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Visceral Leishmaniasis Following A+AVD Treatment in a Patient with Classical Hodgkin’s Lymphoma: A Case Report and Review of the Literature
by
Santoni, Eleonora
, Bernardelli, Andrea
, Quaglia, Francesca Maria
, Visco, Carlo
, Banegas, Daniela Estefania
, Tagliavini, Erica
, Moioli, Alessia
in
Anemia
/ Antifungal agents
/ Antimitotic agents
/ Antineoplastic agents
/ Asymptomatic
/ Bone marrow
/ Cancer
/ Care and treatment
/ Case studies
/ Chemotherapy
/ Chronic illnesses
/ Communicable diseases
/ Complications and side effects
/ Development and progression
/ Dosage and administration
/ Erythema
/ Fever
/ Hematology
/ HIV
/ Hodgkin's disease
/ Human immunodeficiency virus
/ Immune system
/ Immunotherapy
/ Infections
/ Kala-azar
/ Leukemia
/ Literature reviews
/ Lymphatic diseases
/ Lymphoma
/ Medical imaging
/ Medical research
/ Medicine, Experimental
/ Monoclonal antibodies
/ Non-Hodgkin's lymphomas
/ Older people
/ Parasites
/ Parasitic diseases
/ Patients
/ Physiological aspects
/ Review
/ Risk factors
/ Spleen
/ Ultrasonic imaging
2024
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Visceral Leishmaniasis Following A+AVD Treatment in a Patient with Classical Hodgkin’s Lymphoma: A Case Report and Review of the Literature
by
Santoni, Eleonora
, Bernardelli, Andrea
, Quaglia, Francesca Maria
, Visco, Carlo
, Banegas, Daniela Estefania
, Tagliavini, Erica
, Moioli, Alessia
in
Anemia
/ Antifungal agents
/ Antimitotic agents
/ Antineoplastic agents
/ Asymptomatic
/ Bone marrow
/ Cancer
/ Care and treatment
/ Case studies
/ Chemotherapy
/ Chronic illnesses
/ Communicable diseases
/ Complications and side effects
/ Development and progression
/ Dosage and administration
/ Erythema
/ Fever
/ Hematology
/ HIV
/ Hodgkin's disease
/ Human immunodeficiency virus
/ Immune system
/ Immunotherapy
/ Infections
/ Kala-azar
/ Leukemia
/ Literature reviews
/ Lymphatic diseases
/ Lymphoma
/ Medical imaging
/ Medical research
/ Medicine, Experimental
/ Monoclonal antibodies
/ Non-Hodgkin's lymphomas
/ Older people
/ Parasites
/ Parasitic diseases
/ Patients
/ Physiological aspects
/ Review
/ Risk factors
/ Spleen
/ Ultrasonic imaging
2024
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Visceral Leishmaniasis Following A+AVD Treatment in a Patient with Classical Hodgkin’s Lymphoma: A Case Report and Review of the Literature
by
Santoni, Eleonora
, Bernardelli, Andrea
, Quaglia, Francesca Maria
, Visco, Carlo
, Banegas, Daniela Estefania
, Tagliavini, Erica
, Moioli, Alessia
in
Anemia
/ Antifungal agents
/ Antimitotic agents
/ Antineoplastic agents
/ Asymptomatic
/ Bone marrow
/ Cancer
/ Care and treatment
/ Case studies
/ Chemotherapy
/ Chronic illnesses
/ Communicable diseases
/ Complications and side effects
/ Development and progression
/ Dosage and administration
/ Erythema
/ Fever
/ Hematology
/ HIV
/ Hodgkin's disease
/ Human immunodeficiency virus
/ Immune system
/ Immunotherapy
/ Infections
/ Kala-azar
/ Leukemia
/ Literature reviews
/ Lymphatic diseases
/ Lymphoma
/ Medical imaging
/ Medical research
/ Medicine, Experimental
/ Monoclonal antibodies
/ Non-Hodgkin's lymphomas
/ Older people
/ Parasites
/ Parasitic diseases
/ Patients
/ Physiological aspects
/ Review
/ Risk factors
/ Spleen
/ Ultrasonic imaging
2024
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Visceral Leishmaniasis Following A+AVD Treatment in a Patient with Classical Hodgkin’s Lymphoma: A Case Report and Review of the Literature
Journal Article
Visceral Leishmaniasis Following A+AVD Treatment in a Patient with Classical Hodgkin’s Lymphoma: A Case Report and Review of the Literature
2024
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Overview
We present the case of a 43-year-old Caucasian man who developed visceral leishmaniasis (VL) following treatment with a combination of brentuximab vedotin and doxorubicin, vinblastine, and dacarbazine (A+AVD) for advanced-stage classical Hodgkin’s lymphoma (cHL). The patient initially showed a favorable response to the treatment, but shortly after completing six cycles, he experienced recurrent fever, splenomegaly, and severe anemia. Extensive infectious disease evaluations led to a diagnosis of VL, confirmed by PCR testing. The patient was treated with amphotericin B, resulting in full clinical recovery. In addition to presenting this rare case, we conducted a full review of the literature on VL in the context of hematological disorders, including non-Hodgkin’s lymphoma, splenic marginal zone lymphoma, and other lymphoproliferative diseases. This review highlights the increasing prevalence of VL in immunocompromised individuals, particularly those undergoing treatments like chemotherapy or immunotherapy, and underscores the importance of considering VL in differential diagnoses when such patients present with persistent fever and splenomegaly.
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