Asset Details
Do you wish to reserve the book?
Association of Frailty and Frailty Trajectory with Risk for Respiratory Infectious Diseases
Hey, we have placed the reservation for you!
By the way, why not check out events that you can attend while you pick your title.
Oops! Something went wrong.
Looks like we were not able to place the reservation. Kindly try again later.
Are you sure you want to remove the book from the shelf?
Association of Frailty and Frailty Trajectory with Risk for Respiratory Infectious Diseases
Do you wish to request the book?
Association of Frailty and Frailty Trajectory with Risk for Respiratory Infectious Diseases
Please be aware that the book you have requested cannot be checked out. If you would like to checkout this book, you can reserve another copy
We have requested the book for you!
Your request is successful and it will be processed during the Library working hours. Please check the status of your request in My Requests.
Oops! Something went wrong.
Looks like we were not able to place your request. Kindly try again later.
Journal Article
Association of Frailty and Frailty Trajectory with Risk for Respiratory Infectious Diseases
2026
Overview
We explored the association between frailty and respiratory infectious diseases (RIDs) through a large cohort of 423,691 participants in the UK Biobank. Participants without baseline RIDs were assessed by physical frailty and frailty index. A total of 16,848 participants had repeated assessments. We divided participants into nonfrail, prefrail, and frail groups and categorized frailty changes as alleviation, maintenance, or aggravation. We estimated risk for RIDs, including influenza, pneumonia, and other acute lower respiratory infections. Compared with nonfrailty, prefrailty and frailty increased risk for RIDs 1.32-2.29 times. Each 0.1-point increase in frailty index per year raised risk for RIDs by 47%; each 1-point increase in physical frailty per year increased risk by 26%. Frailty worsening (e.g., aggravation of prefrailty) amplified risk by 2.31-4.16 times. Partial frailty improvement did not fully eliminate risk. Frailty is a modifiable, dynamic risk factor, underscoring the need for early frailty identification and intervention to reduce RIDs in high-risk populations.
Publisher
Centers for Disease Control and Prevention
Subject
