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The impact of adverse childhood experiences on age of diabetes diagnosis and associations with race and ethnicity
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The impact of adverse childhood experiences on age of diabetes diagnosis and associations with race and ethnicity
The impact of adverse childhood experiences on age of diabetes diagnosis and associations with race and ethnicity
Journal Article

The impact of adverse childhood experiences on age of diabetes diagnosis and associations with race and ethnicity

2026
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Overview
Previous research has linked the manifestation of multiple chronic diseases that are frequently due to health behaviors to adverse childhood experiences (ACEs). Despite this, the link between ACEs and the age of type 2 diabetes mellitus (T2DM) diagnosis is scarce. As such, our primary objective was to evaluate and describe the impact of ACEs on the age at diagnosis utilizing the data from the 2021 Behavioral Risk Factor Surveillance System (BRFSS). Our secondary objective was to analyze the relationship between various demographic factors and the age of T2DM diagnosis. We conducted a cross-sectional analysis of data from the 2021 cycle of the BRFSS. Applying sampling weights, provided by BRFSS, we assessed the prevalence rates of ACEs across sociodemographic variables and utilized binary and multivariable regressions to determine associations between sociodemographic factors and ACE scores on age of T2DM diagnosis. Among the 437,708 respondents, 57,616 (12.6 %) individuals reported having diabetes, with 6901 including responses for age of T2DM diagnosis and ACEs. We found a relationship between ACEs and earlier age of diabetes diagnosis - with individuals experiencing 1-3 ACEs being diagnosed 2.15 years earlier (standard error [SE]=0.48, p<0.001) than those with 0 ACEs, and 6.37 years earlier for individuals experiencing 4+ ACEs (SE=0.61, p<0.001). Significant differences in ACEs and age of diagnosis were also found between ethnoracial groups - compared to White, non-Hispanic individuals with 0 ACEs, the mean age of diagnosis was more than 12 years earlier among those who experienced 4+ ACEs and were either Asian, American Indian/Alaskan Native (AI/AN), or Hispanic. This observational analysis of one-year of BRFSS data found earlier diagnosis of T2DM among adults reporting ACEs compared to those without ACEs, but this varied by racial and ethnic identities. Although early diagnosis is critical in long-term T2DM management, appropriate identification of childhood adversity may be a key component to the development of the disease. This may be achieved through comprehensive child and family resources that target mental health and behavioral factors already known to be associated with T2DM.