Asset Details
Do you wish to reserve the book?
Antidiabetic effects of fractions of methanol extract of Solanum macrocarpon Linn. On streptozotocin – induced diabetic male Wistar rats
Hey, we have placed the reservation for you!
By the way, why not check out events that you can attend while you pick your title.
Oops! Something went wrong.
Looks like we were not able to place the reservation. Kindly try again later.
Are you sure you want to remove the book from the shelf?
Antidiabetic effects of fractions of methanol extract of Solanum macrocarpon Linn. On streptozotocin – induced diabetic male Wistar rats
Do you wish to request the book?
Antidiabetic effects of fractions of methanol extract of Solanum macrocarpon Linn. On streptozotocin – induced diabetic male Wistar rats
Please be aware that the book you have requested cannot be checked out. If you would like to checkout this book, you can reserve another copy
We have requested the book for you!
Your request is successful and it will be processed during the Library working hours. Please check the status of your request in My Requests.
Oops! Something went wrong.
Looks like we were not able to place your request. Kindly try again later.
Journal Article
Antidiabetic effects of fractions of methanol extract of Solanum macrocarpon Linn. On streptozotocin – induced diabetic male Wistar rats
2024
Overview
Solanum macrocarpon Linn. (SM) is a well eaten vegetable and prominent for treatment of diseases in folk medicine. This study evaluated the antidiabetic potentials of fractions of methanol extract of Solanum macrocarpon in streptozotocin – induced diabetic male Wistar rats.Diabetes mellitus (DM) was induced in Wistar rats by single (i.p.) dose of 50 mg/kg streptozotocin (STZ) and diabetic rats were administered the extract(s) once daily for four weeks. The effect was determined on body weight (BW), blood glucose concentration (BGC), oral glucose tolerance test (OGGT), heamatological indices and lipid profiles. Also, the pancreatic level of oxidative stress and histopathology were determined. Treatment with extracts significantly decreased the elevated BGC, and improved OGTT and BW of diabetic rats. Heamatological indices, lipid profiles and pancreatic level of oxidative stress were augmented to near normalcy in diabetic rats administered the extract. Histopathology slides showed improvement in structural integrity of diabetic rats upon treatment with the extracts. The findings of this study have clearly shown that Solanum macrocarpon possess antidiabetic ability and could be used in the management of diabetes mellitus.
