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ACTN3/ EXON-19 GENE POLYMORPHISM AND RELATIONSHIP WITH LOCAL HORSES PERFORMANCE IN IRAQ
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ACTN3/ EXON-19 GENE POLYMORPHISM AND RELATIONSHIP WITH LOCAL HORSES PERFORMANCE IN IRAQ
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Journal Article
ACTN3/ EXON-19 GENE POLYMORPHISM AND RELATIONSHIP WITH LOCAL HORSES PERFORMANCE IN IRAQ
2025
Overview
This study was conducted to investigate the polymorphism of ACTN3/EXON-19 gene and their relationship the performance of local horses in Iraq. This study was carried out at the Iraqi Equestrian Club (15 km west from Baghdad city center) period during d from 1 February to 30 December 2022, to investigate the gene polymorphism of ACTN3 region EXON-19 and their relationship with performance of local horses in Iraq. Were found three variants (3 SNPs) in the ACTN3 gene - exon 19 and in different locations, namely rs1148960207, whose genotypes were CC, CT, and TT, as their distribution rates were significantly different (P≤0.05). The ratios of heterogeneity rs1144413495 with genotypes CC, TC, and TT were 34.21, 60.53, and 5.26% that differ significantly at (P≤0.01), with an allelic frequency of 0.64 and 0.36 for the two alleles C and T, respectively. The variant rs1148960207 had a significant (P≤0.05) effect on post-exercise breathing depth, speed rate and body length. Moreover a highly significant (P≤0.01) effect on heart girth and forefoot height for local horses. In conclusion ACTN3 gene has a distinct role in some physiological traits like the number and depth of respiration after exercise, rate of speed, and some body measurements, like body length, heart girth, and frontal height.
Publisher
Jami'at Baghdad,Baghdad University
