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Astroglial clean-up of satiety synapses
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Journal Article
Astroglial clean-up of satiety synapses
2022
Overview
Until now, the BDNF–TrkB signalling pathway was thought to be exclusively regulated by neurons. Ameroso et al. show that astrocytic TrkB.T1 is a critical substrate of BDNF in the regulation of energy balance and that its defective signalling in hypothalamic circuits leads to obesity.
Publisher
Nature Publishing Group UK,Nature Publishing Group
Subject
