Asset Details
Do you wish to reserve the book?
Disease relative risk downscaling model to localize spatial epidemiologic indicators for mapping hand, foot, and mouth disease over China
Hey, we have placed the reservation for you!
By the way, why not check out events that you can attend while you pick your title.
Oops! Something went wrong.
Looks like we were not able to place the reservation. Kindly try again later.
Are you sure you want to remove the book from the shelf?
Disease relative risk downscaling model to localize spatial epidemiologic indicators for mapping hand, foot, and mouth disease over China
Do you wish to request the book?
Disease relative risk downscaling model to localize spatial epidemiologic indicators for mapping hand, foot, and mouth disease over China
Please be aware that the book you have requested cannot be checked out. If you would like to checkout this book, you can reserve another copy
We have requested the book for you!
Your request is successful and it will be processed during the Library working hours. Please check the status of your request in My Requests.
Oops! Something went wrong.
Looks like we were not able to place your request. Kindly try again later.
Journal Article
Disease relative risk downscaling model to localize spatial epidemiologic indicators for mapping hand, foot, and mouth disease over China
2019
Overview
Given the limitations of current approaches for disease relative risk mapping, it is necessary to develop a comprehensive mapping method not only to simultaneously downscale various epidemiologic indicators, but also to be suitable for different disease outcomes. We proposed a three-step progressive statistical method, named disease relative risk downscaling (DRRD) model, to localize different spatial epidemiologic relative risk indicators for disease mapping, and applied it to the real world hand, foot, and mouth disease (HFMD) occurrence data over Mainland China. First, to generate a spatially complete crude risk map for disease binary variable, we employed ordinary and spatial logistic regression models under Bayesian hierarchical modeling framework to estimate county-level HFMD occurrence probabilities. Cross-validation showed that spatial logistic regression (average prediction accuracy: 80.68%) outperformed ordinary logistic regression (69.75%), indicating the effectiveness of incorporating spatial autocorrelation effect in modeling. Second, for the sake of designing a suitable spatial case–control study, we took spatial stratified heterogeneity impact expressed as Chinese seven geographical divisions into consideration. Third, for generating different types of disease relative risk maps, we proposed local-scale formulas for calculating three spatial epidemiologic indicators, i.e., spatial odds ratio, spatial risk ratio, and spatial attributable risk. The immediate achievement of this study is constructing a series of national disease relative risk maps for China’s county-level HFMD interventions. The new DRRD model provides a more convenient and easily extended way for assessing local-scale relative risks in spatial and environmental epidemiology, as well as broader risk assessment sciences.
Publisher
Springer Nature B.V
