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Anti-CD19 CAR T Cells in CNS Diffuse Large-B-Cell Lymphoma
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Anti-CD19 CAR T Cells in CNS Diffuse Large-B-Cell Lymphoma
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Journal Article
Anti-CD19 CAR T Cells in CNS Diffuse Large-B-Cell Lymphoma
2017
Overview
In this case, a woman with refractory diffuse large-B-cell lymphoma had a CNS recurrence that responded completely to anti-CD19 CAR T-cell therapy. After biopsy of a subsequent skin recurrence, the lesions cleared in association with an expansion of the CAR T cells in the blood.
Publisher
Massachusetts Medical Society
Subject
/ Antineoplastic Agents - therapeutic use
/ Brain Neoplasms - diagnostic imaging
/ Brain Neoplasms - drug therapy
/ Female
/ Humans
/ Lymphoma, Large B-Cell, Diffuse - drug therapy
/ Lymphoma, Large B-Cell, Diffuse - therapy
/ Positron Emission Tomography Computed Tomography
