ng/ml. The proposed methodology may be recommended for research as well as in regulatory documentation for crude herbal drug (CHD).
