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Next-Generation Multitarget Stool DNA Test for Colorectal Cancer Screening

by Statz, Sandi , Berkelhammer, Charles , Garces, Jorge , Olson, Marilyn C. , Imperiale, Thomas F. , Gagrat, Zubin D. , Kisiel, John B. , Limburg, Paul J. , Aguilar, Humberto , Brinberg, Don , Lavin, Philip T. , Porter, Kyle , Zella, Julia

in Adenoma / Adenoma - diagnosis / Adult / Asymptomatic Diseases / Cancer screening / Clinical Medicine / Clinical Medicine General / Colonoscopy / Colorectal cancer / Colorectal Neoplasms - diagnosis / Deoxyribonucleic acid / DNA / DNA - analysis / Early Detection of Cancer - methods / FDA approval / Feces / Feces - chemistry / Gastroenterology / Gastrointestinal Tract Cancer / Genetic testing / Genetics / Genetics General / Hematology / Hemoglobin / Humans / Immunochemistry - methods / Immunologic Tests - methods / Laboratories / Lesions / Medical screening / Oncology / Outpatient-Based Clinical Medicine / Paternity / Population / Precancerous Conditions - diagnosis / Prospective Studies / Sensitivity analysis / Sensitivity and Specificity

2024

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2024

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2024

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Journal Article

Next-Generation Multitarget Stool DNA Test for Colorectal Cancer Screening

Statz, Sandi,

Berkelhammer, Charles,

Garces, Jorge,

Olson, Marilyn C.,

Imperiale, Thomas F.,

Gagrat, Zubin D.,

Kisiel, John B.,

Limburg, Paul J.,

Aguilar, Humberto,

Brinberg, Don,

Lavin, Philip T.,

Porter, Kyle,

Zella, Julia

2024

Overview

In adults undergoing screening colonoscopy, a next-generation multitarget stool DNA test had higher sensitivity for colorectal cancer and advanced precancerous lesions than a fecal immunochemical test but lower specificity.

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Publisher

Massachusetts Medical Society

Subject

Adenoma

/ Adenoma - diagnosis

/ Adult

/ Asymptomatic Diseases

/ Cancer screening

/ Clinical Medicine

/ Clinical Medicine General