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Intussusception after Rotavirus Vaccination — Spontaneous Reports
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Journal Article
Intussusception after Rotavirus Vaccination — Spontaneous Reports
2011
Overview
To the Editor:
Patel et al. report an increased risk of intussusception after rotavirus vaccination.
1
We conducted a case-series analysis
2
of 151 spontaneous reports of intussusception worldwide after administration of the rotavirus vaccine RV1 (Rotarix, GlaxoSmithKline Biologicals). On the basis of a report citing the incidence of intussusception after administration of the rotavirus vaccine RotaShield (Wyeth Laboratories),
3
we tested for an increased risk of intussusception 3 to 7 days after administration of the first dose. Incidence ratios were calculated for the periods 0 through 2 days (with 0 indicating the day of vaccination), 3 through 7 days, and 8 through . . .
Publisher
Massachusetts Medical Society
Subject
