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ANCA-associated diffuse alveolar hemorrhage due to benzylthiouracil
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ANCA-associated diffuse alveolar hemorrhage due to benzylthiouracil
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Journal Article
ANCA-associated diffuse alveolar hemorrhage due to benzylthiouracil
2006
Overview
Benzylthiouracil has been recently observed to be associated with antineutrophil cytoplasmic antibody-positive vasculitis, resulting in crescentic glomerulonephritis. We report an 8-year-old girl treated with benzylthiouracil for Graves's disease who developed an ANCA-positive vasculitis with pulmonary hemorrhage. She responded to corticosteroids and discontinuation of benzylthiouracil. This represents the first pediatric case of benzylthiouracil-induced diffuse alveolar hemorrhage.
Publisher
Springer,Springer Nature B.V
Subject
Antibodies, Antineutrophil Cytoplasmic - immunology
/ Biological and medical sciences
/ Child
/ Female
/ Graves Disease - drug therapy
/ Hemorrhage - chemically induced
/ Humans
/ Lung Diseases - chemically induced
/ Thiouracil - adverse effects
/ Thiouracil - analogs & derivatives
/ Thiouracil - therapeutic use
