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There is an exception to every rule—T2-FLAIR mismatch sign in gliomas
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Journal Article
There is an exception to every rule—T2-FLAIR mismatch sign in gliomas
2019
Overview
The T2-FLAIR mismatch sign, in which a low-grade glioma is hyperintense on T2-weighted MR and centrally hypointense on T2-weighted FLAIR MR, has been reported as 100% specific for
IDH
-mutant astrocytomas in several series. We report several cases of “false positive” T2-FLAIR mismatch sign occurring outside the context of
IDH
-mutant astrocytomas, predominantly in children or young adults with pediatric-type gliomas. These results suggest caution in the interpretation of the T2-FLAIR mismatch sign in the pediatric glioma population.
