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Pseudo-outbreak of Mycobacterium gordonae Following the Opening of a Newly Constructed Hospital at a Chicago Medical Center
by
Hayden, Mary K.
, Lavin, Mary A.
, Trenholme, Gordon M.
, Schmitt, Barbara A.
, Weinstein, Robert A.
, Cheerala, Jyothirmai
, L. Scorza, Mary
, Segreti, John
, Muthiah, Chethra
, Welbel, Sharon F.
, Prabaker, Kavitha
, Beavis, Kathleen G.
in
Bronchoalveolar Lavage Fluid - microbiology
/ Carrier State - epidemiology
/ Carrier State - microbiology
/ Chicago - epidemiology
/ Colony Count, Microbial
/ Contaminants
/ Disease Outbreaks
/ Drinking water
/ Drinking Water - microbiology
/ Epidemics
/ Flooring
/ Gastric Juice - microbiology
/ Hospitals
/ Hospitals, University
/ Humans
/ Infections
/ Laboratories
/ Microscopy
/ Mycobacterium Infections, Nontuberculous - epidemiology
/ Mycobacterium Infections, Nontuberculous - microbiology
/ Nontuberculous Mycobacteria
/ Outbreaks
/ Patients
/ Pollution control
/ Sputum - microbiology
/ Tuberculosis
/ Water analysis
/ Water Microbiology
/ Water pollution
/ Water sampling
/ Water supply
/ Waterborne diseases
2015
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Pseudo-outbreak of Mycobacterium gordonae Following the Opening of a Newly Constructed Hospital at a Chicago Medical Center
by
Hayden, Mary K.
, Lavin, Mary A.
, Trenholme, Gordon M.
, Schmitt, Barbara A.
, Weinstein, Robert A.
, Cheerala, Jyothirmai
, L. Scorza, Mary
, Segreti, John
, Muthiah, Chethra
, Welbel, Sharon F.
, Prabaker, Kavitha
, Beavis, Kathleen G.
in
Bronchoalveolar Lavage Fluid - microbiology
/ Carrier State - epidemiology
/ Carrier State - microbiology
/ Chicago - epidemiology
/ Colony Count, Microbial
/ Contaminants
/ Disease Outbreaks
/ Drinking water
/ Drinking Water - microbiology
/ Epidemics
/ Flooring
/ Gastric Juice - microbiology
/ Hospitals
/ Hospitals, University
/ Humans
/ Infections
/ Laboratories
/ Microscopy
/ Mycobacterium Infections, Nontuberculous - epidemiology
/ Mycobacterium Infections, Nontuberculous - microbiology
/ Nontuberculous Mycobacteria
/ Outbreaks
/ Patients
/ Pollution control
/ Sputum - microbiology
/ Tuberculosis
/ Water analysis
/ Water Microbiology
/ Water pollution
/ Water sampling
/ Water supply
/ Waterborne diseases
2015
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Pseudo-outbreak of Mycobacterium gordonae Following the Opening of a Newly Constructed Hospital at a Chicago Medical Center
by
Hayden, Mary K.
, Lavin, Mary A.
, Trenholme, Gordon M.
, Schmitt, Barbara A.
, Weinstein, Robert A.
, Cheerala, Jyothirmai
, L. Scorza, Mary
, Segreti, John
, Muthiah, Chethra
, Welbel, Sharon F.
, Prabaker, Kavitha
, Beavis, Kathleen G.
in
Bronchoalveolar Lavage Fluid - microbiology
/ Carrier State - epidemiology
/ Carrier State - microbiology
/ Chicago - epidemiology
/ Colony Count, Microbial
/ Contaminants
/ Disease Outbreaks
/ Drinking water
/ Drinking Water - microbiology
/ Epidemics
/ Flooring
/ Gastric Juice - microbiology
/ Hospitals
/ Hospitals, University
/ Humans
/ Infections
/ Laboratories
/ Microscopy
/ Mycobacterium Infections, Nontuberculous - epidemiology
/ Mycobacterium Infections, Nontuberculous - microbiology
/ Nontuberculous Mycobacteria
/ Outbreaks
/ Patients
/ Pollution control
/ Sputum - microbiology
/ Tuberculosis
/ Water analysis
/ Water Microbiology
/ Water pollution
/ Water sampling
/ Water supply
/ Waterborne diseases
2015
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Pseudo-outbreak of Mycobacterium gordonae Following the Opening of a Newly Constructed Hospital at a Chicago Medical Center
Journal Article
Pseudo-outbreak of Mycobacterium gordonae Following the Opening of a Newly Constructed Hospital at a Chicago Medical Center
2015
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Overview
OBJECTIVE To identify the source of a pseudo-outbreak of Mycobacterium gordonae DESIGN Outbreak investigation. SETTING University Hospital in Chicago, Ilinois. PATIENTS Hospital patients with M. gordonae-positive clinical cultures. METHODS An increase in isolation of M. gordonae from clinical cultures was noted immediately following the opening of a newly constructed hospital in January 2012. We reviewed medical records of patients with M. gordonae-positive cultures collected between January and December 2012 and cultured potable water specimens in new and old hospitals quantitatively for mycobacteria. RESULTS Of 30 patients with M. gordonae-positive clinical cultures, 25 (83.3%) were housed in the new hospital; of 35 positive specimens (sputum, bronchoalveolar lavage, gastric aspirate), 32 (91.4%) had potential for water contamination. M. gordonae was more common in water collected from the new vs. the old hospital [147 of 157 (93.6%) vs. 91 of 113 (80.5%), P=.001]. Median concentration of M. gordonae was higher in the samples from the new vs. the old hospital (208 vs. 48 colony-forming units (CFU)/mL; P<.001). Prevalence and concentration of M. gordonae were lower in water samples from ice and water dispensers [13 of 28 (46.4%) and 0 CFU/mL] compared with water samples from patient rooms and common areas [225 of 242 (93%) and 146 CFU/mL, P<.001]. CONCLUSIONS M. gordonae was common in potable water. The pseudo-outbreak of M. gordonae was likely due to increased concentrations of M. gordonae in the potable water supply of the new hospital. A silver ion-impregnated 0.5-μm filter may have been responsible for lower concentrations of M. gordonae identified in ice/water dispenser samples. Hospitals should anticipate that construction activities may amplify the presence of waterborne nontuberculous mycobacterial contaminants.
Publisher
Cambridge University Press
Subject
Bronchoalveolar Lavage Fluid - microbiology
/ Carrier State - epidemiology
/ Carrier State - microbiology
/ Drinking Water - microbiology
/ Flooring
/ Gastric Juice - microbiology
/ Humans
/ Mycobacterium Infections, Nontuberculous - epidemiology
/ Mycobacterium Infections, Nontuberculous - microbiology
/ Patients
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