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New dimensions for fluorescence-based barcoding in complex mixtures
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New dimensions for fluorescence-based barcoding in complex mixtures
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Journal Article
New dimensions for fluorescence-based barcoding in complex mixtures
2024
Overview
Combining single-molecule Förster resonance energy transfer (FRET) and fluorescence lifetime information inside an anti-Brownian electrokinetic (ABEL) trap makes it possible to distinguish dozens of biomolecules in a sample mixture. This method enables extensive barcoding of biomolecules with a minimal set of chemical components and opens up a path toward biomolecule quantification in complex mixtures.
Publisher
Nature Publishing Group UK,Nature Publishing Group
