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Mechanisms Protecting Acinetobacter baumannii against Multiple Stresses Triggered by the Host Immune Response, Antibiotics and Outside-Host Environment
by
Łupkowska, Adrianna
, Kuczyńska-Wiśnik, Dorota
, Furmanek-Blaszk, Beata
, Laskowska, Ewa
, Stojowska-Swędrzyńska, Karolina
, Monem, Soroosh
in
Acinetobacter baumannii - genetics
/ Acinetobacter baumannii - pathogenicity
/ Acinetobacter Infections - genetics
/ Acinetobacter Infections - immunology
/ Acinetobacter Infections - microbiology
/ Anti-Bacterial Agents - therapeutic use
/ Antibiotics
/ Bacteria
/ Bacterial infections
/ Biofilms
/ Biofilms - growth & development
/ Drug resistance
/ Drug Resistance, Multiple, Bacterial - genetics
/ Gram-negative bacteria
/ Host-Pathogen Interactions - genetics
/ Humans
/ Immune response
/ Immune system
/ Immunity - genetics
/ Infections
/ Multidrug resistant organisms
/ Neutrophils
/ Pathogens
/ Peptides
/ Review
/ Signal transduction
/ Tumor necrosis factor-TNF
/ Virulence
/ Virulence - genetics
2020
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Mechanisms Protecting Acinetobacter baumannii against Multiple Stresses Triggered by the Host Immune Response, Antibiotics and Outside-Host Environment
by
Łupkowska, Adrianna
, Kuczyńska-Wiśnik, Dorota
, Furmanek-Blaszk, Beata
, Laskowska, Ewa
, Stojowska-Swędrzyńska, Karolina
, Monem, Soroosh
in
Acinetobacter baumannii - genetics
/ Acinetobacter baumannii - pathogenicity
/ Acinetobacter Infections - genetics
/ Acinetobacter Infections - immunology
/ Acinetobacter Infections - microbiology
/ Anti-Bacterial Agents - therapeutic use
/ Antibiotics
/ Bacteria
/ Bacterial infections
/ Biofilms
/ Biofilms - growth & development
/ Drug resistance
/ Drug Resistance, Multiple, Bacterial - genetics
/ Gram-negative bacteria
/ Host-Pathogen Interactions - genetics
/ Humans
/ Immune response
/ Immune system
/ Immunity - genetics
/ Infections
/ Multidrug resistant organisms
/ Neutrophils
/ Pathogens
/ Peptides
/ Review
/ Signal transduction
/ Tumor necrosis factor-TNF
/ Virulence
/ Virulence - genetics
2020
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Mechanisms Protecting Acinetobacter baumannii against Multiple Stresses Triggered by the Host Immune Response, Antibiotics and Outside-Host Environment
by
Łupkowska, Adrianna
, Kuczyńska-Wiśnik, Dorota
, Furmanek-Blaszk, Beata
, Laskowska, Ewa
, Stojowska-Swędrzyńska, Karolina
, Monem, Soroosh
in
Acinetobacter baumannii - genetics
/ Acinetobacter baumannii - pathogenicity
/ Acinetobacter Infections - genetics
/ Acinetobacter Infections - immunology
/ Acinetobacter Infections - microbiology
/ Anti-Bacterial Agents - therapeutic use
/ Antibiotics
/ Bacteria
/ Bacterial infections
/ Biofilms
/ Biofilms - growth & development
/ Drug resistance
/ Drug Resistance, Multiple, Bacterial - genetics
/ Gram-negative bacteria
/ Host-Pathogen Interactions - genetics
/ Humans
/ Immune response
/ Immune system
/ Immunity - genetics
/ Infections
/ Multidrug resistant organisms
/ Neutrophils
/ Pathogens
/ Peptides
/ Review
/ Signal transduction
/ Tumor necrosis factor-TNF
/ Virulence
/ Virulence - genetics
2020
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Mechanisms Protecting Acinetobacter baumannii against Multiple Stresses Triggered by the Host Immune Response, Antibiotics and Outside-Host Environment
Journal Article
Mechanisms Protecting Acinetobacter baumannii against Multiple Stresses Triggered by the Host Immune Response, Antibiotics and Outside-Host Environment
2020
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Overview
Acinetobacter baumannii is considered one of the most persistent pathogens responsible for nosocomial infections. Due to the emergence of multidrug resistant strains, as well as high morbidity and mortality caused by this pathogen, A. baumannii was placed on the World Health Organization (WHO) drug-resistant bacteria and antimicrobial resistance research priority list. This review summarizes current studies on mechanisms that protect A. baumannii against multiple stresses caused by the host immune response, outside host environment, and antibiotic treatment. We particularly focus on the ability of A. baumannii to survive long-term desiccation on abiotic surfaces and the population heterogeneity in A. baumannii biofilms. Insight into these protective mechanisms may provide clues for the development of new strategies to fight multidrug resistant strains of A. baumannii.
Publisher
MDPI AG,MDPI
Subject
Acinetobacter baumannii - genetics
/ Acinetobacter baumannii - pathogenicity
/ Acinetobacter Infections - genetics
/ Acinetobacter Infections - immunology
/ Acinetobacter Infections - microbiology
/ Anti-Bacterial Agents - therapeutic use
/ Bacteria
/ Biofilms
/ Biofilms - growth & development
/ Drug Resistance, Multiple, Bacterial - genetics
/ Host-Pathogen Interactions - genetics
/ Humans
/ Multidrug resistant organisms
/ Peptides
/ Review
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